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- W2170333298 abstract "Accumulating evidence indicates that individuals with schizophrenia manifest abnormalities in structures (cerebellum and basal ganglia) and neurotransmitter systems (dopamine) linked to internal-timing processes. A single-cue tone delay eyeblink conditioning paradigm comprised of 100 learning and 50 extinction trials was used to examine cerebellar timing circuits in 13 medicated patients with schizophrenia and 13 age- and sex-matched controls. Patients with schizophrenia showed impaired learning of the conditioned response compared to controls and also greater within-subject variability in the timing of their responses. These findings are consistent with models of schizophrenia in which timing deficits underlie information-processing abnormalities and clinical features of the disorder." @default.
- W2170333298 created "2016-06-24" @default.
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- W2170333298 date "2005-06-01" @default.
- W2170333298 modified "2023-10-13" @default.
- W2170333298 title "Eyeblink conditioning deficits indicate timing and cerebellar abnormalities in schizophrenia" @default.
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