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- W2169361208 abstract "A strategy for using processed, digitized images of one-dimensional electrophoretic gels to facilitate the analysis of large sets of overlapping clones is described. The images are acquired from fluorescently stained gels or from transilluminated gel photographs using a cooled, solid-state charge-coupled device camera. By employing sets of bands in the size-standard lanes as reference points, all the gel images are spatially normalized to a common reference template. After normalization, lane images from different gels can be compared as though the gels had been electrophoresed under identical, uniform-field conditions. Applications of this procedure to the analysis of a large set of overlapping lambda clones from chromosome VII of Saccharomyces cerevisiae and to the estimation of fragment sizes are illustrated." @default.
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- W2169361208 date "1990-09-01" @default.
- W2169361208 modified "2023-09-25" @default.
- W2169361208 title "Spatial normalization of one-dimensional electrophoretic gel images" @default.
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- W2169361208 doi "https://doi.org/10.1016/0888-7543(90)90233-k" @default.
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