FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170306190> ?p ?o ?g. }

• W2170306190 endingPage "2200" @default.
• W2170306190 startingPage "2191" @default.
• W2170306190 abstract "The vinegar fly, Drosophila melanogaster, is a popular model for the study of invertebrate antiviral immune responses. Several picorna-like viruses are commonly found in both wild and laboratory populations of D. melanogaster. The best-studied and most pathogenic of these is the dicistrovirus Drosophila C virus. Among the uncharacterized small RNA viruses of D. melanogaster, Drosophila A virus (DAV) is the least pathogenic. Historically, DAV has been labelled as a picorna-like virus based on its particle size and the content of its RNA genome. Here, we describe the characterization of both the genome and the virion structure of DAV. Unexpectedly, the DAV genome was shown to encode a circular permutation in the palm-domain motifs of the RNA-dependent RNA polymerase. This arrangement has only been described previously for a subset of viruses from the double-stranded RNA virus family Birnaviridae and the T=4 single-stranded RNA virus family Tetraviridae. The 8 A (0.8 nm) DAV virion structure computed from cryo-electron microscopy and image reconstruction indicates that the virus structural protein forms two discrete domains within the capsid. The inner domain is formed from a clear T=3 lattice with similarity to the beta-sandwich domain of tomato bushy stunt virus, whilst the outer domain is not ordered icosahedrally, but forms a cage-like structure that surrounds the core domain. Taken together, this indicates that DAV is highly divergent from previously described viruses." @default.
• W2170306190 created "2016-06-24" @default.
• W2170306190 creator A5012232797 @default.
• W2170306190 creator A5020651944 @default.
• W2170306190 creator A5045621920 @default.
• W2170306190 creator A5059277072 @default.
• W2170306190 creator A5074756255 @default.
• W2170306190 creator A5078724396 @default.
• W2170306190 date "2009-05-27" @default.
• W2170306190 modified "2023-10-18" @default.
• W2170306190 title "Drosophila A virus is an unusual RNA virus with a T=3 icosahedral core and permuted RNA-dependent RNA polymerase" @default.
• W2170306190 cites W112224279 @default.
• W2170306190 cites W1514232196 @default.
• W2170306190 cites W1582561043 @default.
• W2170306190 cites W1590668008 @default.
• W2170306190 cites W1915814871 @default.
• W2170306190 cites W1963686561 @default.
• W2170306190 cites W1969363041 @default.
• W2170306190 cites W1979497301 @default.
• W2170306190 cites W1988723707 @default.
• W2170306190 cites W1995750141 @default.
• W2170306190 cites W1996328423 @default.
• W2170306190 cites W1997149898 @default.
• W2170306190 cites W1998150898 @default.
• W2170306190 cites W2003330861 @default.
• W2170306190 cites W2003756563 @default.
• W2170306190 cites W2006158980 @default.
• W2170306190 cites W2028012273 @default.
• W2170306190 cites W2031040301 @default.
• W2170306190 cites W2037977143 @default.
• W2170306190 cites W2043283675 @default.
• W2170306190 cites W2045665377 @default.
• W2170306190 cites W2048004737 @default.
• W2170306190 cites W2062730064 @default.
• W2170306190 cites W2065832641 @default.
• W2170306190 cites W2066799171 @default.
• W2170306190 cites W2075519966 @default.
• W2170306190 cites W2076449818 @default.
• W2170306190 cites W2092052419 @default.
• W2170306190 cites W2094614903 @default.
• W2170306190 cites W2098727368 @default.
• W2170306190 cites W2106026051 @default.
• W2170306190 cites W2135599501 @default.
• W2170306190 cites W2141673119 @default.
• W2170306190 cites W2141783940 @default.
• W2170306190 cites W2142238693 @default.
• W2170306190 cites W2142355187 @default.
• W2170306190 cites W2143353745 @default.
• W2170306190 cites W2148085578 @default.
• W2170306190 cites W2159746639 @default.
• W2170306190 cites W2161661741 @default.
• W2170306190 cites W2163929959 @default.
• W2170306190 cites W2165990041 @default.
• W2170306190 cites W2170123229 @default.
• W2170306190 cites W2170805027 @default.
• W2170306190 doi "https://doi.org/10.1099/vir.0.012104-0" @default.
• W2170306190 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2742409" @default.
• W2170306190 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19474243" @default.
• W2170306190 hasPublicationYear "2009" @default.
• W2170306190 type Work @default.
• W2170306190 sameAs 2170306190 @default.
• W2170306190 citedByCount "25" @default.
• W2170306190 countsByYear W21703061902012 @default.
• W2170306190 countsByYear W21703061902013 @default.
• W2170306190 countsByYear W21703061902014 @default.
• W2170306190 countsByYear W21703061902015 @default.
• W2170306190 countsByYear W21703061902016 @default.
• W2170306190 countsByYear W21703061902017 @default.
• W2170306190 countsByYear W21703061902018 @default.
• W2170306190 countsByYear W21703061902020 @default.
• W2170306190 countsByYear W21703061902021 @default.
• W2170306190 countsByYear W21703061902022 @default.
• W2170306190 countsByYear W21703061902023 @default.
• W2170306190 crossrefType "journal-article" @default.
• W2170306190 hasAuthorship W2170306190A5012232797 @default.
• W2170306190 hasAuthorship W2170306190A5020651944 @default.
• W2170306190 hasAuthorship W2170306190A5045621920 @default.
• W2170306190 hasAuthorship W2170306190A5059277072 @default.
• W2170306190 hasAuthorship W2170306190A5074756255 @default.
• W2170306190 hasAuthorship W2170306190A5078724396 @default.
• W2170306190 hasBestOaLocation W21703061901 @default.
• W2170306190 hasConcept C104317684 @default.
• W2170306190 hasConcept C141231307 @default.
• W2170306190 hasConcept C159047783 @default.
• W2170306190 hasConcept C202878990 @default.
• W2170306190 hasConcept C2522874641 @default.
• W2170306190 hasConcept C2776449523 @default.
• W2170306190 hasConcept C2779174946 @default.
• W2170306190 hasConcept C2780104201 @default.
• W2170306190 hasConcept C41258723 @default.
• W2170306190 hasConcept C54355233 @default.
• W2170306190 hasConcept C67705224 @default.
• W2170306190 hasConcept C82381507 @default.
• W2170306190 hasConcept C86803240 @default.
• W2170306190 hasConceptScore W2170306190C104317684 @default.
• W2170306190 hasConceptScore W2170306190C141231307 @default.
• W2170306190 hasConceptScore W2170306190C159047783 @default.
• W2170306190 hasConceptScore W2170306190C202878990 @default.

• next