FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169771834> ?p ?o ?g. }

• W2169771834 endingPage "542" @default.
• W2169771834 startingPage "535" @default.
• W2169771834 abstract "Two protein subunits (42,000 and 78,000 daltons) encoded by the fadAB genes form a multifunctional enzyme complex containing thiolase, 3-hydroxyacyl-coenzyme A dehydrogenase, crotonase , epimerase, and isomerase activities (S. Pawar and H. Schulz, J. Biol. Chem. 256:3894-3899, 1981). In an attempt to characterize the structural organization and regulatory properties of these genes, a 5.2-kilobase pair fragment containing the fadAB genes has been isolated. Plasmids containing this fragment (i) complement mutations in the fadAB genes; (ii) overproduce by 10- to 50-fold thiolase, 3-hydroxyacyl-coenzyme A dehydrogenase and crotonase ; and (iii) specify a 42,000- and a 78,000-dalton protein. The fadA gene, which encodes the 42,000-dalton protein, has been localized within the original clone to a 3.3-kilobase pair fragment. Thiolase activity, which is encoded by the 42,000-dalton protein, was not observed in the absence of the 78,000-dalton protein, suggesting that an intact complex is required for function. Transposon Tn5 insertional mutagenesis of the cloned fadAB genes has demonstrated that both fadA and fadB are transcribed as a single transcriptional unit with the direction of transcription from fadA to fadB . The molecular cloning and characterization of the fadAB region confirm the original genetic contention that the genes encoding the proteins for the multifunctional complex form an operon." @default.
• W2169771834 created "2016-06-24" @default.
• W2169771834 creator A5013765814 @default.
• W2169771834 creator A5022199683 @default.
• W2169771834 creator A5059573023 @default.
• W2169771834 creator A5076605396 @default.
• W2169771834 date "1984-05-01" @default.
• W2169771834 modified "2023-09-24" @default.
• W2169771834 title "Cloning, mapping, and expression of genes involved in the fatty acid-degradative multienzyme complex of Escherichia coli" @default.
• W2169771834 cites W1480025162 @default.
• W2169771834 cites W1483028287 @default.
• W2169771834 cites W1492813001 @default.
• W2169771834 cites W1504883942 @default.
• W2169771834 cites W1543086202 @default.
• W2169771834 cites W1569330726 @default.
• W2169771834 cites W1600718860 @default.
• W2169771834 cites W1775749144 @default.
• W2169771834 cites W1820688811 @default.
• W2169771834 cites W1843016560 @default.
• W2169771834 cites W1884756073 @default.
• W2169771834 cites W1894520368 @default.
• W2169771834 cites W1970597174 @default.
• W2169771834 cites W1972671967 @default.
• W2169771834 cites W1983634654 @default.
• W2169771834 cites W1991328593 @default.
• W2169771834 cites W2012184072 @default.
• W2169771834 cites W2025721255 @default.
• W2169771834 cites W2028030581 @default.
• W2169771834 cites W2032776824 @default.
• W2169771834 cites W2038124483 @default.
• W2169771834 cites W2050077441 @default.
• W2169771834 cites W2132481027 @default.
• W2169771834 cites W2135906727 @default.
• W2169771834 cites W2141653906 @default.
• W2169771834 cites W2161524167 @default.
• W2169771834 cites W2917306428 @default.
• W2169771834 cites W4296765338 @default.
• W2169771834 doi "https://doi.org/10.1128/jb.158.2.535-542.1984" @default.
• W2169771834 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/215462" @default.
• W2169771834 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6144665" @default.
• W2169771834 hasPublicationYear "1984" @default.
• W2169771834 type Work @default.
• W2169771834 sameAs 2169771834 @default.
• W2169771834 citedByCount "39" @default.
• W2169771834 countsByYear W21697718342020 @default.
• W2169771834 countsByYear W21697718342021 @default.
• W2169771834 crossrefType "journal-article" @default.
• W2169771834 hasAuthorship W2169771834A5013765814 @default.
• W2169771834 hasAuthorship W2169771834A5022199683 @default.
• W2169771834 hasAuthorship W2169771834A5059573023 @default.
• W2169771834 hasAuthorship W2169771834A5076605396 @default.
• W2169771834 hasBestOaLocation W21697718341 @default.
• W2169771834 hasConcept C104317684 @default.
• W2169771834 hasConcept C127078168 @default.
• W2169771834 hasConcept C143065580 @default.
• W2169771834 hasConcept C150194340 @default.
• W2169771834 hasConcept C153911025 @default.
• W2169771834 hasConcept C19924922 @default.
• W2169771834 hasConcept C203075996 @default.
• W2169771834 hasConcept C22744801 @default.
• W2169771834 hasConcept C2781031557 @default.
• W2169771834 hasConcept C28693550 @default.
• W2169771834 hasConcept C4918238 @default.
• W2169771834 hasConcept C54355233 @default.
• W2169771834 hasConcept C547475151 @default.
• W2169771834 hasConcept C86803240 @default.
• W2169771834 hasConceptScore W2169771834C104317684 @default.
• W2169771834 hasConceptScore W2169771834C127078168 @default.
• W2169771834 hasConceptScore W2169771834C143065580 @default.
• W2169771834 hasConceptScore W2169771834C150194340 @default.
• W2169771834 hasConceptScore W2169771834C153911025 @default.
• W2169771834 hasConceptScore W2169771834C19924922 @default.
• W2169771834 hasConceptScore W2169771834C203075996 @default.
• W2169771834 hasConceptScore W2169771834C22744801 @default.
• W2169771834 hasConceptScore W2169771834C2781031557 @default.
• W2169771834 hasConceptScore W2169771834C28693550 @default.
• W2169771834 hasConceptScore W2169771834C4918238 @default.
• W2169771834 hasConceptScore W2169771834C54355233 @default.
• W2169771834 hasConceptScore W2169771834C547475151 @default.
• W2169771834 hasConceptScore W2169771834C86803240 @default.
• W2169771834 hasIssue "2" @default.
• W2169771834 hasLocation W21697718341 @default.
• W2169771834 hasLocation W21697718342 @default.
• W2169771834 hasLocation W21697718343 @default.
• W2169771834 hasOpenAccess W2169771834 @default.
• W2169771834 hasPrimaryLocation W21697718341 @default.
• W2169771834 hasRelatedWork W1571771606 @default.
• W2169771834 hasRelatedWork W1927614236 @default.
• W2169771834 hasRelatedWork W2019336262 @default.
• W2169771834 hasRelatedWork W2169771834 @default.
• W2169771834 hasRelatedWork W2411507851 @default.
• W2169771834 hasRelatedWork W2461087574 @default.
• W2169771834 hasRelatedWork W2617942190 @default.
• W2169771834 hasRelatedWork W2951407964 @default.
• W2169771834 hasRelatedWork W4220995072 @default.
• W2169771834 hasRelatedWork W4290369219 @default.
• W2169771834 hasVolume "158" @default.
• W2169771834 isParatext "false" @default.

• next