FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169573044> ?p ?o ?g. }

• W2169573044 endingPage "1526" @default.
• W2169573044 startingPage "1522" @default.
• W2169573044 abstract "Summary Purpose: To evaluate long‐term seizure outcome in children with epilepsy and a focal or hemispheric neuroimaging abnormality. Methods: All children (<18 years and residing in Olmsted County, Minnesota) with new‐onset epilepsy diagnosed between 1980 and 2004 and a single focal lesion on neuroimaging were identified by review of the Rochester Epidemiologic Project database. Outcomes were divided into three categories: (1) seizure freedom for 1 or more years at last follow‐up, (2) ongoing seizures but not medically intractable epilepsy, and (3) medically intractable epilepsy or undergoing epilepsy surgery. We also evaluated the proportion who achieved seizure control without surgical intervention and whether lesion type predicted intractability. Key Findings: Of the 359 children with newly diagnosed epilepsy, 37 (10%) had a focal or hemispheric lesion on neuroimaging. Median age of diagnosis was 89 months (25th percentile 26 months, 75th percentile 142 months) and at follow‐up was 137 months (25th percentile 95 months, 75th percentile 211 months). Eighty‐three percent of children with malformations of cortical development, 67% with mesial temporal sclerosis, 33% with encephalomalacia, and 50% with vascular malformations had intractable epilepsy at follow‐up or underwent resective surgery for medically intractable epilepsy. Among the different etiologies, presence of encephalomalacia predicted the lowest likelihood of medical intractability or undergoing surgery (p < 0.01). At final follow‐up, 24 (65%) of our entire cohort was seizure free. Following surgery, seizure freedom was achieved in 80% with mesial temporal sclerosis, 67% with encephalomalacia, 67% with vascular malformation, and 50% with malformations of cortical development. There was no statistically significant difference between the different etiologies on neuroimaging and seizure freedom after surgery. Twelve children (32%) achieved seizure freedom with medical management alone. Significance: Focal lesions on neuroimaging confer a high risk of medical intractability among children with new‐onset epilepsy. However, 32% of this cohort achieved seizure remission with medical management alone, including 58% with encephalomalacia and 33% with mesial temporal sclerosis." @default.
• W2169573044 created "2016-06-24" @default.
• W2169573044 creator A5028374451 @default.
• W2169573044 creator A5049111532 @default.
• W2169573044 creator A5063844723 @default.
• W2169573044 creator A5066978144 @default.
• W2169573044 date "2011-07-18" @default.
• W2169573044 modified "2023-10-17" @default.
• W2169573044 title "A population-based study of long-term outcome of epilepsy in childhood with a focal or hemispheric lesion on neuroimaging" @default.
• W2169573044 cites W1502542297 @default.
• W2169573044 cites W1974754818 @default.
• W2169573044 cites W1974809694 @default.
• W2169573044 cites W1981853766 @default.
• W2169573044 cites W1982603580 @default.
• W2169573044 cites W1988280863 @default.
• W2169573044 cites W1994065275 @default.
• W2169573044 cites W2040114219 @default.
• W2169573044 cites W2048327206 @default.
• W2169573044 cites W2049800034 @default.
• W2169573044 cites W2053019231 @default.
• W2169573044 cites W2057836110 @default.
• W2169573044 cites W2070748288 @default.
• W2169573044 cites W2074904157 @default.
• W2169573044 cites W2075725226 @default.
• W2169573044 cites W2085641499 @default.
• W2169573044 cites W2096695182 @default.
• W2169573044 cites W2102430048 @default.
• W2169573044 cites W2114776162 @default.
• W2169573044 cites W2138729862 @default.
• W2169573044 cites W2167993924 @default.
• W2169573044 cites W2326514561 @default.
• W2169573044 cites W4248307879 @default.
• W2169573044 doi "https://doi.org/10.1111/j.1528-1167.2011.03192.x" @default.
• W2169573044 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3244832" @default.
