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• W2169392968 abstract "To determine the effects of biophysical parameters (e.g. charge, hydrophobicity, helicity) of peptides on the mechanism of anticancer activity, we applied a single molecule technique-force spectroscopy based on atomic force microscope (AFM)-to study the interaction force at the single molecule level. The activity of the peptide and analogs against HeLa cells exhibited a strong correlation with the hydrophobicity of peptides. Our results indicated that the action mode between α-helical peptides and cancer cells was largely hydrophobicity-dependent." @default.
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• W2169392968 date "2012-01-01" @default.
• W2169392968 modified "2023-10-18" @default.
• W2169392968 title "The study of single anticancer peptides interacting with HeLa cell membranes by single molecule force spectroscopy" @default.
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• W2169392968 doi "https://doi.org/10.1039/c2nr11541g" @default.
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