FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170121276> ?p ?o ?g. }

• W2170121276 endingPage "59" @default.
• W2170121276 startingPage "54" @default.
• W2170121276 abstract "The mass screening (MS) of neuroblastoma has been undertaken in Japan by measuring urinary catecholamine metabolites in infants at the age of 6 months. To clarify the biological characteristics of MS-positive (MS+) tumors in infants and MS-negative (MS−)/late-presenting tumors in young children, metaphase cytogenetic and/or interphase 2-color FISH analyses using terminal 1p and pericentromeric 1q probes were performed on 246 (186 MS+ and 60 MS−) patients with neuroblastomas. The 246 tumors were classified into 4 groups on the basis of the constitution of chromosome 1; 22 tumors had disomy 1 with no 1p deletion (Dis1Norm1p); 41 tumors had disomy 1 or tetrasomy 1, all with the 1p deletion (Dis1Del1p); 164 tumors had trisomy 1, pentasomy 1, or a mixed population of cells with trisomy 1 and cells with tetrasomy 1, none with 1p deletion (Tris1Norm1p); 19 tumors with the same copy numbers of chromosome 1 as the Tris1Norm1p group, had 1p deletion (Tris1Del1p). mycn amplification was absent in the Dis1Norm1p and Tris1Del1p groups, frequent in the Dis1Del1p group (24/41), and rare in the Tris1Norm1p group (3/164) (p < 0.0001). Event-free survival at 5 years was lowest [19.5%; 95% confidence interval (CI), 5.1–33.9] in the Dis1Del1p group, highest in the Tris1Norm1p (96.3%; 95% CI, 93.5–99.2) and Tris1Del1p (94.7%; 95% CI, 84.7–104.8) groups, and intermediate but varied (54.5%; 95% CI, 33.7–75.4) in the Dis1Norm1p group (p < 0.0001). Of the MS+ tumors, 90% were Tris1Norm1p or Tris1Del1p, and 55% of the MS− tumors were Dis1Del1p. The finding that the Dis1Del1p tumors were frequent in MS− but not in MS+ tumors suggests the limited efficacy of the MS program into reducing mortality from neuroblastoma. Int. J. Cancer 80:54–59, 1999. © 1999 Wiley-Liss, Inc." @default.
• W2170121276 created "2016-06-24" @default.
• W2170121276 creator A5003748585 @default.
• W2170121276 creator A5059436010 @default.
• W2170121276 creator A5071226522 @default.
• W2170121276 creator A5076867288 @default.
• W2170121276 creator A5087018417 @default.
• W2170121276 date "1999-01-05" @default.
• W2170121276 modified "2023-09-23" @default.
• W2170121276 title "Disomy 1 with terminal 1 p deletion is frequent in mass-screening-negative/late-presenting neuroblastomas in young children, but not in mass-screening-positive neuroblastomas in infants" @default.
• W2170121276 cites W1832579303 @default.
• W2170121276 cites W1965265115 @default.
• W2170121276 cites W1976656341 @default.
• W2170121276 cites W1987234748 @default.
• W2170121276 cites W1989394869 @default.
• W2170121276 cites W1994076841 @default.
• W2170121276 cites W2012219845 @default.
• W2170121276 cites W2022941129 @default.
• W2170121276 cites W2035402634 @default.
• W2170121276 cites W2042451821 @default.
• W2170121276 cites W2056900501 @default.
• W2170121276 cites W2075740912 @default.
• W2170121276 cites W2076327430 @default.
• W2170121276 cites W2079612777 @default.
• W2170121276 cites W2086226581 @default.
• W2170121276 cites W2100603527 @default.
• W2170121276 cites W2101603147 @default.
• W2170121276 cites W2118681164 @default.
• W2170121276 cites W2132604294 @default.
• W2170121276 cites W2168218956 @default.
• W2170121276 cites W2169722878 @default.
• W2170121276 cites W2171767584 @default.
• W2170121276 cites W2187668060 @default.
• W2170121276 cites W2244393570 @default.
