Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170339988> ?p ?o ?g. }
- W2170339988 endingPage "1461" @default.
- W2170339988 startingPage "1451" @default.
- W2170339988 abstract "This study aims to synthesize cost and health outcomes for current treatment pathways for esophageal adenocarcinoma and high-grade dysplasia (HGD) and to model comparative net clinical and economic benefits of alternative management scenarios. A decision-analytic model of real-world practices for esophageal adenocarcinoma treatment by tumor stage was constructed and validated. The model synthesized treatment probabilities, survival, quality of life, and resource use extracted from epidemiological datasets, published literature, and expert opinion. Comparative analyses between current practice and five hypothetical scenarios for modified treatment were undertaken. Over 5 years, outcomes across T stage ranged from 4.06 quality-adjusted life-years and costs of $3,179 for HGD to 1.62 quality-adjusted life-years and costs of $50,226 for stage T4. Greater use of endoscopic mucosal resection for stage T1 and measures to reduce esophagectomy mortality to 0–3 % produced modest gains, whereas a 20 % reduction in the proportion of patients presenting at stage T3 produced large incremental net benefits of $4,971 (95 % interval, $1,560–8,368). These findings support measures that promote earlier diagnosis, such as developing risk assessment processes or endoscopic surveillance of Barrett’s esophagus. Incremental net monetary benefits for other strategies are relatively small in comparison to predicted gains from early detection strategies." @default.
- W2170339988 created "2016-06-24" @default.
- W2170339988 creator A5002993982 @default.
- W2170339988 creator A5006227775 @default.
- W2170339988 creator A5013708960 @default.
- W2170339988 creator A5018743654 @default.
- W2170339988 creator A5027765428 @default.
- W2170339988 creator A5031709820 @default.
- W2170339988 creator A5037878324 @default.
- W2170339988 creator A5047913945 @default.
- W2170339988 creator A5059001354 @default.
- W2170339988 creator A5072607971 @default.
- W2170339988 date "2012-05-30" @default.
- W2170339988 modified "2023-10-17" @default.
- W2170339988 title "Modeling the Cost-effectiveness of Strategies for Treating Esophageal Adenocarcinoma and High-grade Dysplasia" @default.
- W2170339988 cites W1531867301 @default.
- W2170339988 cites W1540633002 @default.
- W2170339988 cites W1616427490 @default.
- W2170339988 cites W1846128085 @default.
- W2170339988 cites W1974058354 @default.
- W2170339988 cites W1975320457 @default.
- W2170339988 cites W1975939084 @default.
- W2170339988 cites W1975962137 @default.
- W2170339988 cites W1982997453 @default.
- W2170339988 cites W1983800857 @default.
- W2170339988 cites W1990750850 @default.
- W2170339988 cites W1997683073 @default.
- W2170339988 cites W2011223700 @default.
- W2170339988 cites W202350784 @default.
- W2170339988 cites W2024398404 @default.
- W2170339988 cites W2035531865 @default.
- W2170339988 cites W2037640584 @default.
- W2170339988 cites W2050669610 @default.
- W2170339988 cites W2061472128 @default.
- W2170339988 cites W2062340807 @default.
- W2170339988 cites W2087152701 @default.
- W2170339988 cites W2091434509 @default.
- W2170339988 cites W2094575985 @default.
- W2170339988 cites W2113332568 @default.
- W2170339988 cites W2120450267 @default.
- W2170339988 cites W2125468171 @default.
- W2170339988 cites W2140709858 @default.
- W2170339988 cites W2141147516 @default.
- W2170339988 cites W2145440884 @default.
- W2170339988 cites W2149049271 @default.
- W2170339988 cites W2163478677 @default.
- W2170339988 cites W2614452305 @default.
- W2170339988 cites W1988187289 @default.
- W2170339988 doi "https://doi.org/10.1007/s11605-012-1911-9" @default.
- W2170339988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22644445" @default.
- W2170339988 hasPublicationYear "2012" @default.
- W2170339988 type Work @default.
- W2170339988 sameAs 2170339988 @default.
- W2170339988 citedByCount "10" @default.
- W2170339988 countsByYear W21703399882012 @default.
- W2170339988 countsByYear W21703399882013 @default.
- W2170339988 countsByYear W21703399882014 @default.
- W2170339988 countsByYear W21703399882016 @default.
- W2170339988 countsByYear W21703399882019 @default.
- W2170339988 countsByYear W21703399882020 @default.
- W2170339988 countsByYear W21703399882021 @default.
- W2170339988 countsByYear W21703399882022 @default.
- W2170339988 crossrefType "journal-article" @default.
- W2170339988 hasAuthorship W2170339988A5002993982 @default.
- W2170339988 hasAuthorship W2170339988A5006227775 @default.
- W2170339988 hasAuthorship W2170339988A5013708960 @default.
- W2170339988 hasAuthorship W2170339988A5018743654 @default.
- W2170339988 hasAuthorship W2170339988A5027765428 @default.
- W2170339988 hasAuthorship W2170339988A5031709820 @default.
- W2170339988 hasAuthorship W2170339988A5037878324 @default.
- W2170339988 hasAuthorship W2170339988A5047913945 @default.
- W2170339988 hasAuthorship W2170339988A5059001354 @default.
- W2170339988 hasAuthorship W2170339988A5072607971 @default.
- W2170339988 hasBestOaLocation W21703399882 @default.
- W2170339988 hasConcept C112930515 @default.
- W2170339988 hasConcept C121608353 @default.
- W2170339988 hasConcept C126322002 @default.
- W2170339988 hasConcept C127454912 @default.
- W2170339988 hasConcept C141071460 @default.
- W2170339988 hasConcept C146357865 @default.
- W2170339988 hasConcept C151730666 @default.
- W2170339988 hasConcept C159110408 @default.
- W2170339988 hasConcept C159110652 @default.
- W2170339988 hasConcept C177713679 @default.
- W2170339988 hasConcept C18903297 @default.
- W2170339988 hasConcept C2775894508 @default.
- W2170339988 hasConcept C2777297899 @default.
- W2170339988 hasConcept C2777819096 @default.
- W2170339988 hasConcept C2778589982 @default.
- W2170339988 hasConcept C2778866283 @default.
- W2170339988 hasConcept C2779742542 @default.
- W2170339988 hasConcept C2779951463 @default.
- W2170339988 hasConcept C2781182431 @default.
- W2170339988 hasConcept C2992824209 @default.
- W2170339988 hasConcept C3019080777 @default.
- W2170339988 hasConcept C61434518 @default.
- W2170339988 hasConcept C64332521 @default.
- W2170339988 hasConcept C71924100 @default.