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• W2170608930 abstract "Published dosing guidelines for treatment of Seasonal Affective Disorder (SAD) refer to photopic lux, which is not appropriate for short-wavelength light. Short wavelengths are most potent for many non-visual responses to light. If SAD therapy were similarly mediated, standards utilizing lux risk overestimating necessary dose. We investigated antidepressant responses to light using two light-emitting diode (LED) sources, each emitting substantial short-wavelength light, but <2500 lux.A randomized, double-blind trial investigated 3-week 45 min/day out-patient treatment with blue-appearing (goLITE) or blue-enriched white-appearing light in 18 moderately-depressed adults (12F, 49.1 +/- 9.5 years). Equivalent numbers of photons within the short-wavelength range were emitted, but the white source emitted twice as many photons overall and seven-fold more lux.Depression ratings (SIGH-ADS; http://www.cet.org) decrease averaged 82% (SD = 17%) from baseline (P < 0.0001) in both white- and blue-light groups. Both sources were well tolerated.Short-wavelength LED light sources may be effective in SAD treatment at fewer lux than traditional fluorescent sources." @default.
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• W2170608930 date "2009-09-01" @default.
• W2170608930 modified "2023-10-14" @default.
• W2170608930 title "Lux vs. wavelength in light treatment of Seasonal Affective Disorder" @default.
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• W2170608930 doi "https://doi.org/10.1111/j.1600-0447.2009.01345.x" @default.
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