Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169666918> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2169666918 endingPage "1618" @default.
- W2169666918 startingPage "1612" @default.
- W2169666918 abstract "A new, simple, specific, accurate and precise reversed phase-high performance liquid chromatography (RP-HPLC) method was developed for the determination of levofloxacin in rat plasma and saliva was developed. An HPLC system based on a Phenomenex Luna C18Column (250 × 4.6 mm) and a UV detector (λ = 296 nm) were used. A mixture of Acetonitrile: water (80:20 v/v) adjusted to pH 3.5 by orthophosphoric acid at a flow rate of 1.4 ml/min was used as mobile phase. The proteins were precipitated with methanol. The average recovery was 94.79 and 92.66%, respectively in plasma and saliva. The detection limit for levofloxacin in plasma and saliva was 1 µg/ml. The calibration curve was linear over the concentration range 1 to 16 mg/ml for plasma and saliva. The inter-day and intra-day assay coefficients of variation were found to be less than 5%. The present validated method was successfully used for pharmacokinetic studies of levofloxacin in plasma and saliva. Key words: High-performance liquid chromatography (HPLC), levofloxacin, plasma, saliva, pharmacokinetics." @default.
- W2169666918 created "2016-06-24" @default.
- W2169666918 creator A5001176238 @default.
- W2169666918 creator A5003034029 @default.
- W2169666918 creator A5015551435 @default.
- W2169666918 creator A5080252247 @default.
- W2169666918 creator A5085395003 @default.
- W2169666918 date "2011-10-08" @default.
- W2169666918 modified "2023-10-01" @default.
- W2169666918 title "Development and validation of RP-HPLC assay for levofloxacin in rat plasma and saliva: Application to pharmacokinetic studies" @default.
- W2169666918 cites W1990079885 @default.
- W2169666918 cites W1995907712 @default.
- W2169666918 cites W2012540684 @default.
- W2169666918 cites W2063445826 @default.
- W2169666918 cites W2069683121 @default.
- W2169666918 cites W2075285876 @default.
- W2169666918 cites W2095926637 @default.
- W2169666918 cites W2101359892 @default.
- W2169666918 cites W2129081916 @default.
- W2169666918 cites W2172139549 @default.
- W2169666918 cites W2182136605 @default.
- W2169666918 cites W2328679708 @default.
- W2169666918 doi "https://doi.org/10.5897/ajpp11.001" @default.
- W2169666918 hasPublicationYear "2011" @default.
- W2169666918 type Work @default.
- W2169666918 sameAs 2169666918 @default.
- W2169666918 citedByCount "5" @default.
- W2169666918 countsByYear W21696669182013 @default.
- W2169666918 countsByYear W21696669182014 @default.
- W2169666918 countsByYear W21696669182023 @default.
- W2169666918 crossrefType "journal-article" @default.
- W2169666918 hasAuthorship W2169666918A5001176238 @default.
- W2169666918 hasAuthorship W2169666918A5003034029 @default.
- W2169666918 hasAuthorship W2169666918A5015551435 @default.
- W2169666918 hasAuthorship W2169666918A5080252247 @default.
- W2169666918 hasAuthorship W2169666918A5085395003 @default.
- W2169666918 hasBestOaLocation W21696669181 @default.
- W2169666918 hasConcept C112705442 @default.
- W2169666918 hasConcept C119128265 @default.
- W2169666918 hasConcept C179998833 @default.
- W2169666918 hasConcept C185592680 @default.
- W2169666918 hasConcept C23531484 @default.
- W2169666918 hasConcept C2781276175 @default.
- W2169666918 hasConcept C43617362 @default.
- W2169666918 hasConcept C501593827 @default.
- W2169666918 hasConcept C504460877 @default.
- W2169666918 hasConcept C55493867 @default.
- W2169666918 hasConcept C71924100 @default.
- W2169666918 hasConcept C98274493 @default.
- W2169666918 hasConceptScore W2169666918C112705442 @default.
- W2169666918 hasConceptScore W2169666918C119128265 @default.
- W2169666918 hasConceptScore W2169666918C179998833 @default.
- W2169666918 hasConceptScore W2169666918C185592680 @default.
- W2169666918 hasConceptScore W2169666918C23531484 @default.
- W2169666918 hasConceptScore W2169666918C2781276175 @default.
- W2169666918 hasConceptScore W2169666918C43617362 @default.
- W2169666918 hasConceptScore W2169666918C501593827 @default.
- W2169666918 hasConceptScore W2169666918C504460877 @default.
- W2169666918 hasConceptScore W2169666918C55493867 @default.
- W2169666918 hasConceptScore W2169666918C71924100 @default.
- W2169666918 hasConceptScore W2169666918C98274493 @default.
- W2169666918 hasIssue "13" @default.
- W2169666918 hasLocation W21696669181 @default.
- W2169666918 hasOpenAccess W2169666918 @default.
- W2169666918 hasPrimaryLocation W21696669181 @default.
- W2169666918 hasRelatedWork W1913148260 @default.
- W2169666918 hasRelatedWork W2006820847 @default.
- W2169666918 hasRelatedWork W2017455098 @default.
- W2169666918 hasRelatedWork W2026619427 @default.
- W2169666918 hasRelatedWork W2063401993 @default.
- W2169666918 hasRelatedWork W2075159353 @default.
- W2169666918 hasRelatedWork W2078048514 @default.
- W2169666918 hasRelatedWork W2162511888 @default.
- W2169666918 hasRelatedWork W2382960470 @default.
- W2169666918 hasRelatedWork W2588622224 @default.
- W2169666918 hasVolume "5" @default.
- W2169666918 isParatext "false" @default.
- W2169666918 isRetracted "false" @default.
- W2169666918 magId "2169666918" @default.
- W2169666918 workType "article" @default.