FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169333707> ?p ?o ?g. }

• W2169333707 endingPage "8" @default.
• W2169333707 startingPage "1" @default.
• W2169333707 abstract "Ophidian envenomation is an important health problem in Brazil and other South American countries. In folk medicine, especially in developing countries, several vegetal species are employed for the treatment of snakebites in communities that lack prompt access to serum therapy. However, the identification and characterization of the effects of several new plants or their isolated compounds, which are able to inhibit the activities of snake venom, are extremely important and such studies are imperative. Snake venom contains several organic and inorganic compounds; phospholipases A 2 (PLA 2 s) are one of the principal toxic components of venom. PLA 2 s display a wide variety of pharmacological activities, such as neurotoxicity, myotoxicity, cardiotoxicity, anticoagulant, hemorrhagic, and edema-inducing effects. PLA 2 inhibition is of pharmacological and therapeutic interests as these enzymes are involved in several inflammatory diseases. This review describes the results of several studies of plant extracts and their isolated active principles, when used against crude snake venoms or their toxic fractions. Isolated inhibitors, such as steroids, terpenoids, and phenolic compounds, are able to inhibit PLA 2 s from different snake venoms. The design of specific inhibitors of PLA 2 s might help in the development of new pharmaceutical drugs, more specific antivenom, or even as alternative approaches for treating snakebites." @default.
• W2169333707 created "2016-06-24" @default.
• W2169333707 creator A5020737475 @default.
• W2169333707 creator A5025985830 @default.
• W2169333707 creator A5031541151 @default.
• W2169333707 creator A5032403437 @default.
• W2169333707 creator A5033231303 @default.
• W2169333707 creator A5042938426 @default.
• W2169333707 creator A5044683279 @default.
• W2169333707 creator A5054916263 @default.
• W2169333707 creator A5065728152 @default.
• W2169333707 creator A5067537875 @default.
• W2169333707 creator A5069369574 @default.
• W2169333707 creator A5080466642 @default.
• W2169333707 creator A5088876156 @default.
• W2169333707 date "2013-01-01" @default.
• W2169333707 modified "2023-10-16" @default.
• W2169333707 title "Snake Venom PLA_<b>2</b>s Inhibitors Isolated from Brazilian Plants: Synthetic and Natural Molecules" @default.
• W2169333707 cites W1575949823 @default.
• W2169333707 cites W1963620866 @default.
• W2169333707 cites W1964256253 @default.
• W2169333707 cites W1976657679 @default.
• W2169333707 cites W1977307953 @default.
• W2169333707 cites W1981639053 @default.
• W2169333707 cites W1986059087 @default.
• W2169333707 cites W1989021340 @default.
• W2169333707 cites W1990143900 @default.
• W2169333707 cites W1990147960 @default.
• W2169333707 cites W1991274016 @default.
• W2169333707 cites W1995009837 @default.
• W2169333707 cites W1995605555 @default.
• W2169333707 cites W1998632105 @default.
• W2169333707 cites W2000402588 @default.
• W2169333707 cites W2001200650 @default.
• W2169333707 cites W2001643884 @default.
• W2169333707 cites W2003044656 @default.
• W2169333707 cites W2003075532 @default.
• W2169333707 cites W2003202896 @default.
• W2169333707 cites W2003312064 @default.
• W2169333707 cites W2005451635 @default.
• W2169333707 cites W2005487807 @default.
• W2169333707 cites W2007187686 @default.
• W2169333707 cites W2009362033 @default.
• W2169333707 cites W2009508849 @default.
• W2169333707 cites W2010422388 @default.
• W2169333707 cites W2014620003 @default.
• W2169333707 cites W2020921331 @default.
• W2169333707 cites W2022533321 @default.
• W2169333707 cites W2022806475 @default.
• W2169333707 cites W2023363157 @default.
• W2169333707 cites W2025395935 @default.
• W2169333707 cites W2027837829 @default.
• W2169333707 cites W2032713792 @default.
• W2169333707 cites W2034283588 @default.
• W2169333707 cites W2036400747 @default.
• W2169333707 cites W2040943875 @default.
• W2169333707 cites W2042694255 @default.
• W2169333707 cites W2050132483 @default.
• W2169333707 cites W2051507162 @default.
• W2169333707 cites W2051952693 @default.
• W2169333707 cites W2052379849 @default.
• W2169333707 cites W2056097440 @default.
• W2169333707 cites W2059380727 @default.
• W2169333707 cites W2059603317 @default.
• W2169333707 cites W2060141865 @default.
• W2169333707 cites W2060722082 @default.
• W2169333707 cites W2066084409 @default.
• W2169333707 cites W2067843288 @default.
• W2169333707 cites W2070616776 @default.
• W2169333707 cites W2071369880 @default.
• W2169333707 cites W2071876927 @default.
• W2169333707 cites W2072606531 @default.
• W2169333707 cites W2072869590 @default.
• W2169333707 cites W2084835801 @default.
• W2169333707 cites W2085453879 @default.
• W2169333707 cites W2087347240 @default.
• W2169333707 cites W2088417031 @default.
• W2169333707 cites W2090085869 @default.
• W2169333707 cites W2091071501 @default.
• W2169333707 cites W2093101402 @default.
• W2169333707 cites W2106128990 @default.
• W2169333707 cites W2122870421 @default.
• W2169333707 cites W2127083610 @default.
• W2169333707 cites W2136165433 @default.
• W2169333707 cites W2139051050 @default.
• W2169333707 cites W2144682888 @default.
• W2169333707 cites W2163532446 @default.
• W2169333707 cites W2330826114 @default.
• W2169333707 cites W2952459654 @default.
• W2169333707 doi "https://doi.org/10.1155/2013/153045" @default.
• W2169333707 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3793501" @default.
• W2169333707 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24171158" @default.
• W2169333707 hasPublicationYear "2013" @default.
• W2169333707 type Work @default.
• W2169333707 sameAs 2169333707 @default.
• W2169333707 citedByCount "46" @default.
• W2169333707 countsByYear W21693337072014 @default.
• W2169333707 countsByYear W21693337072015 @default.

• next