Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169659985> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2169659985 endingPage "1809" @default.
- W2169659985 startingPage "1808" @default.
- W2169659985 abstract "For many patients, a mitochondrial disease diagnosis is often difficult to establish with certainty, except in cases with a classical clinical presentation. Invasive and time-consuming methods, such as tissue biopsy and enzymatic studies, are frequently necessary before proceeding to molecular genetic analyses, because of the low specificity and sensitivity of existing less-invasive biomarkers, such as plasma or CSF lactate, pyruvic acid, or urinary organic acids. Moreover, histologic and biochemical investigation of muscle tissue is often nondiagnostic or may show secondary mitochondrial dysfunction due to aging or medication (e.g., HIV antiviral therapy), even in patients without mitochondrial disease. The introduction of next-generation DNA sequencing with the capability of rapid and simultaneous sequencing of mitochondrial and nuclear encoded genes further reiterates the necessity for a complementary assay with reasonable sensitivity and specificity in order to bypass current invasive testing, such as muscle biopsies." @default.
- W2169659985 created "2016-06-24" @default.
- W2169659985 creator A5036864941 @default.
- W2169659985 creator A5086454854 @default.
- W2169659985 date "2013-10-18" @default.
- W2169659985 modified "2023-10-18" @default.
- W2169659985 title "Fibroblast growth factor 21, a biomarker for mitochondrial muscle disease" @default.
- W2169659985 cites W2000665430 @default.
- W2169659985 cites W2005999729 @default.
- W2169659985 cites W2025139842 @default.
- W2169659985 cites W2047726905 @default.
- W2169659985 cites W2121647203 @default.
- W2169659985 cites W2122185562 @default.
- W2169659985 cites W2131622156 @default.
- W2169659985 cites W2138707492 @default.
- W2169659985 cites W2160416281 @default.
- W2169659985 doi "https://doi.org/10.1212/01.wnl.0000436076.06159.2c" @default.
- W2169659985 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24142478" @default.
- W2169659985 hasPublicationYear "2013" @default.
- W2169659985 type Work @default.
- W2169659985 sameAs 2169659985 @default.
- W2169659985 citedByCount "3" @default.
- W2169659985 countsByYear W21696599852014 @default.
- W2169659985 countsByYear W21696599852015 @default.
- W2169659985 countsByYear W21696599852020 @default.
- W2169659985 crossrefType "journal-article" @default.
- W2169659985 hasAuthorship W2169659985A5036864941 @default.
- W2169659985 hasAuthorship W2169659985A5086454854 @default.
- W2169659985 hasConcept C104317684 @default.
- W2169659985 hasConcept C142724271 @default.
- W2169659985 hasConcept C24586158 @default.
- W2169659985 hasConcept C2775833069 @default.
- W2169659985 hasConcept C2775934546 @default.
- W2169659985 hasConcept C2777614518 @default.
- W2169659985 hasConcept C2779134260 @default.
- W2169659985 hasConcept C2779999465 @default.
- W2169659985 hasConcept C2781197716 @default.
- W2169659985 hasConcept C28859421 @default.
- W2169659985 hasConcept C55493867 @default.
- W2169659985 hasConcept C60644358 @default.
- W2169659985 hasConcept C71924100 @default.
- W2169659985 hasConcept C86803240 @default.
- W2169659985 hasConceptScore W2169659985C104317684 @default.
- W2169659985 hasConceptScore W2169659985C142724271 @default.
- W2169659985 hasConceptScore W2169659985C24586158 @default.
- W2169659985 hasConceptScore W2169659985C2775833069 @default.
- W2169659985 hasConceptScore W2169659985C2775934546 @default.
- W2169659985 hasConceptScore W2169659985C2777614518 @default.
- W2169659985 hasConceptScore W2169659985C2779134260 @default.
- W2169659985 hasConceptScore W2169659985C2779999465 @default.
- W2169659985 hasConceptScore W2169659985C2781197716 @default.
- W2169659985 hasConceptScore W2169659985C28859421 @default.
- W2169659985 hasConceptScore W2169659985C55493867 @default.
- W2169659985 hasConceptScore W2169659985C60644358 @default.
- W2169659985 hasConceptScore W2169659985C71924100 @default.
- W2169659985 hasConceptScore W2169659985C86803240 @default.
- W2169659985 hasIssue "21" @default.
- W2169659985 hasLocation W21696599851 @default.
- W2169659985 hasLocation W21696599852 @default.
- W2169659985 hasOpenAccess W2169659985 @default.
- W2169659985 hasPrimaryLocation W21696599851 @default.
- W2169659985 hasRelatedWork W2043554305 @default.
- W2169659985 hasRelatedWork W2075568923 @default.
- W2169659985 hasRelatedWork W2121075506 @default.
- W2169659985 hasRelatedWork W2146062246 @default.
- W2169659985 hasRelatedWork W2424645153 @default.
- W2169659985 hasRelatedWork W2464158312 @default.
- W2169659985 hasRelatedWork W2471083081 @default.
- W2169659985 hasRelatedWork W2618195533 @default.
- W2169659985 hasRelatedWork W3043574035 @default.
- W2169659985 hasRelatedWork W4211035809 @default.
- W2169659985 hasVolume "81" @default.
- W2169659985 isParatext "false" @default.
- W2169659985 isRetracted "false" @default.
- W2169659985 magId "2169659985" @default.
- W2169659985 workType "article" @default.