FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170442080> ?p ?o ?g. }

• W2170442080 endingPage "563" @default.
• W2170442080 startingPage "555" @default.
• W2170442080 abstract "Helicobacter pylori are found attached to mucous cells of the human stomach or under the mucous layer. Models mimicking the in vivo situation may be more suitable for H. pylori MIC determinations than traditional agar dilution methods. Megraud et al. (Antimicrobial Agents and Chemotherapy 1991, 35, 869-72) developed a model for measuring the susceptibility of attached and free-floating H. pylori. We have modified this model so that free-floating and attached H. pylori are treated in a more similar manner, before and after incubation with antibiotic, and performed additional controls to ensure H. pylori and tissue culture cells are not detrimentally affected and maintain their viability during the course of the experiment. We found only 10% of plate-grown H. pylori were competent for attachment to HEp-2 cells; however, all progeny of attached bacteria remained adherent. Killing curves were performed using 0, 0.001, 0.01, 0.1 and 1 mg/L amoxycillin, and 0, 0.0025, 0.0075 and 0.01 mg/L clarithromycin. H. pylori divided at concentrations <or= 0.01 mg/L amoxycillin and <or= 0.0025 mg/L clarithromycin. Contrary to the previous study, using our modified method we found that HEp-2 adherent and freefloating H. pylori are equally susceptible to amoxycillin (strains 26695, CCUG18943, CCUG19104 and CCUG19110) and clarithromycin (strain 26695). Therefore, we find no evidence that attachment of H. pylori to eukaryotic cells increases their resistance to antibiotics compared with non-attached bacteria. Nonetheless, these results confirm confidence in traditional MIC studies when a comparison is made between susceptible and resistant strains." @default.
• W2170442080 created "2016-06-24" @default.
• W2170442080 creator A5025128459 @default.
• W2170442080 creator A5032739826 @default.
• W2170442080 creator A5082599033 @default.
• W2170442080 date "2001-05-01" @default.
• W2170442080 modified "2023-09-25" @default.
• W2170442080 title "Antibiotic susceptibility of attached and free-floating Helicobacter pylori" @default.
• W2170442080 cites W1479934902 @default.
• W2170442080 cites W1556827131 @default.
• W2170442080 cites W1834561419 @default.
• W2170442080 cites W1866505955 @default.
• W2170442080 cites W1901292304 @default.
• W2170442080 cites W1961845583 @default.
• W2170442080 cites W196341856 @default.
• W2170442080 cites W1972895147 @default.
• W2170442080 cites W1976955035 @default.
• W2170442080 cites W1979025459 @default.
• W2170442080 cites W1989942039 @default.
• W2170442080 cites W1991447989 @default.
• W2170442080 cites W1997889971 @default.
• W2170442080 cites W2007522297 @default.
• W2170442080 cites W2007807400 @default.
• W2170442080 cites W2012994521 @default.
• W2170442080 cites W2024651025 @default.
• W2170442080 cites W2040627002 @default.
• W2170442080 cites W2041805992 @default.
• W2170442080 cites W2053218002 @default.
• W2170442080 cites W2069403541 @default.
• W2170442080 cites W2079786242 @default.
• W2170442080 cites W2079974592 @default.
• W2170442080 cites W2082718174 @default.
• W2170442080 cites W2083036025 @default.
• W2170442080 cites W2087544226 @default.
• W2170442080 cites W2099007595 @default.
• W2170442080 cites W2101571688 @default.
• W2170442080 cites W2104116747 @default.
• W2170442080 cites W2114619963 @default.
• W2170442080 cites W2116048546 @default.
• W2170442080 cites W2120464057 @default.
• W2170442080 cites W2124970554 @default.
• W2170442080 cites W2128506712 @default.
• W2170442080 cites W2137118229 @default.
• W2170442080 cites W2152586977 @default.
• W2170442080 cites W2153759308 @default.
• W2170442080 cites W2188190921 @default.
• W2170442080 cites W4244949868 @default.
• W2170442080 doi "https://doi.org/10.1093/jac/47.5.555" @default.
• W2170442080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11328765" @default.
• W2170442080 hasPublicationYear "2001" @default.
• W2170442080 type Work @default.
• W2170442080 sameAs 2170442080 @default.
• W2170442080 citedByCount "10" @default.
• W2170442080 countsByYear W21704420802014 @default.
• W2170442080 countsByYear W21704420802016 @default.
• W2170442080 countsByYear W21704420802022 @default.
• W2170442080 countsByYear W21704420802023 @default.
• W2170442080 crossrefType "journal-article" @default.
• W2170442080 hasAuthorship W2170442080A5025128459 @default.
• W2170442080 hasAuthorship W2170442080A5032739826 @default.
• W2170442080 hasAuthorship W2170442080A5082599033 @default.
• W2170442080 hasConcept C176947019 @default.
• W2170442080 hasConcept C207001950 @default.
• W2170442080 hasConcept C25642318 @default.
• W2170442080 hasConcept C2776409635 @default.
• W2170442080 hasConcept C2776962512 @default.
• W2170442080 hasConcept C2778660310 @default.
• W2170442080 hasConcept C2779708577 @default.
• W2170442080 hasConcept C2780493024 @default.
• W2170442080 hasConcept C3019249092 @default.
• W2170442080 hasConcept C4937899 @default.
• W2170442080 hasConcept C501593827 @default.
• W2170442080 hasConcept C523546767 @default.
• W2170442080 hasConcept C54355233 @default.
• W2170442080 hasConcept C55493867 @default.
• W2170442080 hasConcept C62643968 @default.
• W2170442080 hasConcept C86803240 @default.
• W2170442080 hasConcept C89423630 @default.
• W2170442080 hasConceptScore W2170442080C176947019 @default.
• W2170442080 hasConceptScore W2170442080C207001950 @default.
• W2170442080 hasConceptScore W2170442080C25642318 @default.
• W2170442080 hasConceptScore W2170442080C2776409635 @default.
• W2170442080 hasConceptScore W2170442080C2776962512 @default.
• W2170442080 hasConceptScore W2170442080C2778660310 @default.
• W2170442080 hasConceptScore W2170442080C2779708577 @default.
• W2170442080 hasConceptScore W2170442080C2780493024 @default.
• W2170442080 hasConceptScore W2170442080C3019249092 @default.
• W2170442080 hasConceptScore W2170442080C4937899 @default.
• W2170442080 hasConceptScore W2170442080C501593827 @default.
• W2170442080 hasConceptScore W2170442080C523546767 @default.
• W2170442080 hasConceptScore W2170442080C54355233 @default.
• W2170442080 hasConceptScore W2170442080C55493867 @default.
• W2170442080 hasConceptScore W2170442080C62643968 @default.
• W2170442080 hasConceptScore W2170442080C86803240 @default.
• W2170442080 hasConceptScore W2170442080C89423630 @default.
• W2170442080 hasIssue "5" @default.
• W2170442080 hasLocation W21704420801 @default.
• W2170442080 hasLocation W21704420802 @default.

• next