Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169746746> ?p ?o ?g. }
- W2169746746 endingPage "135" @default.
- W2169746746 startingPage "129" @default.
- W2169746746 abstract "Abstract Plasma phospholipid transfer protein (PLTP) mediates both net transfer and exchange of phospholipids between different lipoproteins. Animal studies have shown that it is closely related to the development of atherosclerosis. Although many studies have indicated that PLTP activity is increased in diabetes mellitus, the role of PLTP in diabetes is still unclear. To evaluate the influence of a high‐fat meal on PLTP activity, 50 nondiabetic patients with coronary heart disease (CHD), 50 insulin‐treated Type 2 diabetics, and 50 healthy controls were included. We determined PLTP activity before and 4 and 8 h after a high‐fat meal. As expected, serum PLTP activity was significantly higher in CHD patients than in healthy controls (71.0 ± 46.2 vs. 54.0 ± 33.8 pmol/μl/h, P = 0.032) at baseline. More importantly, we found that serum PLTP activity increased to its maximum 4 h after fat loading and then decreased to nearly basal levels after 8 h both in controls and CHD patients. In contrast, PLTP activity continuously increased during this time period in the diabetic patients. With regards to the data from this study we hypothesize that serum PLTP is involved in the clearance of postprandial lipoproteins and this process is attenuated in diabetes. Since postprandial lipoproteins are atherogenic, the delay in clearance of these particles could play an important role in the development of atherosclerosis in patients with diabetes mellitus." @default.
- W2169746746 created "2016-06-24" @default.
- W2169746746 creator A5010235945 @default.
- W2169746746 creator A5011285126 @default.
- W2169746746 creator A5015285660 @default.
- W2169746746 creator A5029788641 @default.
- W2169746746 creator A5033406476 @default.
- W2169746746 creator A5056517510 @default.
- W2169746746 creator A5065582421 @default.
- W2169746746 creator A5068372200 @default.
- W2169746746 creator A5068544067 @default.
- W2169746746 creator A5070006952 @default.
- W2169746746 creator A5075174977 @default.
- W2169746746 date "2010-01-27" @default.
- W2169746746 modified "2023-10-15" @default.
- W2169746746 title "Serum Phospholipid Transfer Protein Activity After a High Fat Meal in Patients with Insulin-Treated Type 2 Diabetes" @default.
- W2169746746 cites W1551851929 @default.
- W2169746746 cites W1963337827 @default.
- W2169746746 cites W1969379932 @default.
- W2169746746 cites W1978396895 @default.
- W2169746746 cites W2011656212 @default.
- W2169746746 cites W2015662647 @default.
- W2169746746 cites W2026527178 @default.
- W2169746746 cites W2037528870 @default.
- W2169746746 cites W2053201228 @default.
- W2169746746 cites W2107804609 @default.
- W2169746746 cites W2112046710 @default.
- W2169746746 cites W2116090305 @default.
- W2169746746 cites W2124512857 @default.
- W2169746746 cites W2129775374 @default.
- W2169746746 cites W2130245663 @default.
- W2169746746 cites W2131740775 @default.
- W2169746746 cites W2134428736 @default.
- W2169746746 cites W2136431834 @default.
- W2169746746 cites W2136835251 @default.
- W2169746746 cites W2137850214 @default.
- W2169746746 cites W2139356538 @default.
- W2169746746 cites W2153066298 @default.
- W2169746746 cites W2156556864 @default.
- W2169746746 cites W2163518354 @default.
- W2169746746 cites W2181591202 @default.
- W2169746746 cites W2182225386 @default.
- W2169746746 cites W2182787078 @default.
- W2169746746 cites W2331274940 @default.
- W2169746746 cites W4256592710 @default.
- W2169746746 cites W86959576 @default.
- W2169746746 doi "https://doi.org/10.1007/s11745-010-3384-5" @default.
- W2169746746 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20108050" @default.
- W2169746746 hasPublicationYear "2010" @default.
- W2169746746 type Work @default.
- W2169746746 sameAs 2169746746 @default.
- W2169746746 citedByCount "2" @default.
- W2169746746 countsByYear W21697467462019 @default.
- W2169746746 crossrefType "journal-article" @default.
- W2169746746 hasAuthorship W2169746746A5010235945 @default.
- W2169746746 hasAuthorship W2169746746A5011285126 @default.
- W2169746746 hasAuthorship W2169746746A5015285660 @default.
- W2169746746 hasAuthorship W2169746746A5029788641 @default.
- W2169746746 hasAuthorship W2169746746A5033406476 @default.
- W2169746746 hasAuthorship W2169746746A5056517510 @default.
- W2169746746 hasAuthorship W2169746746A5065582421 @default.
- W2169746746 hasAuthorship W2169746746A5068372200 @default.
- W2169746746 hasAuthorship W2169746746A5068544067 @default.
- W2169746746 hasAuthorship W2169746746A5070006952 @default.
- W2169746746 hasAuthorship W2169746746A5075174977 @default.
- W2169746746 hasConcept C126322002 @default.
- W2169746746 hasConcept C134018914 @default.
- W2169746746 hasConcept C185592680 @default.
- W2169746746 hasConcept C22894154 @default.
- W2169746746 hasConcept C2776081396 @default.
- W2169746746 hasConcept C2777180221 @default.
- W2169746746 hasConcept C2778024521 @default.
- W2169746746 hasConcept C2778199505 @default.
- W2169746746 hasConcept C2778345441 @default.
- W2169746746 hasConcept C2778918659 @default.
- W2169746746 hasConcept C2779306644 @default.
- W2169746746 hasConcept C382228 @default.
- W2169746746 hasConcept C41625074 @default.
- W2169746746 hasConcept C55493867 @default.
- W2169746746 hasConcept C555293320 @default.
- W2169746746 hasConcept C71924100 @default.
- W2169746746 hasConceptScore W2169746746C126322002 @default.
- W2169746746 hasConceptScore W2169746746C134018914 @default.
- W2169746746 hasConceptScore W2169746746C185592680 @default.
- W2169746746 hasConceptScore W2169746746C22894154 @default.
- W2169746746 hasConceptScore W2169746746C2776081396 @default.
- W2169746746 hasConceptScore W2169746746C2777180221 @default.
- W2169746746 hasConceptScore W2169746746C2778024521 @default.
- W2169746746 hasConceptScore W2169746746C2778199505 @default.
- W2169746746 hasConceptScore W2169746746C2778345441 @default.
- W2169746746 hasConceptScore W2169746746C2778918659 @default.
- W2169746746 hasConceptScore W2169746746C2779306644 @default.
- W2169746746 hasConceptScore W2169746746C382228 @default.
- W2169746746 hasConceptScore W2169746746C41625074 @default.
- W2169746746 hasConceptScore W2169746746C55493867 @default.
- W2169746746 hasConceptScore W2169746746C555293320 @default.
- W2169746746 hasConceptScore W2169746746C71924100 @default.
- W2169746746 hasIssue "2" @default.