FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169558844> ?p ?o ?g. }

• W2169558844 endingPage "1244" @default.
• W2169558844 startingPage "1240" @default.
• W2169558844 abstract "To study the role of vasopressin (VP) in essential hypertension, we examined plasma levels of VP and blood pressure (BP) response to an orally active V1 receptor antagonist, OPC-21268, in hypertensive patients on diets with different sodium contents. Plasma VP was determined in 12 normotensive subjects and 12 patients with mild essential hypertension on a regular sodium diet, and in eight hypertensive patients on a high sodium (250 mmol/day) and a low sodium (25 mmol/day) diet. BP response was examined for 4 h after single oral administration of OPC-21268 (100 mg) or placebo in eight patients on the regular diet, and in six patients on the high and low sodium diets. In four patients on the regular diet, the effects of OPC-21268 on the baroreflex control of heart rate were also examined with intravenous injections of methoxamine. Plasma VP did not differ between the normotensive and hypertensive subjects. Levels of VP in the plasma was higher in the high sodium than in the low sodium period, but the difference was not significant. BP and heart rate did not change significantly after administration of OPC-21268 or placebo under either condition. OPC-21268 also failed to lower BP in salt-sensitive patients on the high sodium diet. The baroreceptor reflex sensitivity was not modified by the administration of OPC-21268. Our results suggest that VP does not play an important role in mild essential hypertension through its action on the V1 receptors regardless of dietary sodium intake. Am J Hypertens 1997;10:1240–1244 © 1997 American Journal of Hypertension, Ltd." @default.
• W2169558844 created "2016-06-24" @default.
• W2169558844 creator A5028636839 @default.
• W2169558844 creator A5032062413 @default.
• W2169558844 creator A5042907884 @default.
• W2169558844 creator A5057681787 @default.
• W2169558844 creator A5063030973 @default.
• W2169558844 date "1997-11-01" @default.
• W2169558844 modified "2023-10-16" @default.
• W2169558844 title "The Role of Vasopressin in Essential Hypertension Plasma Levels and Effects of the V1 Receptor Antagonist OPC-21268 During Different Dietary Sodium Intakes" @default.
• W2169558844 cites W1976242689 @default.
• W2169558844 cites W1985639000 @default.
• W2169558844 cites W2011329611 @default.
• W2169558844 cites W2015325495 @default.
• W2169558844 cites W2020840952 @default.
• W2169558844 cites W2032871939 @default.
• W2169558844 cites W2050952246 @default.
• W2169558844 cites W2072689726 @default.
• W2169558844 cites W2075326368 @default.
• W2169558844 cites W2090971571 @default.
• W2169558844 cites W2101961791 @default.
• W2169558844 cites W2146017735 @default.
• W2169558844 cites W2194150928 @default.
• W2169558844 cites W2201775933 @default.
• W2169558844 cites W2274332843 @default.
• W2169558844 cites W2279432198 @default.
• W2169558844 cites W2401028150 @default.
• W2169558844 cites W2419334940 @default.
• W2169558844 cites W2426141864 @default.
• W2169558844 cites W2464583585 @default.
• W2169558844 doi "https://doi.org/10.1016/s0895-7061(97)00269-0" @default.
• W2169558844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9397242" @default.
• W2169558844 hasPublicationYear "1997" @default.
• W2169558844 type Work @default.
• W2169558844 sameAs 2169558844 @default.
• W2169558844 citedByCount "21" @default.
• W2169558844 countsByYear W21695588442012 @default.
• W2169558844 countsByYear W21695588442013 @default.
• W2169558844 countsByYear W21695588442014 @default.
• W2169558844 countsByYear W21695588442015 @default.
• W2169558844 countsByYear W21695588442017 @default.
• W2169558844 countsByYear W21695588442018 @default.
• W2169558844 countsByYear W21695588442019 @default.
• W2169558844 countsByYear W21695588442020 @default.
• W2169558844 crossrefType "journal-article" @default.
• W2169558844 hasAuthorship W2169558844A5028636839 @default.
• W2169558844 hasAuthorship W2169558844A5032062413 @default.
• W2169558844 hasAuthorship W2169558844A5042907884 @default.
• W2169558844 hasAuthorship W2169558844A5057681787 @default.
• W2169558844 hasAuthorship W2169558844A5063030973 @default.
• W2169558844 hasBestOaLocation W21695588441 @default.
• W2169558844 hasConcept C126322002 @default.
• W2169558844 hasConcept C134018914 @default.
• W2169558844 hasConcept C142724271 @default.
• W2169558844 hasConcept C170493617 @default.
• W2169558844 hasConcept C178790620 @default.
• W2169558844 hasConcept C185592680 @default.
• W2169558844 hasConcept C204787440 @default.
• W2169558844 hasConcept C27081682 @default.
• W2169558844 hasConcept C2776370428 @default.
• W2169558844 hasConcept C2776885963 @default.
• W2169558844 hasConcept C2777097880 @default.
• W2169558844 hasConcept C2777953023 @default.
• W2169558844 hasConcept C537181965 @default.
• W2169558844 hasConcept C71924100 @default.
• W2169558844 hasConcept C79752029 @default.
• W2169558844 hasConcept C84393581 @default.
• W2169558844 hasConcept C90474776 @default.
• W2169558844 hasConceptScore W2169558844C126322002 @default.
• W2169558844 hasConceptScore W2169558844C134018914 @default.
• W2169558844 hasConceptScore W2169558844C142724271 @default.
• W2169558844 hasConceptScore W2169558844C170493617 @default.
• W2169558844 hasConceptScore W2169558844C178790620 @default.
• W2169558844 hasConceptScore W2169558844C185592680 @default.
• W2169558844 hasConceptScore W2169558844C204787440 @default.
• W2169558844 hasConceptScore W2169558844C27081682 @default.
• W2169558844 hasConceptScore W2169558844C2776370428 @default.
• W2169558844 hasConceptScore W2169558844C2776885963 @default.
• W2169558844 hasConceptScore W2169558844C2777097880 @default.
• W2169558844 hasConceptScore W2169558844C2777953023 @default.
• W2169558844 hasConceptScore W2169558844C537181965 @default.
• W2169558844 hasConceptScore W2169558844C71924100 @default.
• W2169558844 hasConceptScore W2169558844C79752029 @default.
• W2169558844 hasConceptScore W2169558844C84393581 @default.
• W2169558844 hasConceptScore W2169558844C90474776 @default.
• W2169558844 hasIssue "11" @default.
• W2169558844 hasLocation W21695588441 @default.
• W2169558844 hasLocation W21695588442 @default.
• W2169558844 hasOpenAccess W2169558844 @default.
• W2169558844 hasPrimaryLocation W21695588441 @default.
• W2169558844 hasRelatedWork W1963761920 @default.
• W2169558844 hasRelatedWork W1966699539 @default.
• W2169558844 hasRelatedWork W1996846474 @default.
• W2169558844 hasRelatedWork W2007102871 @default.
• W2169558844 hasRelatedWork W2025705614 @default.
• W2169558844 hasRelatedWork W2062690991 @default.
• W2169558844 hasRelatedWork W2082669198 @default.
• W2169558844 hasRelatedWork W2091421847 @default.

• next