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- W2169719363 abstract "Polycomb-mediated chromatin repression modulates gene expression during development in metazoans. Binding of multiple sequence-specific factors at discrete Polycomb response elements (PREs) is thought to recruit repressive complexes that spread across an extended chromatin domain. To dissect the structure of PREs, we applied high-resolution mapping of nonhistone chromatin proteins in native chromatin of Drosophila cells. Analysis of occupied sites reveal interactions between transcription factors that stabilize Polycomb anchoring to DNA, and implicate the general transcription factor ADF1 as a novel PRE component. By comparing two Drosophila cell lines with differential chromatin states, we provide evidence that repression is accomplished by enhanced Polycomb recruitment both to PREs and to target promoters of repressed genes. These results suggest that the stability of multifactor complexes at promoters and regulatory elements is a crucial aspect of developmentally regulated gene expression." @default.
- W2169719363 created "2016-06-24" @default.
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- W2169719363 creator A5058508433 @default.
- W2169719363 creator A5078136865 @default.
- W2169719363 creator A5078812290 @default.
- W2169719363 date "2014-03-25" @default.
- W2169719363 modified "2023-10-18" @default.
- W2169719363 title "High-resolution mapping defines the cooperative architecture of Polycomb response elements" @default.
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- W2169719363 cites W1956344811 @default.
- W2169719363 cites W1970709003 @default.
- W2169719363 cites W1973534367 @default.
- W2169719363 cites W1975372081 @default.
- W2169719363 cites W1975992663 @default.
- W2169719363 cites W1978139037 @default.
- W2169719363 cites W1985567287 @default.
- W2169719363 cites W1991442937 @default.
- W2169719363 cites W1992224549 @default.
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- W2169719363 doi "https://doi.org/10.1101/gr.163642.113" @default.
- W2169719363 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4009610" @default.
- W2169719363 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24668908" @default.
- W2169719363 hasPublicationYear "2014" @default.
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