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- W2169428948 abstract "Objective. To demonstrate the association between clinical improvement in substance-related problems and psychiatric symptoms in psychotic patients. Methods. The data was gathered from randomised controlled trial of brief intervention for substance-related problem in psychosis. The Alcohol, Smoking, Substance Involvement Screening Test (ASSIST) was used to identify substance use in the moderate risk range among psychotic patients. 169 participants were randomised to treatment-as-usual (TAU), single-session Brief Intervention (BI), or single-session BI with family support (BI-FS). The Jacobson & Truax Reliable Chang Index (RCI) was used to explore the clinical significant individual change from baseline to six months of the ASSIST score and classified into “Clinically improved – CI” or “Not improved – NI”. The outcome was the change score of Brief Psychiatric Rating Scale (BPRS). A two level mixed effects model was fit to determine differences in outcomes between RCI outcomes. Results. 54 participants (32%) were classified into CI. Compared to NI, participants in CI reported a significant reduction in both total and all subscales of BPRS score. The interaction term was significant in total, positive and negative symptoms subscale between CI and BI-FS. Conclusion. Improvement in substance-related problems can improve psychotic symptoms. BI-FS had an additive effect to improve some subscales." @default.
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- W2169428948 date "2014-09-01" @default.
- W2169428948 modified "2023-10-14" @default.
- W2169428948 title "SY03-1-2 * ISAM FELLOWSHIP THE ASSOCIATION BETWEEN CLINICAL IMPROVEMENT IN SUBSTANCE-RELATED PROBLEMS AND PSYCHIATRIC SYMPTOMS IN PSYCHOSIS: A POST-HOC ANALYSIS" @default.
- W2169428948 doi "https://doi.org/10.1093/alcalc/agu052.11" @default.
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