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• W2169496359 abstract "Abstract The human genome encodes several ubiquitin-like (UBL) domain proteins (UDPs). Members of this protein family are involved in a variety of cellular functions and many are connected to the ubiquitin proteasome system, an essential pathway for protein degradation in eukaryotic cells. Despite their structural similarity, the UBL domains appear to have a range of different targets, resulting in a considerable diversity with respect to UDP function. Here, we give a short summary of the biochemical and physiological roles of the UDPs, which have been linked to human diseases including neurodegeneration and cancer. Publication history: Republished from Current BioData's Targeted Proteins database (TPdb; http://www.targetedproteinsdb.com )." @default.
• W2169496359 created "2016-06-24" @default.
• W2169496359 creator A5012733196 @default.
• W2169496359 creator A5027634166 @default.
• W2169496359 creator A5070153067 @default.
• W2169496359 creator A5072786803 @default.
• W2169496359 date "2007-11-01" @default.
• W2169496359 modified "2023-10-03" @default.
• W2169496359 title "Ubiquitin domain proteins in disease" @default.
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• W2169496359 doi "https://doi.org/10.1186/1471-2091-8-s1-s1" @default.
• W2169496359 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2106360" @default.
• W2169496359 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18047733" @default.
• W2169496359 hasPublicationYear "2007" @default.
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