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• W2169337841 abstract "Non-nucleoside inhibitors of HIV-1 reverse transcriptase (HIV-RT) are reported that feature extension into the entrance channel near Glu138. Complexes of the parent anilinylpyrimidine 1 and the morpholinoethoxy analog 2j with HIV-RT have received crystallographic characterization confirming the designs. Measurement of aqueous solubilities of 2j, 2k, the parent triazene 2a, and other NNRTIs demonstrate profound benefits for addition of the morpholinyl substituent." @default.
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• W2169337841 date "2013-09-01" @default.
• W2169337841 modified "2023-09-27" @default.
• W2169337841 title "Extension into the entrance channel of HIV-1 reverse transcriptase—Crystallography and enhanced solubility" @default.
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• W2169337841 doi "https://doi.org/10.1016/j.bmcl.2013.06.093" @default.
• W2169337841 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3761378" @default.
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