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• W2170632475 abstract "Intracellular products such as recombinant insulin, which are typically produced in microbial host cells, demand a product release step to remove them from the cell. How this is performed determines the quantity of released contaminants, the particle size distribution of cell debris and the physical properties of the resultant process stream, which all impact on the performance of the downstream operations. Thus, achieving selective release of the desired product is crucial for improving the process economics. Advances in upstream processing (the bioreactor phase) have been successful in achieving high product titres, and downstream costs now typically dominate the overall manufacturing costs. Here, we review and discuss the selective release of products as a possible means of improving the efficiency of downstream processing. Intracellular products such as recombinant insulin, which are typically produced in microbial host cells, demand a product release step to remove them from the cell. How this is performed determines the quantity of released contaminants, the particle size distribution of cell debris and the physical properties of the resultant process stream, which all impact on the performance of the downstream operations. Thus, achieving selective release of the desired product is crucial for improving the process economics. Advances in upstream processing (the bioreactor phase) have been successful in achieving high product titres, and downstream costs now typically dominate the overall manufacturing costs. Here, we review and discuss the selective release of products as a possible means of improving the efficiency of downstream processing." @default.
• W2170632475 created "2016-06-24" @default.
• W2170632475 creator A5030852439 @default.
• W2170632475 creator A5054772413 @default.
• W2170632475 creator A5069874071 @default.
• W2170632475 date "2009-08-01" @default.
• W2170632475 modified "2023-10-10" @default.
• W2170632475 title "Advances in product release strategies and impact on bioprocess design" @default.
• W2170632475 cites W1508509739 @default.
• W2170632475 cites W1977992559 @default.
• W2170632475 cites W1980586640 @default.
• W2170632475 cites W1984403358 @default.
• W2170632475 cites W1986753849 @default.
• W2170632475 cites W1987786294 @default.
• W2170632475 cites W1987881951 @default.
• W2170632475 cites W1987920176 @default.
• W2170632475 cites W1990408119 @default.
• W2170632475 cites W1993028432 @default.
• W2170632475 cites W1994325260 @default.
• W2170632475 cites W1996201307 @default.
• W2170632475 cites W1998159443 @default.
• W2170632475 cites W2002266516 @default.
• W2170632475 cites W2005775932 @default.
• W2170632475 cites W2013510532 @default.
• W2170632475 cites W2017366960 @default.
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• W2170632475 cites W2019552004 @default.
• W2170632475 cites W2020244187 @default.
• W2170632475 cites W2020659596 @default.
• W2170632475 cites W2022814920 @default.
• W2170632475 cites W2023876635 @default.
• W2170632475 cites W2025381648 @default.
• W2170632475 cites W2026868764 @default.
• W2170632475 cites W2028494302 @default.
• W2170632475 cites W2034047360 @default.
• W2170632475 cites W2034773335 @default.
• W2170632475 cites W2036760528 @default.
• W2170632475 cites W2036770346 @default.
• W2170632475 cites W2044825931 @default.
• W2170632475 cites W2045122524 @default.
• W2170632475 cites W2046396005 @default.
• W2170632475 cites W2056368762 @default.
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• W2170632475 cites W2070314858 @default.
• W2170632475 cites W2070705474 @default.
• W2170632475 cites W2072482190 @default.
• W2170632475 cites W2076195477 @default.
• W2170632475 cites W2077616367 @default.
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• W2170632475 doi "https://doi.org/10.1016/j.tibtech.2009.04.004" @default.
• W2170632475 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19573944" @default.
• W2170632475 hasPublicationYear "2009" @default.
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