Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169307972> ?p ?o ?g. }
- W2169307972 abstract "Complex biological systems rely on cell surface cues that govern cellular self-recognition and selective interactions with appropriate partners. Molecular diversification of cell surface recognition molecules through DNA recombination and complex alternative splicing has emerged as an important principle for encoding such interactions. However, the lack of tools to specifically detect and quantify receptor protein isoforms is a major impediment to functional studies. We here developed a workflow for targeted mass spectrometry by selected reaction monitoring that permits quantitative assessment of highly diversified protein families. We apply this workflow to dissecting the molecular diversity of the neuronal neurexin receptors and uncover an alternative splicing-dependent recognition code for synaptic ligands." @default.
- W2169307972 created "2016-06-24" @default.
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- W2169307972 date "2015-05-18" @default.
- W2169307972 modified "2023-10-13" @default.
- W2169307972 title "Quantitative isoform-profiling of highly diversified recognition molecules" @default.
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- W2169307972 doi "https://doi.org/10.7554/elife.07794" @default.
- W2169307972 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4489214" @default.
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- W2169307972 hasPublicationYear "2015" @default.
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