FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169792359> ?p ?o ?g. }

• W2169792359 endingPage "R1597" @default.
• W2169792359 startingPage "R1588" @default.
• W2169792359 abstract "Optimal conditions were developed for an in organello transcriptional run-on assay using mitochondria isolated from Artemia franciscana embryos to investigate potential regulatory features of RNA synthesis under conditions of anoxia-induced quiescence. Transcription is not dependent on oxidative phosphorylation for maximal activity when exogenous ATP is available. Bona fide transcription products, as assessed by hybridization with specific mitochondrial cDNAs from A. franciscana, are produced in an inhibitor-sensitive manner. Transcription rate measured at pH 7.9 is reduced 80% when pH is lowered to 6.3, a pH range that mimics the in vivo change seen on exposure of embryos to anoxia. The proton sensitivity of mitochondrial RNA synthesis may provide a mechanism to depress this significant energy expenditure during quiescence. The influence of nucleotide concentration on kinetics is complicated by an interdependence among nucleotide species. ATP inhibition observed at subsaturating UTP concentrations is relieved when UTP is at saturating, physiologically relevant levels. Taken together, these data suggest that local (versus nuclear mediated) control is important in dictating mitochondrial transcription during rapid modulations in gene expression, such as those observed under anoxia-induced quiescence." @default.
• W2169792359 created "2016-06-24" @default.
• W2169792359 creator A5011704560 @default.
• W2169792359 creator A5060611561 @default.
• W2169792359 date "1999-12-01" @default.
• W2169792359 modified "2023-09-27" @default.
• W2169792359 title "Regulatory features of transcription in isolated mitochondria from<i>Artemia franciscana</i>embryos" @default.
• W2169792359 cites W146421967 @default.
• W2169792359 cites W1483361087 @default.
• W2169792359 cites W1490579006 @default.
• W2169792359 cites W1765263144 @default.
• W2169792359 cites W1801560648 @default.
• W2169792359 cites W1806724336 @default.
• W2169792359 cites W1942284309 @default.
• W2169792359 cites W1958893488 @default.
• W2169792359 cites W1968192610 @default.
• W2169792359 cites W1973270129 @default.
• W2169792359 cites W1988324913 @default.
• W2169792359 cites W2002662437 @default.
• W2169792359 cites W2025627326 @default.
• W2169792359 cites W2034217588 @default.
• W2169792359 cites W2038187308 @default.
• W2169792359 cites W2045426335 @default.
• W2169792359 cites W2050964462 @default.
• W2169792359 cites W2052953221 @default.
• W2169792359 cites W2053353563 @default.
• W2169792359 cites W2064251984 @default.
• W2169792359 cites W2075477070 @default.
• W2169792359 cites W2076661603 @default.
• W2169792359 cites W2078535509 @default.
• W2169792359 cites W2088568207 @default.
• W2169792359 cites W2095287453 @default.
• W2169792359 cites W2099863071 @default.
• W2169792359 cites W2102131116 @default.
• W2169792359 cites W2118063830 @default.
• W2169792359 cites W2131651601 @default.
• W2169792359 cites W2132545076 @default.
• W2169792359 cites W2186014535 @default.
• W2169792359 doi "https://doi.org/10.1152/ajpregu.1999.277.6.r1588" @default.
• W2169792359 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10600903" @default.
• W2169792359 hasPublicationYear "1999" @default.
• W2169792359 type Work @default.
• W2169792359 sameAs 2169792359 @default.
• W2169792359 citedByCount "9" @default.
• W2169792359 countsByYear W21697923592012 @default.
• W2169792359 countsByYear W21697923592014 @default.
• W2169792359 countsByYear W21697923592021 @default.
• W2169792359 countsByYear W21697923592022 @default.
• W2169792359 crossrefType "journal-article" @default.
• W2169792359 hasAuthorship W2169792359A5011704560 @default.
• W2169792359 hasAuthorship W2169792359A5060611561 @default.
• W2169792359 hasConcept C104317684 @default.
• W2169792359 hasConcept C138885662 @default.
• W2169792359 hasConcept C150194340 @default.
• W2169792359 hasConcept C153911025 @default.
• W2169792359 hasConcept C179926584 @default.
• W2169792359 hasConcept C196843134 @default.
• W2169792359 hasConcept C28859421 @default.
• W2169792359 hasConcept C41895202 @default.
• W2169792359 hasConcept C512185932 @default.
• W2169792359 hasConcept C55493867 @default.
• W2169792359 hasConcept C57600042 @default.
• W2169792359 hasConcept C86339819 @default.
• W2169792359 hasConcept C86803240 @default.
• W2169792359 hasConcept C95444343 @default.
• W2169792359 hasConceptScore W2169792359C104317684 @default.
• W2169792359 hasConceptScore W2169792359C138885662 @default.
• W2169792359 hasConceptScore W2169792359C150194340 @default.
• W2169792359 hasConceptScore W2169792359C153911025 @default.
• W2169792359 hasConceptScore W2169792359C179926584 @default.
• W2169792359 hasConceptScore W2169792359C196843134 @default.
• W2169792359 hasConceptScore W2169792359C28859421 @default.
• W2169792359 hasConceptScore W2169792359C41895202 @default.
• W2169792359 hasConceptScore W2169792359C512185932 @default.
• W2169792359 hasConceptScore W2169792359C55493867 @default.
• W2169792359 hasConceptScore W2169792359C57600042 @default.
• W2169792359 hasConceptScore W2169792359C86339819 @default.
• W2169792359 hasConceptScore W2169792359C86803240 @default.
• W2169792359 hasConceptScore W2169792359C95444343 @default.
• W2169792359 hasIssue "6" @default.
• W2169792359 hasLocation W21697923591 @default.
• W2169792359 hasLocation W21697923592 @default.
• W2169792359 hasOpenAccess W2169792359 @default.
• W2169792359 hasPrimaryLocation W21697923591 @default.
• W2169792359 hasRelatedWork W137365727 @default.
• W2169792359 hasRelatedWork W2009966535 @default.
• W2169792359 hasRelatedWork W2023285574 @default.
• W2169792359 hasRelatedWork W2033853062 @default.
• W2169792359 hasRelatedWork W2037366958 @default.
• W2169792359 hasRelatedWork W2045818454 @default.
• W2169792359 hasRelatedWork W2133486230 @default.
• W2169792359 hasRelatedWork W2371566798 @default.
• W2169792359 hasRelatedWork W34700099 @default.
• W2169792359 hasRelatedWork W4303685456 @default.
• W2169792359 hasVolume "277" @default.
• W2169792359 isParatext "false" @default.
• W2169792359 isRetracted "false" @default.
• W2169792359 magId "2169792359" @default.

• next