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• W2169373515 abstract "Short-course treatments for streptococcal pharyngotonsillitis with oral cephalosporins or macrolides have resulted in a similar bacteriological and clinical cure rate and better compliance compared with the conventional 10-day course. One hundred and thirty eight of 420 recruited patients had a positive culture for Streptococcus pyogenes and were randomly assigned to receive cefaclor (25 mg/kg/bid) for a 5-day (70 patients) or 10-day (68 patients) course. Patients were assessed clinically and bacteriologically 2–3 days after completing the course and followed up after 20–30 days. All 420 recruited patients belonged to a population of 2800 children who had been previously screened for a streptococcal carrier state to exclude carriers from final evaluation. Clinical cure and bacterial eradication was recorded in 92.8 and 92.6% of patients in groups A and B, respectively. Therefore, short-course therapy with cefaclor may offer an effective alternative treatment to conventional regimens, with potential for better compliance." @default.
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• W2169373515 date "2001-10-01" @default.
• W2169373515 modified "2023-09-23" @default.
• W2169373515 title "Short-course therapy with cefaclor for treatment of streptococcal pharyngotonsillitis" @default.
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• W2169373515 doi "https://doi.org/10.1016/s0924-8579(01)00417-4" @default.
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