Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170610860> ?p ?o ?g. }
- W2170610860 abstract "The change of classical drug discovery to high-throughput screening (HTS) of large new combinatorial libraries and existing compound collections have led to an increased pressure of more rapid ADME (absorption, distribution, metabolism, elimination) evaluation (Smith and van de Waterbeemd 1999; Bertrand et al. 2000; Watt et al. 2000). Furthermore, various analyses of historical attrition data have revealed that pharmacokinetic (PK) problems, including poor absorption, low bioavailability and issues around drug-drug interactions, are important causes of attrition and should be addressed early in the discovery process. In recent years pharmaceutical companies have, therefore, increasingly put an effort in developing high-throughput screens for physicochemical and biopharmaceutical properties, as well as various ADME properties." @default.
- W2170610860 created "2016-06-24" @default.
- W2170610860 creator A5074868557 @default.
- W2170610860 date "2002-01-01" @default.
- W2170610860 modified "2023-09-26" @default.
- W2170610860 title "Relation of Molecular Properties with Drug Absorption and Disposition" @default.
- W2170610860 cites W1479740310 @default.
- W2170610860 cites W1492954502 @default.
- W2170610860 cites W1494838316 @default.
- W2170610860 cites W1502481848 @default.
- W2170610860 cites W1510224559 @default.
- W2170610860 cites W1545231783 @default.
- W2170610860 cites W1574994167 @default.
- W2170610860 cites W1604459930 @default.
- W2170610860 cites W185703129 @default.
- W2170610860 cites W1965170261 @default.
- W2170610860 cites W1970202530 @default.
- W2170610860 cites W1976557020 @default.
- W2170610860 cites W1984860801 @default.
- W2170610860 cites W1988601069 @default.
- W2170610860 cites W1989451208 @default.
- W2170610860 cites W1991443437 @default.
- W2170610860 cites W2009335994 @default.
- W2170610860 cites W2009899562 @default.
- W2170610860 cites W2010552566 @default.
- W2170610860 cites W2010595835 @default.
- W2170610860 cites W2011505858 @default.
- W2170610860 cites W2016568950 @default.
- W2170610860 cites W2023344184 @default.
- W2170610860 cites W2026398446 @default.
- W2170610860 cites W2032794920 @default.
- W2170610860 cites W2035830147 @default.
- W2170610860 cites W2035997721 @default.
- W2170610860 cites W2043432919 @default.
- W2170610860 cites W2052859366 @default.
- W2170610860 cites W2053459380 @default.
- W2170610860 cites W2055726315 @default.
- W2170610860 cites W2058557855 @default.
- W2170610860 cites W2060365395 @default.
- W2170610860 cites W2061266768 @default.
- W2170610860 cites W2073808672 @default.
- W2170610860 cites W2083646919 @default.
- W2170610860 cites W2084466443 @default.
- W2170610860 cites W2092118786 @default.
- W2170610860 cites W2105077123 @default.
- W2170610860 cites W2144135270 @default.
- W2170610860 cites W2151681059 @default.
- W2170610860 cites W2166465687 @default.
- W2170610860 cites W2767707571 @default.
- W2170610860 cites W4236998267 @default.
- W2170610860 cites W4248107770 @default.
- W2170610860 doi "https://doi.org/10.1007/978-3-662-04383-7_11" @default.
- W2170610860 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11975197" @default.
- W2170610860 hasPublicationYear "2002" @default.
- W2170610860 type Work @default.
- W2170610860 sameAs 2170610860 @default.
- W2170610860 citedByCount "0" @default.
- W2170610860 crossrefType "book-chapter" @default.
- W2170610860 hasAuthorship W2170610860A5074868557 @default.
- W2170610860 hasConcept C110121322 @default.
- W2170610860 hasConcept C112705442 @default.
- W2170610860 hasConcept C125287762 @default.
- W2170610860 hasConcept C127413603 @default.
- W2170610860 hasConcept C134306372 @default.
- W2170610860 hasConcept C150903083 @default.
- W2170610860 hasConcept C15744967 @default.
- W2170610860 hasConcept C159985019 @default.
- W2170610860 hasConcept C181389837 @default.
- W2170610860 hasConcept C183696295 @default.
- W2170610860 hasConcept C185592680 @default.
- W2170610860 hasConcept C192562407 @default.
- W2170610860 hasConcept C2780035454 @default.
- W2170610860 hasConcept C2781047461 @default.
- W2170610860 hasConcept C33923547 @default.
- W2170610860 hasConcept C38022665 @default.
- W2170610860 hasConcept C41008148 @default.
- W2170610860 hasConcept C55493867 @default.
- W2170610860 hasConcept C69366308 @default.
- W2170610860 hasConcept C70721500 @default.
- W2170610860 hasConcept C71924100 @default.
- W2170610860 hasConcept C74187038 @default.
- W2170610860 hasConcept C77805123 @default.
- W2170610860 hasConcept C86803240 @default.
- W2170610860 hasConcept C98274493 @default.
- W2170610860 hasConceptScore W2170610860C110121322 @default.
- W2170610860 hasConceptScore W2170610860C112705442 @default.
- W2170610860 hasConceptScore W2170610860C125287762 @default.
- W2170610860 hasConceptScore W2170610860C127413603 @default.
- W2170610860 hasConceptScore W2170610860C134306372 @default.
- W2170610860 hasConceptScore W2170610860C150903083 @default.
- W2170610860 hasConceptScore W2170610860C15744967 @default.
- W2170610860 hasConceptScore W2170610860C159985019 @default.
- W2170610860 hasConceptScore W2170610860C181389837 @default.
- W2170610860 hasConceptScore W2170610860C183696295 @default.
- W2170610860 hasConceptScore W2170610860C185592680 @default.
- W2170610860 hasConceptScore W2170610860C192562407 @default.
- W2170610860 hasConceptScore W2170610860C2780035454 @default.
- W2170610860 hasConceptScore W2170610860C2781047461 @default.
- W2170610860 hasConceptScore W2170610860C33923547 @default.
- W2170610860 hasConceptScore W2170610860C38022665 @default.