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- W2170682754 startingPage "481" @default.
- W2170682754 abstract "It has been over 25 years since the discovery of human T-cell leukemia virus type 1 (HTLV-1); however, the exact sequence of events that occur during primary infection, clinical latency or the development of disease remains unresolved. The advances in molecular virology and neuroimmunology have contributed significantly to our understanding of HTLV-1 pathogenesis, but also uncovered the complexity of the virus–host interaction both in the peripheral blood and the CNS. Here, we overview the general pathologic features of HTLV-1, molecular mechanisms of oncogenic transformation and characteristics of the host immune response during the associated neuroinflammatory process. We also discuss both current and new approaches in the diagnosis and therapy of HTLV-1 associated diseases – adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis. Finally, potentially important emerging areas of research that may have an impact on our understanding of the pathogenic mechanism have been briefly introduced." @default.
- W2170682754 created "2016-06-24" @default.
- W2170682754 creator A5004477312 @default.
- W2170682754 creator A5028053542 @default.
- W2170682754 creator A5034657105 @default.
- W2170682754 creator A5036704187 @default.
- W2170682754 date "2007-09-01" @default.
- W2170682754 modified "2023-10-17" @default.
- W2170682754 title "New insights into the pathogenesis, diagnosis and treatment of human T-cell leukemia virus type 1-induced disease" @default.
- W2170682754 cites W113187801 @default.
- W2170682754 cites W1495227372 @default.
- W2170682754 cites W1517745501 @default.
- W2170682754 cites W1535148395 @default.
- W2170682754 cites W1536745120 @default.
- W2170682754 cites W1538391963 @default.
- W2170682754 cites W1573101036 @default.
- W2170682754 cites W1593631074 @default.
- W2170682754 cites W1602002939 @default.
- W2170682754 cites W1789872954 @default.
- W2170682754 cites W1924919597 @default.
- W2170682754 cites W1966343819 @default.
- W2170682754 cites W1971982144 @default.
- W2170682754 cites W1973852185 @default.
- W2170682754 cites W1977581620 @default.
- W2170682754 cites W1979661087 @default.
- W2170682754 cites W1981433912 @default.
- W2170682754 cites W1983135251 @default.
- W2170682754 cites W1984615218 @default.
- W2170682754 cites W1986600046 @default.
- W2170682754 cites W1990080035 @default.
- W2170682754 cites W1990993204 @default.
- W2170682754 cites W1991941671 @default.
- W2170682754 cites W1994228428 @default.
- W2170682754 cites W1994602933 @default.
- W2170682754 cites W1997498480 @default.
- W2170682754 cites W2001612860 @default.
- W2170682754 cites W2004640739 @default.
- W2170682754 cites W2004827589 @default.
- W2170682754 cites W2009621572 @default.
- W2170682754 cites W2011173604 @default.
- W2170682754 cites W2012182694 @default.
- W2170682754 cites W2014765142 @default.
- W2170682754 cites W2016031883 @default.
- W2170682754 cites W2019574058 @default.
- W2170682754 cites W2019678711 @default.
- W2170682754 cites W2020146098 @default.
- W2170682754 cites W2020611114 @default.
- W2170682754 cites W2021057394 @default.
- W2170682754 cites W2023420238 @default.
- W2170682754 cites W2023615197 @default.
- W2170682754 cites W2024699155 @default.
- W2170682754 cites W2024803879 @default.
- W2170682754 cites W2025392129 @default.
- W2170682754 cites W2027209056 @default.
- W2170682754 cites W2030010089 @default.
- W2170682754 cites W2032184249 @default.
- W2170682754 cites W2035371681 @default.
- W2170682754 cites W2042125491 @default.
- W2170682754 cites W2042687143 @default.
- W2170682754 cites W2043616119 @default.
- W2170682754 cites W2046975789 @default.
- W2170682754 cites W2048193255 @default.
- W2170682754 cites W2050212070 @default.
- W2170682754 cites W2052452866 @default.
- W2170682754 cites W2062259331 @default.
- W2170682754 cites W2063287019 @default.
- W2170682754 cites W2065972249 @default.
- W2170682754 cites W2065973413 @default.
- W2170682754 cites W2070063277 @default.
- W2170682754 cites W2070677647 @default.
- W2170682754 cites W2071592765 @default.
- W2170682754 cites W2071794490 @default.
- W2170682754 cites W2072802635 @default.
- W2170682754 cites W2075715912 @default.
- W2170682754 cites W2077363016 @default.
- W2170682754 cites W2078089821 @default.
- W2170682754 cites W2079683432 @default.
- W2170682754 cites W2079929369 @default.
- W2170682754 cites W2080441045 @default.
- W2170682754 cites W2083891382 @default.
- W2170682754 cites W2083973629 @default.
- W2170682754 cites W2084714153 @default.
- W2170682754 cites W2085122076 @default.
- W2170682754 cites W2085715689 @default.
- W2170682754 cites W2086057674 @default.
- W2170682754 cites W2086143621 @default.
- W2170682754 cites W2088002901 @default.
- W2170682754 cites W2088362013 @default.
- W2170682754 cites W2089337693 @default.
- W2170682754 cites W2090462024 @default.
- W2170682754 cites W2091370762 @default.
- W2170682754 cites W2091374070 @default.
- W2170682754 cites W2091994700 @default.
- W2170682754 cites W2093350079 @default.
- W2170682754 cites W2093719891 @default.
- W2170682754 cites W2094343556 @default.
- W2170682754 cites W2094473104 @default.
- W2170682754 cites W2094831592 @default.