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• W2169456871 endingPage "530" @default.
• W2169456871 startingPage "521" @default.
• W2169456871 abstract "Virus survival and the ability to cause disease in mammalian hosts depend on their ability to avoid recognition and control by the interferon signal transduction and effector pathways. Flaviviruses comprise a large family of nonsegmented positive sense enveloped cytoplasmic RNA viruses, many of which are globally important human pathogens. Although the mechanistic details are still being dissected, new insight has emerged as to how a flavivirus minimizes the antiviral activity of type I interferon (IFN) to establish productive and potentially lethal infection. This review will summarize our current understanding of how mammalian cells recognize flaviviruses to induce an inhibitory IFN response and the countermeasures this group of viruses has evolved to antagonize this response." @default.
• W2169456871 created "2016-06-24" @default.
• W2169456871 creator A5016005915 @default.
• W2169456871 date "2009-09-01" @default.
• W2169456871 modified "2023-10-18" @default.
• W2169456871 title "Mechanisms of Evasion of the Type I Interferon Antiviral Response by Flaviviruses" @default.
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