FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169476614> ?p ?o ?g. }

• W2169476614 endingPage "829" @default.
• W2169476614 startingPage "820" @default.
• W2169476614 abstract "The karyotype is a strong independent prognostic factor in myelodysplastic syndromes (MDS). Since the implementation of the International Prognostic Scoring System (IPSS) in 1997, knowledge concerning the prognostic impact of abnormalities has increased substantially. The present study proposes a new and comprehensive cytogenetic scoring system based on an international data collection of 2,902 patients.Patients were included from the German-Austrian MDS Study Group (n = 1,193), the International MDS Risk Analysis Workshop (n = 816), the Spanish Hematological Cytogenetics Working Group (n = 849), and the International Working Group on MDS Cytogenetics (n = 44) databases. Patients with primary MDS and oligoblastic acute myeloid leukemia (AML) after MDS treated with supportive care only were evaluated for overall survival (OS) and AML evolution. Internal validation by bootstrap analysis and external validation in an independent patient cohort were performed to confirm the results.In total, 19 cytogenetic categories were defined, providing clear prognostic classification in 91% of all patients. The abnormalities were classified into five prognostic subgroups (P < .001): very good (median OS, 61 months; hazard ratio [HR], 0.5; n = 81); good (49 months; HR, 1.0 [reference category]; n = 1,809); intermediate (26 months; HR, 1.6; n = 529); poor (16 months; HR, 2.6; n = 148); and very poor (6 months; HR, 4.2; n = 187). The internal and external validations confirmed the results of the score.In conclusion, these data should contribute to the ongoing efforts to update the IPSS by refining the cytogenetic risk categories." @default.
• W2169476614 created "2016-06-24" @default.
• W2169476614 creator A5006306448 @default.
• W2169476614 creator A5011302710 @default.
• W2169476614 creator A5025663121 @default.
• W2169476614 creator A5026347795 @default.
• W2169476614 creator A5026592803 @default.
• W2169476614 creator A5027149922 @default.
• W2169476614 creator A5030067333 @default.
• W2169476614 creator A5036349678 @default.
• W2169476614 creator A5037972294 @default.
• W2169476614 creator A5041683169 @default.
• W2169476614 creator A5042537187 @default.
• W2169476614 creator A5043227502 @default.
• W2169476614 creator A5043678326 @default.
• W2169476614 creator A5047053024 @default.
• W2169476614 creator A5047951694 @default.
• W2169476614 creator A5048030695 @default.
• W2169476614 creator A5050118017 @default.
• W2169476614 creator A5053689963 @default.
• W2169476614 creator A5055382114 @default.
• W2169476614 creator A5061026876 @default.
• W2169476614 creator A5061869444 @default.
• W2169476614 creator A5063615217 @default.
• W2169476614 creator A5065804627 @default.
• W2169476614 creator A5067407128 @default.
• W2169476614 creator A5072355780 @default.
• W2169476614 creator A5080057087 @default.
• W2169476614 creator A5082287365 @default.
• W2169476614 creator A5090793417 @default.
• W2169476614 date "2012-03-10" @default.
• W2169476614 modified "2023-10-15" @default.
• W2169476614 title "New Comprehensive Cytogenetic Scoring System for Primary Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia After MDS Derived From an International Database Merge" @default.
• W2169476614 cites W121813311 @default.
• W2169476614 cites W187238933 @default.
• W2169476614 cites W1971885624 @default.
• W2169476614 cites W1975371333 @default.
• W2169476614 cites W1975470759 @default.
• W2169476614 cites W1991069555 @default.
• W2169476614 cites W2022106508 @default.
• W2169476614 cites W2038252730 @default.
• W2169476614 cites W2048159897 @default.
• W2169476614 cites W2059896614 @default.
• W2169476614 cites W2061862949 @default.
• W2169476614 cites W2062078763 @default.
• W2169476614 cites W2064785868 @default.
• W2169476614 cites W2093845572 @default.
• W2169476614 cites W2117291755 @default.
• W2169476614 cites W2129925362 @default.
• W2169476614 cites W2162154486 @default.
• W2169476614 cites W2296225964 @default.
• W2169476614 cites W4253916874 @default.
• W2169476614 cites W4293241248 @default.
• W2169476614 cites W4298872162 @default.
• W2169476614 doi "https://doi.org/10.1200/jco.2011.35.6394" @default.
• W2169476614 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4874200" @default.
• W2169476614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22331955" @default.
• W2169476614 hasPublicationYear "2012" @default.
• W2169476614 type Work @default.
• W2169476614 sameAs 2169476614 @default.
• W2169476614 citedByCount "561" @default.
• W2169476614 countsByYear W21694766142012 @default.
• W2169476614 countsByYear W21694766142013 @default.
• W2169476614 countsByYear W21694766142014 @default.
• W2169476614 countsByYear W21694766142015 @default.
• W2169476614 countsByYear W21694766142016 @default.
• W2169476614 countsByYear W21694766142017 @default.
• W2169476614 countsByYear W21694766142018 @default.
• W2169476614 countsByYear W21694766142019 @default.
• W2169476614 countsByYear W21694766142020 @default.
• W2169476614 countsByYear W21694766142021 @default.
• W2169476614 countsByYear W21694766142022 @default.
• W2169476614 countsByYear W21694766142023 @default.
• W2169476614 crossrefType "journal-article" @default.
• W2169476614 hasAuthorship W2169476614A5006306448 @default.
• W2169476614 hasAuthorship W2169476614A5011302710 @default.
• W2169476614 hasAuthorship W2169476614A5025663121 @default.
• W2169476614 hasAuthorship W2169476614A5026347795 @default.
• W2169476614 hasAuthorship W2169476614A5026592803 @default.
• W2169476614 hasAuthorship W2169476614A5027149922 @default.
• W2169476614 hasAuthorship W2169476614A5030067333 @default.
• W2169476614 hasAuthorship W2169476614A5036349678 @default.
• W2169476614 hasAuthorship W2169476614A5037972294 @default.
• W2169476614 hasAuthorship W2169476614A5041683169 @default.
• W2169476614 hasAuthorship W2169476614A5042537187 @default.
• W2169476614 hasAuthorship W2169476614A5043227502 @default.
• W2169476614 hasAuthorship W2169476614A5043678326 @default.
• W2169476614 hasAuthorship W2169476614A5047053024 @default.
• W2169476614 hasAuthorship W2169476614A5047951694 @default.
• W2169476614 hasAuthorship W2169476614A5048030695 @default.
• W2169476614 hasAuthorship W2169476614A5050118017 @default.
• W2169476614 hasAuthorship W2169476614A5053689963 @default.
• W2169476614 hasAuthorship W2169476614A5055382114 @default.
• W2169476614 hasAuthorship W2169476614A5061026876 @default.
• W2169476614 hasAuthorship W2169476614A5061869444 @default.
• W2169476614 hasAuthorship W2169476614A5063615217 @default.
• W2169476614 hasAuthorship W2169476614A5065804627 @default.
• W2169476614 hasAuthorship W2169476614A5067407128 @default.

• next