Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169290384> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2169290384 endingPage "8" @default.
- W2169290384 startingPage "382" @default.
- W2169290384 abstract "To describe the prostate-specific antigen (PSA) pattern profiles observed after external beam radiotherapy with and without short-term neoadjuvant androgen deprivation therapy (ST-ADT) and to report the association of established posttreatment PSA patterns with long-term disease-free survival outcomes.A total of 1,665 patients were treated with conformal external beam radiotherapy for clinically localized prostate cancer. Of 570 patients who had the requisite>10 consecutive PSA measurements for statistical analysis, 194 patients received a median of 3 months of ADT before radiotherapy and 376 were treated with radiotherapy alone. The median follow up was 103 months.In the group treated with ST-ADT, three distinct postradiotherapy PSA patterns were identified: a stable trend (44%), an increasing trend followed by stabilization of the PSA (25%), and an increasing trend (31%). Among the subgroup that demonstrated a rising and subsequent stabilizing patterns, PSA levels had gradually risen to a median value of 0.9 ng/mL after therapy, stabilized, and remained durably suppressed. The only identified trends among patients treated with external beam radiotherapy without ST-ADT were declining PSA levels followed by stable PSA trends or declining patterns followed by rising levels. Patients whose PSA levels stabilized after an initial rise or those with slowly rising PSA profiles had a lower incidence of distant metastasis compared to those with accelerated rises after therapy.For those treated with external beam radiotherapy in conjunction with ST-ADT, a significant percentage who develop a rising PSA after treatment are expected to manifest subsequent stabilization at plateaued levels of approximately 1.0 ng/mL, which can remain durably suppressed. The likelihood of distant metastasis in these patients is low despite the PSA stabilization at levels 1.0 ng/mL or higher and comparable to outcomes observed for those with lower nonrising PSA values." @default.
- W2169290384 created "2016-06-24" @default.
- W2169290384 creator A5035446911 @default.
- W2169290384 creator A5058728327 @default.
- W2169290384 creator A5060678769 @default.
- W2169290384 creator A5077103441 @default.
- W2169290384 creator A5081611907 @default.
- W2169290384 date "2006-10-01" @default.
- W2169290384 modified "2023-10-16" @default.
- W2169290384 title "Evaluation of postradiotherapy PSA patterns and correlation with 10-year disease free survival outcomes for prostate cancer." @default.
- W2169290384 cites W1969931964 @default.
- W2169290384 cites W1975634037 @default.
- W2169290384 cites W1981924282 @default.
- W2169290384 cites W2005055100 @default.
- W2169290384 cites W2011824883 @default.
- W2169290384 cites W2014320016 @default.
- W2169290384 cites W2025053238 @default.
- W2169290384 cites W2026566205 @default.
- W2169290384 cites W2077618811 @default.
- W2169290384 cites W2081224952 @default.
- W2169290384 cites W2089403922 @default.
- W2169290384 cites W2092917417 @default.
- W2169290384 cites W2096600898 @default.
- W2169290384 cites W2103003357 @default.
- W2169290384 cites W2108776877 @default.
- W2169290384 cites W2132163969 @default.
- W2169290384 cites W4320801101 @default.
- W2169290384 doi "https://doi.org/10.1016/j.ijrobp.2006.05.012" @default.
- W2169290384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16965990" @default.
- W2169290384 hasPublicationYear "2006" @default.
- W2169290384 type Work @default.
- W2169290384 sameAs 2169290384 @default.
- W2169290384 citedByCount "11" @default.
- W2169290384 countsByYear W21692903842013 @default.
- W2169290384 countsByYear W21692903842020 @default.
- W2169290384 crossrefType "journal-article" @default.
- W2169290384 hasAuthorship W2169290384A5035446911 @default.
- W2169290384 hasAuthorship W2169290384A5058728327 @default.
- W2169290384 hasAuthorship W2169290384A5060678769 @default.
- W2169290384 hasAuthorship W2169290384A5077103441 @default.
- W2169290384 hasAuthorship W2169290384A5081611907 @default.
- W2169290384 hasConcept C120665830 @default.
- W2169290384 hasConcept C121332964 @default.
- W2169290384 hasConcept C121608353 @default.
- W2169290384 hasConcept C126322002 @default.
- W2169290384 hasConcept C126894567 @default.
- W2169290384 hasConcept C141071460 @default.
- W2169290384 hasConcept C143998085 @default.
- W2169290384 hasConcept C2775908122 @default.
- W2169290384 hasConcept C2777899217 @default.
- W2169290384 hasConcept C2780192828 @default.
- W2169290384 hasConcept C2781406297 @default.
- W2169290384 hasConcept C509974204 @default.
- W2169290384 hasConcept C61511704 @default.
- W2169290384 hasConcept C71924100 @default.
- W2169290384 hasConceptScore W2169290384C120665830 @default.
- W2169290384 hasConceptScore W2169290384C121332964 @default.
- W2169290384 hasConceptScore W2169290384C121608353 @default.
- W2169290384 hasConceptScore W2169290384C126322002 @default.
- W2169290384 hasConceptScore W2169290384C126894567 @default.
- W2169290384 hasConceptScore W2169290384C141071460 @default.
- W2169290384 hasConceptScore W2169290384C143998085 @default.
- W2169290384 hasConceptScore W2169290384C2775908122 @default.
- W2169290384 hasConceptScore W2169290384C2777899217 @default.
- W2169290384 hasConceptScore W2169290384C2780192828 @default.
- W2169290384 hasConceptScore W2169290384C2781406297 @default.
- W2169290384 hasConceptScore W2169290384C509974204 @default.
- W2169290384 hasConceptScore W2169290384C61511704 @default.
- W2169290384 hasConceptScore W2169290384C71924100 @default.
- W2169290384 hasIssue "2" @default.
- W2169290384 hasLocation W21692903841 @default.
- W2169290384 hasLocation W21692903842 @default.
- W2169290384 hasOpenAccess W2169290384 @default.
- W2169290384 hasPrimaryLocation W21692903841 @default.
- W2169290384 hasRelatedWork W1225174559 @default.
- W2169290384 hasRelatedWork W1973836296 @default.
- W2169290384 hasRelatedWork W2030798726 @default.
- W2169290384 hasRelatedWork W2112080888 @default.
- W2169290384 hasRelatedWork W2346619617 @default.
- W2169290384 hasRelatedWork W2417374591 @default.
- W2169290384 hasRelatedWork W2597301728 @default.
- W2169290384 hasRelatedWork W2789553788 @default.
- W2169290384 hasRelatedWork W4308663128 @default.
- W2169290384 hasRelatedWork W4319748405 @default.
- W2169290384 hasVolume "66" @default.
- W2169290384 isParatext "false" @default.
- W2169290384 isRetracted "false" @default.
- W2169290384 magId "2169290384" @default.
- W2169290384 workType "article" @default.