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- W2169776064 abstract "Summary RNA degradation is a major mechanism of post‐transcriptional control of gene expression. Moreover, the rapid turnover of bacterial mRNAs is central to the fast adaptation of these organisms to changing environmental conditions by the regulation of transcription initiation. In most bacteria, RNA processing and degradation require the concerted action of endo‐ and exoribonucleases. In M olecular M icrobiology , L iu et al . (2014) have analysed RNA processing by polynucleotide phosphorylase, the major 3′–5′ exonuclease in B acillus subtilis . For the first time, they were able to study RNA degradation by this enzyme at single nucleotide resolution. The work provides novel insights into the mechanism by which RNA degradation acts in B . subtilis . Moreover, L iu et al . demonstrate that the post‐transcriptional control of central regulators affects the expression of whole regulons." @default.
- W2169776064 created "2016-06-24" @default.
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- W2169776064 date "2014-09-04" @default.
- W2169776064 modified "2023-10-03" @default.
- W2169776064 title "Caught in the act: RNA-Seq provides novel insights into mRNA degradation" @default.
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- W2169776064 doi "https://doi.org/10.1111/mmi.12769" @default.
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