Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170576230> ?p ?o ?g. }
- W2170576230 abstract "Polymerization of microtubules is ubiquitous in biological cells and under certain conditions it becomes oscillatory in time. Here, simple reaction models are analyzed that capture such oscillations as well as the length distribution of microtubules. We assume reaction conditions that are stationary over many oscillation periods, and it is a Hopf bifurcation that leads to a persistent oscillatory microtubule polymerization in these models. Analytical expressions are derived for the threshold of the bifurcation and the oscillation frequency in terms of reaction rates, and typical trends of their parameter dependence are presented. Both, a catastrophe rate that depends on the density of guanosine triphosphate liganded tubulin dimers and a delay reaction, such as the depolymerization of shrinking microtubules or the decay of oligomers, support oscillations. For a tubulin dimer concentration below the threshold, oscillatory microtubule polymerization occurs transiently on the route to a stationary state, as shown by numerical solutions of the model equations. Close to threshold, a so-called amplitude equation is derived and it is shown that the bifurcation to microtubule oscillations is supercritical." @default.
- W2170576230 created "2016-06-24" @default.
- W2170576230 creator A5010982022 @default.
- W2170576230 creator A5014992689 @default.
- W2170576230 date "2003-02-14" @default.
- W2170576230 modified "2023-09-26" @default.
- W2170576230 title "Modeling oscillatory microtubule polymerization" @default.
- W2170576230 cites W1493226881 @default.
- W2170576230 cites W1503265874 @default.
- W2170576230 cites W1539269718 @default.
- W2170576230 cites W1588013556 @default.
- W2170576230 cites W1651112926 @default.
- W2170576230 cites W176353245 @default.
- W2170576230 cites W1965404941 @default.
- W2170576230 cites W1967856627 @default.
- W2170576230 cites W1977014966 @default.
- W2170576230 cites W1981680566 @default.
- W2170576230 cites W1992322422 @default.
- W2170576230 cites W2002094651 @default.
- W2170576230 cites W2002652733 @default.
- W2170576230 cites W2010286179 @default.
- W2170576230 cites W2011024886 @default.
- W2170576230 cites W2013862371 @default.
- W2170576230 cites W2018650334 @default.
- W2170576230 cites W2029189987 @default.
- W2170576230 cites W2035683801 @default.
- W2170576230 cites W2038307970 @default.
- W2170576230 cites W2041809821 @default.
- W2170576230 cites W2042351695 @default.
- W2170576230 cites W2056172042 @default.
- W2170576230 cites W2066243413 @default.
- W2170576230 cites W2086126894 @default.
- W2170576230 cites W2093052013 @default.
- W2170576230 cites W2095297646 @default.
- W2170576230 cites W2095579053 @default.
- W2170576230 cites W2096292802 @default.
- W2170576230 cites W2097151388 @default.
- W2170576230 cites W2101740285 @default.
- W2170576230 cites W2157319245 @default.
- W2170576230 cites W2180732247 @default.
- W2170576230 cites W2217436665 @default.
- W2170576230 cites W2417531034 @default.
- W2170576230 cites W3191847295 @default.
- W2170576230 cites W4213094588 @default.
- W2170576230 cites W4243904728 @default.
- W2170576230 cites W4248131049 @default.
- W2170576230 cites W2471097671 @default.
- W2170576230 doi "https://doi.org/10.1103/physreve.67.021903" @default.
- W2170576230 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12636711" @default.
- W2170576230 hasPublicationYear "2003" @default.
- W2170576230 type Work @default.
- W2170576230 sameAs 2170576230 @default.
- W2170576230 citedByCount "24" @default.
- W2170576230 countsByYear W21705762302012 @default.
- W2170576230 countsByYear W21705762302015 @default.
- W2170576230 countsByYear W21705762302016 @default.
- W2170576230 countsByYear W21705762302018 @default.
- W2170576230 countsByYear W21705762302022 @default.
- W2170576230 crossrefType "journal-article" @default.
- W2170576230 hasAuthorship W2170576230A5010982022 @default.
- W2170576230 hasAuthorship W2170576230A5014992689 @default.
- W2170576230 hasBestOaLocation W21705762302 @default.
- W2170576230 hasConcept C10447061 @default.
- W2170576230 hasConcept C121332964 @default.
- W2170576230 hasConcept C1491633281 @default.
- W2170576230 hasConcept C158622935 @default.
- W2170576230 hasConcept C159467904 @default.
- W2170576230 hasConcept C172435161 @default.
- W2170576230 hasConcept C185592680 @default.
- W2170576230 hasConcept C188027245 @default.
- W2170576230 hasConcept C20418707 @default.
- W2170576230 hasConcept C2778439541 @default.
- W2170576230 hasConcept C2779546866 @default.
- W2170576230 hasConcept C2781349735 @default.
- W2170576230 hasConcept C2909009945 @default.
- W2170576230 hasConcept C29537977 @default.
- W2170576230 hasConcept C41999313 @default.
- W2170576230 hasConcept C44228677 @default.
- W2170576230 hasConcept C46141821 @default.
- W2170576230 hasConcept C49852136 @default.
- W2170576230 hasConcept C521977710 @default.
- W2170576230 hasConcept C55493867 @default.
- W2170576230 hasConcept C62520636 @default.
- W2170576230 hasConcept C84425145 @default.
- W2170576230 hasConcept C86803240 @default.
- W2170576230 hasConcept C94921385 @default.
- W2170576230 hasConcept C95444343 @default.
- W2170576230 hasConceptScore W2170576230C10447061 @default.
- W2170576230 hasConceptScore W2170576230C121332964 @default.
- W2170576230 hasConceptScore W2170576230C1491633281 @default.
- W2170576230 hasConceptScore W2170576230C158622935 @default.
- W2170576230 hasConceptScore W2170576230C159467904 @default.
- W2170576230 hasConceptScore W2170576230C172435161 @default.
- W2170576230 hasConceptScore W2170576230C185592680 @default.
- W2170576230 hasConceptScore W2170576230C188027245 @default.
- W2170576230 hasConceptScore W2170576230C20418707 @default.
- W2170576230 hasConceptScore W2170576230C2778439541 @default.
- W2170576230 hasConceptScore W2170576230C2779546866 @default.
- W2170576230 hasConceptScore W2170576230C2781349735 @default.
- W2170576230 hasConceptScore W2170576230C2909009945 @default.