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• W2170558219 startingPage "1200" @default.
• W2170558219 abstract "It has recently been demonstrated that ribosomes are preferentially localized outside the nucleoid in Escherichia coli , but little is known about the spatial regulation of pre-rRNA processing. In this work, I investigate the cellular distribution of leader pre-rRNAs using RNA-FISH. In contrast to mature rRNA, the 5′ proximal leader region associates with the nucleoid, and this association occurs in an RNase III-dependent manner. Moreover, RNase III plays a role in the rapid induction of ribosomal operons during outgrowth and is essential in the absence of the transcriptional regulator Fis, suggesting a linkage of transcription and RNA processing for ribosomal operons in E. coli ." @default.
• W2170558219 created "2016-06-24" @default.
• W2170558219 creator A5042924184 @default.
• W2170558219 date "2013-07-26" @default.
• W2170558219 modified "2023-10-18" @default.
• W2170558219 title "RNase III is required for localization to the nucleoid of the 5′ pre-rRNA leader and for optimal induction of rRNA synthesis in <i>E. coli</i>" @default.
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• W2170558219 doi "https://doi.org/10.1261/rna.038588.113" @default.
• W2170558219 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3753927" @default.
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