• W2169573044 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21762438" @default.
• W2169573044 hasPublicationYear "2011" @default.
• W2169573044 type Work @default.
• W2169573044 sameAs 2169573044 @default.
• W2169573044 citedByCount "31" @default.
• W2169573044 countsByYear W21695730442013 @default.
• W2169573044 countsByYear W21695730442014 @default.
• W2169573044 countsByYear W21695730442015 @default.
• W2169573044 countsByYear W21695730442017 @default.
• W2169573044 countsByYear W21695730442018 @default.
• W2169573044 countsByYear W21695730442019 @default.
• W2169573044 countsByYear W21695730442021 @default.
• W2169573044 countsByYear W21695730442022 @default.
• W2169573044 countsByYear W21695730442023 @default.
• W2169573044 crossrefType "journal-article" @default.
• W2169573044 hasAuthorship W2169573044A5028374451 @default.
• W2169573044 hasAuthorship W2169573044A5049111532 @default.
• W2169573044 hasAuthorship W2169573044A5063844723 @default.
• W2169573044 hasAuthorship W2169573044A5066978144 @default.
• W2169573044 hasBestOaLocation W21695730442 @default.
• W2169573044 hasConcept C118552586 @default.
• W2169573044 hasConcept C126838900 @default.
• W2169573044 hasConcept C141071460 @default.
• W2169573044 hasConcept C142724271 @default.
• W2169573044 hasConcept C143409427 @default.
• W2169573044 hasConcept C187212893 @default.
• W2169573044 hasConcept C2778186239 @default.
• W2169573044 hasConcept C2778734009 @default.
• W2169573044 hasConcept C2778980267 @default.
• W2169573044 hasConcept C2780803581 @default.
• W2169573044 hasConcept C2781156865 @default.
• W2169573044 hasConcept C2908647359 @default.
• W2169573044 hasConcept C2909225500 @default.
• W2169573044 hasConcept C58693492 @default.
• W2169573044 hasConcept C71924100 @default.
• W2169573044 hasConcept C72563966 @default.
• W2169573044 hasConcept C99454951 @default.
• W2169573044 hasConceptScore W2169573044C118552586 @default.
• W2169573044 hasConceptScore W2169573044C126838900 @default.
• W2169573044 hasConceptScore W2169573044C141071460 @default.
• W2169573044 hasConceptScore W2169573044C142724271 @default.
• W2169573044 hasConceptScore W2169573044C143409427 @default.
• W2169573044 hasConceptScore W2169573044C187212893 @default.
• W2169573044 hasConceptScore W2169573044C2778186239 @default.
• W2169573044 hasConceptScore W2169573044C2778734009 @default.
• W2169573044 hasConceptScore W2169573044C2778980267 @default.
• W2169573044 hasConceptScore W2169573044C2780803581 @default.
• W2169573044 hasConceptScore W2169573044C2781156865 @default.
• W2169573044 hasConceptScore W2169573044C2908647359 @default.
• W2169573044 hasConceptScore W2169573044C2909225500 @default.
• W2169573044 hasConceptScore W2169573044C58693492 @default.
• W2169573044 hasConceptScore W2169573044C71924100 @default.
• W2169573044 hasConceptScore W2169573044C72563966 @default.
• W2169573044 hasConceptScore W2169573044C99454951 @default.
• W2169573044 hasIssue "8" @default.
• W2169573044 hasLocation W21695730441 @default.
• W2169573044 hasLocation W21695730442 @default.
• W2169573044 hasLocation W21695730443 @default.
• W2169573044 hasLocation W21695730444 @default.
• W2169573044 hasOpenAccess W2169573044 @default.
• W2169573044 hasPrimaryLocation W21695730441 @default.
• W2169573044 hasRelatedWork W1952006903 @default.
• W2169573044 hasRelatedWork W2012865524 @default.
• W2169573044 hasRelatedWork W2040816357 @default.

• next