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- W2169843849 abstract "AbstractThe known metabolite heteronemin was isolated from the marine sponge Hyrtios reticulata Thiele, using a bioguided fractionation with the enzyme protein farnesyl transferase as a target (IC50 = 3 µM). In contrast, 12-epi-heteronemin, isolated from a related sponge, Hyrtios erecta Keller, did not show any noticeable inhibitory activity.Keywords: : HeteroneminHyrtiosmarine natural productsprotein farnesyl transferasesponges" @default.
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- W2169843849 date "2004-01-01" @default.
- W2169843849 modified "2023-10-15" @default.
- W2169843849 title "Heteronemin as a Protein Farnesyl Transferase Inhibitor" @default.
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- W2169843849 doi "https://doi.org/10.1080/13880200490886120" @default.
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