• W2170121276 cites W2326401583 @default.
• W2170121276 cites W4293241248 @default.
• W2170121276 doi "https://doi.org/10.1002/(sici)1097-0215(19990105)80:1<54::aid-ijc11>3.0.co;2-g" @default.
• W2170121276 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9935230" @default.
• W2170121276 hasPublicationYear "1999" @default.
• W2170121276 type Work @default.
• W2170121276 sameAs 2170121276 @default.
• W2170121276 citedByCount "15" @default.
• W2170121276 countsByYear W21701212762014 @default.
• W2170121276 crossrefType "journal-article" @default.
• W2170121276 hasAuthorship W2170121276A5003748585 @default.
• W2170121276 hasAuthorship W2170121276A5059436010 @default.
• W2170121276 hasAuthorship W2170121276A5071226522 @default.
• W2170121276 hasAuthorship W2170121276A5076867288 @default.
• W2170121276 hasAuthorship W2170121276A5087018417 @default.
• W2170121276 hasBestOaLocation W21701212761 @default.
• W2170121276 hasConcept C104317684 @default.
• W2170121276 hasConcept C126322002 @default.
• W2170121276 hasConcept C142724271 @default.
• W2170121276 hasConcept C2776229224 @default.
• W2170121276 hasConcept C2776715637 @default.
• W2170121276 hasConcept C2778249689 @default.
• W2170121276 hasConcept C2779672484 @default.
• W2170121276 hasConcept C2908647359 @default.
• W2170121276 hasConcept C30481170 @default.
• W2170121276 hasConcept C54355233 @default.
• W2170121276 hasConcept C71924100 @default.
• W2170121276 hasConcept C81885089 @default.
• W2170121276 hasConcept C86803240 @default.
• W2170121276 hasConcept C90924648 @default.
• W2170121276 hasConcept C99454951 @default.
• W2170121276 hasConceptScore W2170121276C104317684 @default.
• W2170121276 hasConceptScore W2170121276C126322002 @default.
• W2170121276 hasConceptScore W2170121276C142724271 @default.
• W2170121276 hasConceptScore W2170121276C2776229224 @default.
• W2170121276 hasConceptScore W2170121276C2776715637 @default.
• W2170121276 hasConceptScore W2170121276C2778249689 @default.
• W2170121276 hasConceptScore W2170121276C2779672484 @default.
• W2170121276 hasConceptScore W2170121276C2908647359 @default.
• W2170121276 hasConceptScore W2170121276C30481170 @default.
• W2170121276 hasConceptScore W2170121276C54355233 @default.
• W2170121276 hasConceptScore W2170121276C71924100 @default.
• W2170121276 hasConceptScore W2170121276C81885089 @default.
• W2170121276 hasConceptScore W2170121276C86803240 @default.
• W2170121276 hasConceptScore W2170121276C90924648 @default.
• W2170121276 hasConceptScore W2170121276C99454951 @default.
• W2170121276 hasIssue "1" @default.
• W2170121276 hasLocation W21701212761 @default.
• W2170121276 hasLocation W21701212762 @default.
• W2170121276 hasOpenAccess W2170121276 @default.
• W2170121276 hasPrimaryLocation W21701212761 @default.
• W2170121276 hasRelatedWork W1992897841 @default.
• W2170121276 hasRelatedWork W1992935220 @default.
• W2170121276 hasRelatedWork W2000149062 @default.
• W2170121276 hasRelatedWork W2037552454 @default.
• W2170121276 hasRelatedWork W2039216342 @default.
• W2170121276 hasRelatedWork W2039342645 @default.
• W2170121276 hasRelatedWork W2071114556 @default.
• W2170121276 hasRelatedWork W2085486615 @default.
• W2170121276 hasRelatedWork W2169164598 @default.
• W2170121276 hasRelatedWork W2417636432 @default.
• W2170121276 hasVolume "80" @default.
• W2170121276 isParatext "false" @default.
• W2170121276 isRetracted "false" @default.

• next