FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170455802> ?p ?o ?g. }

• W2170455802 endingPage "681" @default.
• W2170455802 startingPage "668" @default.
• W2170455802 abstract "Faithful duplication of the genome relies on the ability to cope with an imperfect template. We investigated replication of UV-damaged DNA in Escherichia coli and found that ongoing replication stops for at least 15-20 min before resuming. Undamaged origins of replication (oriC) continue to fire at the normal rate and in a DnaA-dependent manner. UV irradiation also induces substantial DnaA-independent replication. These two factors add substantially to the DNA synthesis detected after irradiation and together mask the delay in the progression of pre-existing forks in assays measuring net synthesis. All DNA synthesis after UV depends on DnaC, implying that replication restart of blocked forks requires DnaB loading and possibly the entire assembly of new replisomes. Restart appears to occur synchronously when most lesions have been removed. This raises the possibility that restart and lesion removal are coupled. Both restart and cell division suffer long delays if lesion removal is prevented, but restart can occur. Our data fit well with models invoking the stalling of replication forks and their extensive processing before replication can restart. Delayed restart avoids the dangers of excessive recombination that might result if forks skipped over lesion after lesion, leaving many gaps in their wake." @default.
• W2170455802 created "2016-06-24" @default.
• W2170455802 creator A5000430518 @default.
• W2170455802 creator A5025661928 @default.
• W2170455802 creator A5033424893 @default.
• W2170455802 date "2007-03-15" @default.
• W2170455802 modified "2023-10-05" @default.
• W2170455802 title "Replication fork stalling and cell cycle arrest in UV-irradiated <i>Escherichia coli</i>" @default.
• W2170455802 cites W1498020501 @default.
• W2170455802 cites W1519780429 @default.
• W2170455802 cites W1854173852 @default.
• W2170455802 cites W1861951729 @default.
• W2170455802 cites W1866948286 @default.
• W2170455802 cites W1922809098 @default.
• W2170455802 cites W1964370576 @default.
• W2170455802 cites W1965780315 @default.
• W2170455802 cites W1972522403 @default.
• W2170455802 cites W1973721031 @default.
• W2170455802 cites W1980433374 @default.
• W2170455802 cites W1981228645 @default.
• W2170455802 cites W1982729145 @default.
• W2170455802 cites W1984459901 @default.
• W2170455802 cites W1987170498 @default.
• W2170455802 cites W1992036233 @default.
• W2170455802 cites W1995004577 @default.
• W2170455802 cites W2000826427 @default.
• W2170455802 cites W2014442287 @default.
• W2170455802 cites W2023596735 @default.
• W2170455802 cites W2032004743 @default.
• W2170455802 cites W2038238224 @default.
• W2170455802 cites W2039438812 @default.
• W2170455802 cites W2045806327 @default.
• W2170455802 cites W2048680704 @default.
• W2170455802 cites W2069103574 @default.
• W2170455802 cites W2069757035 @default.
• W2170455802 cites W2070910548 @default.
• W2170455802 cites W2079741709 @default.
• W2170455802 cites W2083123225 @default.
• W2170455802 cites W2083513756 @default.
• W2170455802 cites W2091098505 @default.
• W2170455802 cites W2096353190 @default.
• W2170455802 cites W2114809602 @default.
• W2170455802 cites W2134333587 @default.
• W2170455802 cites W2137227311 @default.
• W2170455802 cites W2140220147 @default.
• W2170455802 cites W1986887380 @default.
• W2170455802 doi "https://doi.org/10.1101/gad.417607" @default.
• W2170455802 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1820941" @default.
• W2170455802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17369400" @default.
• W2170455802 hasPublicationYear "2007" @default.
• W2170455802 type Work @default.
• W2170455802 sameAs 2170455802 @default.
• W2170455802 citedByCount "72" @default.
• W2170455802 countsByYear W21704558022012 @default.
• W2170455802 countsByYear W21704558022013 @default.
• W2170455802 countsByYear W21704558022014 @default.
• W2170455802 countsByYear W21704558022015 @default.
• W2170455802 countsByYear W21704558022016 @default.
• W2170455802 countsByYear W21704558022017 @default.
• W2170455802 countsByYear W21704558022018 @default.
• W2170455802 countsByYear W21704558022019 @default.
• W2170455802 countsByYear W21704558022020 @default.
• W2170455802 countsByYear W21704558022021 @default.
• W2170455802 countsByYear W21704558022022 @default.
• W2170455802 countsByYear W21704558022023 @default.
• W2170455802 crossrefType "journal-article" @default.
• W2170455802 hasAuthorship W2170455802A5000430518 @default.
• W2170455802 hasAuthorship W2170455802A5025661928 @default.
• W2170455802 hasAuthorship W2170455802A5033424893 @default.
• W2170455802 hasBestOaLocation W21704558021 @default.
• W2170455802 hasConcept C104317684 @default.
• W2170455802 hasConcept C104690221 @default.
• W2170455802 hasConcept C107827726 @default.
• W2170455802 hasConcept C116107829 @default.
• W2170455802 hasConcept C12590798 @default.
• W2170455802 hasConcept C159047783 @default.
• W2170455802 hasConcept C161223559 @default.
• W2170455802 hasConcept C41141232 @default.
• W2170455802 hasConcept C54355233 @default.
• W2170455802 hasConcept C552990157 @default.
• W2170455802 hasConcept C58337764 @default.
• W2170455802 hasConcept C64241487 @default.
• W2170455802 hasConcept C67705224 @default.
• W2170455802 hasConcept C73573662 @default.
• W2170455802 hasConcept C86803240 @default.
• W2170455802 hasConcept C95444343 @default.
• W2170455802 hasConceptScore W2170455802C104317684 @default.
• W2170455802 hasConceptScore W2170455802C104690221 @default.
• W2170455802 hasConceptScore W2170455802C107827726 @default.
• W2170455802 hasConceptScore W2170455802C116107829 @default.
• W2170455802 hasConceptScore W2170455802C12590798 @default.
• W2170455802 hasConceptScore W2170455802C159047783 @default.
• W2170455802 hasConceptScore W2170455802C161223559 @default.
• W2170455802 hasConceptScore W2170455802C41141232 @default.
• W2170455802 hasConceptScore W2170455802C54355233 @default.
• W2170455802 hasConceptScore W2170455802C552990157 @default.
• W2170455802 hasConceptScore W2170455802C58337764 @default.
• W2170455802 hasConceptScore W2170455802C64241487 @default.

• next