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- W2169354857 abstract "OBJECTIVE: To compare the cost-effectiveness ratio (CER, the average dollar cost per live delivery achieved) of embryo donation (ED) with that of oocyte donation (OD). DESIGN: 1) Comparison of cost-effectiveness of OD to ED (one cycle), calculated from published costs and delivery rates of OD nationally and of ED from 7 programs. 2) Comparison of cost-effectiveness of OD and ED for up to three cycles, from 5 IVF centers with both types of programs. MATERIALS AND METHODS: First, the cost of a single cycle of OD in the USA was estimated by averaging the charges of 15 geographically representative IVF centers as published on their web sites. This cost was divided by the delivery rate for OD cycles published in the 2005 SART on-line database to obtain a single-cycle CER for OD. Seven ED programs (four IVF centers and three programs that match embryo donors with recipients) supplied ED costs; these were combined in a weighted average and divided by the ED delivery rate for these programs that has been published previously. Second, five IVF centers that perform both OD and ED supplied average costs for first (fresh) and second and third (cryopreserved) cycles for OD, and the numbers of patients participating and delivering in each cycle (to a maximum of one delivery per patient). They also supplied the same information for first, second, and third (all cryopreserved) cycles of ED. This enabled the calculation of CERs for OD and ED for couples pursuing pregnancy by either of these routes. RESULTS: We estimate that a single cycle of OD costs $42,470 per live delivery. This compares to $21,990 per live delivery for a single cycle of ED. The five participating centers experienced a single-cycle CER for OD of $37,285 (about $5000 less than the national average). Couples experiencing up to three cycles of OD paid $30,653 per live delivery, compared to $13,505 for ED. Three-cycle CERs are lower because subsequent OD cycles require no additional oocyte retrievals and additional ED cycles require no further home studies and counseling yet produce additional live births. CONCLUSIONS: From either perspective, embryo donation is about one half the cost of oocyte donation per live delivery. Embryo donation should be considered for couples whose reproductive options are limited for medical or financial reasons." @default.
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- W2169354857 date "2008-09-01" @default.
- W2169354857 modified "2023-10-14" @default.
- W2169354857 title "Embryo donation is cost-effective compared to oocyte donation" @default.
- W2169354857 doi "https://doi.org/10.1016/j.fertnstert.2008.07.1369" @default.
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