FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169392458> ?p ?o ?g. }

• W2169392458 endingPage "50" @default.
• W2169392458 startingPage "141" @default.
• W2169392458 abstract "Leptin, a peptide secreted from adipose tissue, plays an important role in the regulation of food intake and energy expenditure. In obese patients, plasma leptin levels are elevated and obesity is one of the major risk factors for cardiovascular diseases. Therefore, in this study, we investigated the effect of leptin on vascular smooth muscle cell (VSMC) functions. Cultured rat aortic VSMC expressed 130-kDa short form of leptin receptor. Leptin stimulated both proliferation and migration of VSMC. Leptin stimulated phosphorylation and activation of mitogen-activated protein (MAP) kinases, and also increased phosphatidylinositol (PI) 3-kinase activity. Further, two distinct PI 3-kinase inhibitors, wortmannin and LY294002 inhibited the migratory effect of leptin. These results demonstrate that leptin is a proliferative and migratory factor for VSMC, implying that leptin may play a role in the formation and development of vascular lesions." @default.
• W2169392458 created "2016-06-24" @default.
• W2169392458 creator A5021321525 @default.
• W2169392458 creator A5035596282 @default.
• W2169392458 creator A5074192666 @default.
• W2169392458 date "2001-06-01" @default.
• W2169392458 modified "2023-09-29" @default.
• W2169392458 title "Leptin stimulates rat aortic smooth muscle cell proliferation and migration." @default.
• W2169392458 cites W1525154317 @default.
• W2169392458 cites W1529396499 @default.
• W2169392458 cites W1602494224 @default.
• W2169392458 cites W1779691448 @default.
• W2169392458 cites W1969161473 @default.
• W2169392458 cites W1996713062 @default.
• W2169392458 cites W2006592185 @default.
• W2169392458 cites W2016994959 @default.
• W2169392458 cites W201744686 @default.
• W2169392458 cites W2024484448 @default.
• W2169392458 cites W2025390659 @default.
• W2169392458 cites W2025846514 @default.
• W2169392458 cites W2029999922 @default.
• W2169392458 cites W2038150521 @default.
• W2169392458 cites W2043429832 @default.
• W2169392458 cites W2044153433 @default.
• W2169392458 cites W2054770365 @default.
• W2169392458 cites W2056383195 @default.
• W2169392458 cites W2061755142 @default.
• W2169392458 cites W2063992063 @default.
• W2169392458 cites W2064129448 @default.
• W2169392458 cites W2067030980 @default.
• W2169392458 cites W2069038722 @default.
• W2169392458 cites W2081876438 @default.
• W2169392458 cites W2091177021 @default.
• W2169392458 cites W2095308289 @default.
• W2169392458 cites W2101466853 @default.
• W2169392458 cites W2109311297 @default.
• W2169392458 cites W2111232488 @default.
• W2169392458 cites W2118678876 @default.
• W2169392458 cites W2125510262 @default.
• W2169392458 cites W2126426760 @default.
• W2169392458 cites W2135405968 @default.
• W2169392458 cites W2137369602 @default.
• W2169392458 cites W2137736712 @default.
• W2169392458 cites W2138987897 @default.
• W2169392458 cites W2218441948 @default.
• W2169392458 cites W2317730087 @default.
• W2169392458 cites W2320856221 @default.
• W2169392458 cites W2398888674 @default.
• W2169392458 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11729375" @default.
• W2169392458 hasPublicationYear "2001" @default.
• W2169392458 type Work @default.
• W2169392458 sameAs 2169392458 @default.
• W2169392458 citedByCount "100" @default.
• W2169392458 countsByYear W21693924582012 @default.
• W2169392458 countsByYear W21693924582013 @default.
• W2169392458 countsByYear W21693924582014 @default.
• W2169392458 countsByYear W21693924582015 @default.
• W2169392458 countsByYear W21693924582016 @default.
• W2169392458 countsByYear W21693924582017 @default.
• W2169392458 countsByYear W21693924582018 @default.
• W2169392458 countsByYear W21693924582019 @default.
• W2169392458 countsByYear W21693924582020 @default.
• W2169392458 countsByYear W21693924582021 @default.
• W2169392458 countsByYear W21693924582022 @default.
• W2169392458 countsByYear W21693924582023 @default.
• W2169392458 crossrefType "journal-article" @default.
• W2169392458 hasAuthorship W2169392458A5021321525 @default.
• W2169392458 hasAuthorship W2169392458A5035596282 @default.
• W2169392458 hasAuthorship W2169392458A5074192666 @default.
• W2169392458 hasConcept C11960822 @default.
• W2169392458 hasConcept C126322002 @default.
• W2169392458 hasConcept C134018914 @default.
• W2169392458 hasConcept C171089720 @default.
• W2169392458 hasConcept C184235292 @default.
• W2169392458 hasConcept C185592680 @default.
• W2169392458 hasConcept C2776912716 @default.
• W2169392458 hasConcept C2778308172 @default.
• W2169392458 hasConcept C2779395532 @default.
• W2169392458 hasConcept C2780610907 @default.
• W2169392458 hasConcept C2780613262 @default.
• W2169392458 hasConcept C2992686903 @default.
• W2169392458 hasConcept C511355011 @default.
• W2169392458 hasConcept C55493867 @default.
• W2169392458 hasConcept C62112901 @default.
• W2169392458 hasConcept C71924100 @default.
• W2169392458 hasConcept C86803240 @default.
• W2169392458 hasConcept C95444343 @default.
• W2169392458 hasConceptScore W2169392458C11960822 @default.
• W2169392458 hasConceptScore W2169392458C126322002 @default.
• W2169392458 hasConceptScore W2169392458C134018914 @default.
• W2169392458 hasConceptScore W2169392458C171089720 @default.
• W2169392458 hasConceptScore W2169392458C184235292 @default.
• W2169392458 hasConceptScore W2169392458C185592680 @default.
• W2169392458 hasConceptScore W2169392458C2776912716 @default.
• W2169392458 hasConceptScore W2169392458C2778308172 @default.
• W2169392458 hasConceptScore W2169392458C2779395532 @default.
• W2169392458 hasConceptScore W2169392458C2780610907 @default.
• W2169392458 hasConceptScore W2169392458C2780613262 @default.

• next