FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170574059> ?p ?o ?g. }

• W2170574059 endingPage "1012" @default.
• W2170574059 startingPage "1007" @default.
• W2170574059 abstract "The aim of this study was to confirm if catabolism of all-trans retinoic acid (RA) is enhanced by type I cellular retinoic acid binding protein (CRABP-I) expression and to investigate the effect of this enhanced catabolism on cell proliferation of the head and neck squamous cell carcinoma (HNSCC) cell line, AMC-HN-7. We also analyzed the effects of CRABP-I on RA-induced retinoic acid receptor (RAR) activity. The expression of the CRABP-I in stably transfected AMC-HN-7 cell lines (HN7-BPIa and HN7-BPIb) resulted in a lower sensitivity to administered RA compared with that of controls in a clonogenic assay. HN7-BPIs cells showed an increased amount of polar metabolites of RA in thin-layer chromatography. The transcriptional activity of the reporter plasmid RARE(DR5)-tk-CAT after the treatment of RA was lesser in HN7-BPIs than in controls. These results suggest that the increased CYP26-mediated catabolism of RA by CRABP-I transfection might decrease the amount of RA that is accessible to the nuclear receptors and make HNSCC cells resistant to RA." @default.
• W2170574059 created "2016-06-24" @default.
• W2170574059 creator A5009612121 @default.
• W2170574059 creator A5029512205 @default.
• W2170574059 creator A5031678345 @default.
• W2170574059 creator A5032796168 @default.
• W2170574059 creator A5039594995 @default.
• W2170574059 creator A5063335685 @default.
• W2170574059 creator A5063672379 @default.
• W2170574059 creator A5076196426 @default.
• W2170574059 creator A5077920695 @default.
• W2170574059 date "2004-08-01" @default.
• W2170574059 modified "2023-10-15" @default.
• W2170574059 title "The effect of cellular retinoic acid binding protein-I expression on the CYP26-mediated catabolism of all-trans retinoic acid and cell proliferation in head and neck squamous cell carcinoma" @default.
• W2170574059 cites W1556248806 @default.
• W2170574059 cites W1570165358 @default.
• W2170574059 cites W1927684145 @default.
• W2170574059 cites W1977386090 @default.
• W2170574059 cites W1987784290 @default.
• W2170574059 cites W2001068122 @default.
• W2170574059 cites W2001503472 @default.
• W2170574059 cites W2014591899 @default.
• W2170574059 cites W2023652393 @default.
• W2170574059 cites W2042570612 @default.
• W2170574059 cites W2049158888 @default.
• W2170574059 cites W2103440968 @default.
• W2170574059 cites W2170641379 @default.
• W2170574059 cites W2171990522 @default.
• W2170574059 cites W4230170105 @default.
• W2170574059 doi "https://doi.org/10.1016/j.metabol.2003.12.015" @default.
• W2170574059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15281009" @default.
• W2170574059 hasPublicationYear "2004" @default.
• W2170574059 type Work @default.
• W2170574059 sameAs 2170574059 @default.
• W2170574059 citedByCount "34" @default.
• W2170574059 countsByYear W21705740592012 @default.
• W2170574059 countsByYear W21705740592013 @default.
• W2170574059 countsByYear W21705740592014 @default.
• W2170574059 countsByYear W21705740592015 @default.
• W2170574059 countsByYear W21705740592016 @default.
• W2170574059 countsByYear W21705740592017 @default.
• W2170574059 countsByYear W21705740592019 @default.
• W2170574059 countsByYear W21705740592020 @default.
• W2170574059 countsByYear W21705740592021 @default.
• W2170574059 countsByYear W21705740592022 @default.
• W2170574059 countsByYear W21705740592023 @default.
• W2170574059 crossrefType "journal-article" @default.
• W2170574059 hasAuthorship W2170574059A5009612121 @default.
• W2170574059 hasAuthorship W2170574059A5029512205 @default.
• W2170574059 hasAuthorship W2170574059A5031678345 @default.
• W2170574059 hasAuthorship W2170574059A5032796168 @default.
• W2170574059 hasAuthorship W2170574059A5039594995 @default.
• W2170574059 hasAuthorship W2170574059A5063335685 @default.
• W2170574059 hasAuthorship W2170574059A5063672379 @default.
• W2170574059 hasAuthorship W2170574059A5076196426 @default.
• W2170574059 hasAuthorship W2170574059A5077920695 @default.
• W2170574059 hasConcept C117262875 @default.
• W2170574059 hasConcept C120197328 @default.
• W2170574059 hasConcept C121608353 @default.
• W2170574059 hasConcept C126322002 @default.
• W2170574059 hasConcept C1491633281 @default.
• W2170574059 hasConcept C153911025 @default.
• W2170574059 hasConcept C185592680 @default.
• W2170574059 hasConcept C2776530083 @default.
• W2170574059 hasConcept C2776833033 @default.
• W2170574059 hasConcept C2779963572 @default.
• W2170574059 hasConcept C2781121885 @default.
• W2170574059 hasConcept C502942594 @default.
• W2170574059 hasConcept C54009773 @default.
• W2170574059 hasConcept C54355233 @default.
• W2170574059 hasConcept C55493867 @default.
• W2170574059 hasConcept C62112901 @default.
• W2170574059 hasConcept C62231903 @default.
• W2170574059 hasConcept C71924100 @default.
• W2170574059 hasConcept C81885089 @default.
• W2170574059 hasConcept C86803240 @default.
• W2170574059 hasConcept C96942376 @default.
• W2170574059 hasConceptScore W2170574059C117262875 @default.
• W2170574059 hasConceptScore W2170574059C120197328 @default.
• W2170574059 hasConceptScore W2170574059C121608353 @default.
• W2170574059 hasConceptScore W2170574059C126322002 @default.
• W2170574059 hasConceptScore W2170574059C1491633281 @default.
• W2170574059 hasConceptScore W2170574059C153911025 @default.
• W2170574059 hasConceptScore W2170574059C185592680 @default.
• W2170574059 hasConceptScore W2170574059C2776530083 @default.
• W2170574059 hasConceptScore W2170574059C2776833033 @default.
• W2170574059 hasConceptScore W2170574059C2779963572 @default.
• W2170574059 hasConceptScore W2170574059C2781121885 @default.
• W2170574059 hasConceptScore W2170574059C502942594 @default.
• W2170574059 hasConceptScore W2170574059C54009773 @default.
• W2170574059 hasConceptScore W2170574059C54355233 @default.
• W2170574059 hasConceptScore W2170574059C55493867 @default.
• W2170574059 hasConceptScore W2170574059C62112901 @default.
• W2170574059 hasConceptScore W2170574059C62231903 @default.
• W2170574059 hasConceptScore W2170574059C71924100 @default.
• W2170574059 hasConceptScore W2170574059C81885089 @default.
• W2170574059 hasConceptScore W2170574059C86803240 @default.
• W2170574059 hasConceptScore W2170574059C96942376 @default.

• next