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• W2169444481 abstract "ther asthma nor allergic rhinitis, from patients with food allergy and concomitant respiratory involvement. We hypothesized that findings in sputum analyses or perhaps the specific types of aeroallergens might hold the answers to these questions. We designed this comparative study to evalu - ate airway involvement of young adult patients with food allergy alone and patients with food allergy and known asthma or allergic rhinitis by performing both sputum induction and methacholine inhalation challenge. We also compared the results of aeroallergen skin tests in the various patient groups and in allegedly healthy Abstract Background: Dyspnea may be a presenting symptom of type I food hypersensitivity; bronchial hyperactivity, without known asthma, can coexist in patients with food allergy. Objective: To evaluate airway involvement in young adult patients with food allergy and no asthma and compare the find- ings to those of patients with food allergy and asthma, with food allergy and allergic rhinitis, with asthma and no food allergy, and of apparently healthy controls. Methods: The evaluation involved prick skin test to food (65 allergens) and inhalants (24 allergens), spirometry, methacholine inhalation challenge, and induced sputum for cell analysis. The five groups consisted of 18 patients with food allergy alone, 11 with food allergy and asthma, 13 with food allergy and allergic rhinitis, 10 with asthma alone, and 10 controls. Results: Patients with food allergy alone were mainly (86%) skin sensitive to pollens. Those with either asthma or allergic rhinitis were mainly (95%) sensitive to mites. BHR was detected in 40% of the patients with food allergy alone, 55% of the patients with allergic rhinitis, and 100% of the patients with asthma. Cell counts in the sputum of patients with asthma and in those with food allergy and asthma showed higher eosinophil counts compared to those with food allergy and allergic rhinitis. Patients with food allergy and no asthma, regardless of BHR status, had mainly neutrophils in the sputum. Conclusions: Patients with food allergy are highly likely to have concomitant asymptomatic BHR. Mite sensitivity in patients with food allergy predicts respiratory allergy (either asthma or allergic rhinitis). High eosinophil levels in the sputum of food allergy patients predict respiratory involvement." @default.
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• W2169444481 date "2005-12-01" @default.
• W2169444481 modified "2023-09-23" @default.
• W2169444481 title "Bronchial hyperactivity, sputum analysis and skin prick test to inhalant allergens in patients with symptomatic food hypersensitivity." @default.
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