Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170302011> ?p ?o ?g. }
- W2170302011 endingPage "2734S" @default.
- W2170302011 startingPage "2728S" @default.
- W2170302011 abstract "Osteoporosis is a major cause of morbidity and mortality through its association with age-related fractures. Although most efforts in fracture prevention have been directed at retarding the rate of age-related bone loss and reducing the frequency and the severity of trauma among elderly people, evidence is growing that peak bone mass is an important contributor to bone strength during later life. The normal patterns of skeletal growth have been well characterized in cross-sectional and longitudinal studies. It has been confirmed that boys have higher bone-mineral content, but not volumetric bone density, than girls. Furthermore, there is a disassociation between the peak velocities for height gain and bone mineral accrual in both genders. Puberty is the period during which volumetric density appears to increase in both axial and appendicular sites. Many factors influence the accumulation of bone mineral during childhood and adolescence, including heredity, gender, diet, physical activity, endocrine status, and sporadic risk factors (e.g., cigarette smoking). In addition to these modifiable factors during childhood, evidence has also accrued that fracture risk might be programmed during intrauterine life. Epidemiological studies have demonstrated a relationship between birthweight, weight in infancy, and adult bone mass. This appears to be mediated through modulation of the set-point for basal activity of endocrine systems such as the GH/IGF-1 and parathyroid hormone/vitamin D axes. Maternal vitamin D insufficiency is associated with reduced bone mineral acquisition during intrauterine and early postnatal life. Furthermore, both low birth size and poor childhood growth are directly linked to the later risk of hip fracture. The optimization of maternal nutrition and intrauterine growth should also be included within preventive strategies against osteoporotic fracture, albeit for future generations." @default.
- W2170302011 created "2016-06-24" @default.
- W2170302011 creator A5047582694 @default.
- W2170302011 creator A5048132322 @default.
- W2170302011 creator A5065164806 @default.
- W2170302011 creator A5068193213 @default.
- W2170302011 creator A5079005099 @default.
- W2170302011 date "2005-11-01" @default.
- W2170302011 modified "2023-10-01" @default.
- W2170302011 title "Developmental Origins of Osteoporotic Fracture: the Role of Maternal Vitamin D Insufficiency" @default.
- W2170302011 cites W1886247043 @default.
- W2170302011 cites W1894533129 @default.
- W2170302011 cites W1967945945 @default.
- W2170302011 cites W1984274121 @default.
- W2170302011 cites W1984593008 @default.
- W2170302011 cites W1986657923 @default.
- W2170302011 cites W2001656238 @default.
- W2170302011 cites W2005416498 @default.
- W2170302011 cites W2029181759 @default.
- W2170302011 cites W2035118995 @default.
- W2170302011 cites W2048013543 @default.
- W2170302011 cites W2072497093 @default.
- W2170302011 cites W2074467897 @default.
- W2170302011 cites W2075153512 @default.
- W2170302011 cites W2082970944 @default.
- W2170302011 cites W2087172428 @default.
- W2170302011 cites W2109183846 @default.
- W2170302011 cites W2118705787 @default.
- W2170302011 cites W2119435706 @default.
- W2170302011 cites W2125089843 @default.
- W2170302011 cites W2126082773 @default.
- W2170302011 cites W2135550286 @default.
- W2170302011 cites W2137148433 @default.
- W2170302011 cites W2148530660 @default.
- W2170302011 cites W2162499454 @default.
- W2170302011 doi "https://doi.org/10.1093/jn/135.11.2728s" @default.
- W2170302011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16251639" @default.
- W2170302011 hasPublicationYear "2005" @default.
- W2170302011 type Work @default.
- W2170302011 sameAs 2170302011 @default.
- W2170302011 citedByCount "89" @default.
- W2170302011 countsByYear W21703020112012 @default.
- W2170302011 countsByYear W21703020112013 @default.
- W2170302011 countsByYear W21703020112014 @default.
- W2170302011 countsByYear W21703020112015 @default.
- W2170302011 countsByYear W21703020112016 @default.
- W2170302011 countsByYear W21703020112017 @default.
- W2170302011 countsByYear W21703020112018 @default.
- W2170302011 countsByYear W21703020112019 @default.
- W2170302011 countsByYear W21703020112020 @default.
- W2170302011 countsByYear W21703020112021 @default.
- W2170302011 countsByYear W21703020112022 @default.
- W2170302011 countsByYear W21703020112023 @default.
- W2170302011 crossrefType "journal-article" @default.
- W2170302011 hasAuthorship W2170302011A5047582694 @default.
- W2170302011 hasAuthorship W2170302011A5048132322 @default.
- W2170302011 hasAuthorship W2170302011A5065164806 @default.
- W2170302011 hasAuthorship W2170302011A5068193213 @default.
- W2170302011 hasAuthorship W2170302011A5079005099 @default.
- W2170302011 hasBestOaLocation W21703020111 @default.
- W2170302011 hasConcept C124490489 @default.
- W2170302011 hasConcept C126322002 @default.
- W2170302011 hasConcept C134018914 @default.
- W2170302011 hasConcept C170033053 @default.
- W2170302011 hasConcept C187212893 @default.
- W2170302011 hasConcept C2776541429 @default.
- W2170302011 hasConcept C2776886416 @default.
- W2170302011 hasConcept C2779329777 @default.
- W2170302011 hasConcept C2780712178 @default.
- W2170302011 hasConcept C2781208988 @default.
- W2170302011 hasConcept C42407357 @default.
- W2170302011 hasConcept C46699223 @default.
- W2170302011 hasConcept C519063684 @default.
- W2170302011 hasConcept C71315377 @default.
- W2170302011 hasConcept C71924100 @default.
- W2170302011 hasConceptScore W2170302011C124490489 @default.
- W2170302011 hasConceptScore W2170302011C126322002 @default.
- W2170302011 hasConceptScore W2170302011C134018914 @default.
- W2170302011 hasConceptScore W2170302011C170033053 @default.
- W2170302011 hasConceptScore W2170302011C187212893 @default.
- W2170302011 hasConceptScore W2170302011C2776541429 @default.
- W2170302011 hasConceptScore W2170302011C2776886416 @default.
- W2170302011 hasConceptScore W2170302011C2779329777 @default.
- W2170302011 hasConceptScore W2170302011C2780712178 @default.
- W2170302011 hasConceptScore W2170302011C2781208988 @default.
- W2170302011 hasConceptScore W2170302011C42407357 @default.
- W2170302011 hasConceptScore W2170302011C46699223 @default.
- W2170302011 hasConceptScore W2170302011C519063684 @default.
- W2170302011 hasConceptScore W2170302011C71315377 @default.
- W2170302011 hasConceptScore W2170302011C71924100 @default.
- W2170302011 hasIssue "11" @default.
- W2170302011 hasLocation W21703020111 @default.
- W2170302011 hasLocation W21703020112 @default.
- W2170302011 hasLocation W21703020113 @default.
- W2170302011 hasOpenAccess W2170302011 @default.
- W2170302011 hasPrimaryLocation W21703020111 @default.
- W2170302011 hasRelatedWork W1984223009 @default.
- W2170302011 hasRelatedWork W2073151133 @default.