FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170682771> ?p ?o ?g. }

• W2170682771 endingPage "32" @default.
• W2170682771 startingPage "124" @default.
• W2170682771 abstract "Analysis of the microdeletions in the azoospermia factor (AZF) region of Y chromosome by PCR is an important screening tool in the work-up of infertile males opting for assisted reproductive techniques. In the present study, the Y chromosome microdeletions were analyzed by PCR using primers corresponding to 16 sequence tagged sites (STS) and three genes of the AZF region in infertile Indian men. Feasibility of developing a simplified multiplex PCR for screening of the Y chromosome microdeletions has been explored.A total of 271 male subjects were analyzed, of which, 170 were infertile patients (51 oligospermic and 119 azoospermic) and 101 were fertile controls. Subjects showing normal karyotype only were included in the study. The semen analysis was done and plasma follicle stimulating hormone (FSH) concentrations were determined by radioimmunoassay. Testicular histopathology was analyzed by fine needle aspiration cytology (FNAC).Y chromosome microdeletions were observed in nine out of 170 (5.29%) infertile males all of whom were azoospermic. Of the nine subjects, two had deletions in AZFa, one in AZFb, three in AZFc and three in AZFb+c regions. No deletions were observed in the infertile severe oligospermic men (< 5 million sperm/ml semen) and fertile controls. No difference in the FSH concentrations of infertile patients with and without deletions (18.36 and 18.10 mIU/ml respectively) was observed. A clear relationship between Y chromosome microdeletions and testicular phenotypes could not be established. Two multiplex PCRs were designed using 7 STSs markers, which could detect Y chromosome microdeletions in infertile male subjects as efficiently as PCR based on larger number of PCR reactions.The multiplex PCRs described in the present study may be a suitable, cost-effective and less time consuming method for screening the Y chromosome deletions in infertile males in routine clinical diagnosis and counselling prior to assisted reproduction." @default.
• W2170682771 created "2016-06-24" @default.
• W2170682771 creator A5019169610 @default.
• W2170682771 creator A5020677450 @default.
• W2170682771 creator A5028303144 @default.
• W2170682771 creator A5030297371 @default.
• W2170682771 creator A5038368157 @default.
• W2170682771 creator A5073399728 @default.
• W2170682771 date "2008-02-01" @default.
• W2170682771 modified "2023-09-29" @default.
• W2170682771 title "Screening for Y-chromosome microdeletions in infertile Indian males: utility of simplified multiplex PCR." @default.
• W2170682771 cites W1586722421 @default.
• W2170682771 cites W1985334950 @default.
• W2170682771 cites W1994153956 @default.
• W2170682771 cites W2001276114 @default.
• W2170682771 cites W2007233513 @default.
• W2170682771 cites W2017961219 @default.
• W2170682771 cites W2035506380 @default.
• W2170682771 cites W2039259879 @default.
• W2170682771 cites W2047803717 @default.
• W2170682771 cites W2050568852 @default.
• W2170682771 cites W2055475516 @default.
• W2170682771 cites W2059018121 @default.
• W2170682771 cites W2078096350 @default.
• W2170682771 cites W2082233801 @default.
• W2170682771 cites W2085331328 @default.
• W2170682771 cites W2098236973 @default.
• W2170682771 cites W2107478853 @default.
• W2170682771 cites W2111486924 @default.
• W2170682771 cites W2118487279 @default.
• W2170682771 cites W2123581103 @default.
• W2170682771 cites W2130991360 @default.
• W2170682771 cites W2138174091 @default.
• W2170682771 cites W2138617055 @default.
• W2170682771 cites W2148836413 @default.
• W2170682771 cites W2151785652 @default.
• W2170682771 cites W2159163928 @default.
• W2170682771 cites W2161414825 @default.
• W2170682771 cites W2163849750 @default.
• W2170682771 cites W2166576186 @default.
• W2170682771 cites W2171792506 @default.
• W2170682771 cites W2320043328 @default.
• W2170682771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18403789" @default.
• W2170682771 hasPublicationYear "2008" @default.
• W2170682771 type Work @default.
• W2170682771 sameAs 2170682771 @default.
• W2170682771 citedByCount "16" @default.
• W2170682771 countsByYear W21706827712012 @default.
• W2170682771 countsByYear W21706827712013 @default.
• W2170682771 countsByYear W21706827712014 @default.
• W2170682771 countsByYear W21706827712015 @default.
• W2170682771 countsByYear W21706827712017 @default.
• W2170682771 countsByYear W21706827712018 @default.
• W2170682771 crossrefType "journal-article" @default.
• W2170682771 hasAuthorship W2170682771A5019169610 @default.
• W2170682771 hasAuthorship W2170682771A5020677450 @default.
• W2170682771 hasAuthorship W2170682771A5028303144 @default.
• W2170682771 hasAuthorship W2170682771A5030297371 @default.
• W2170682771 hasAuthorship W2170682771A5038368157 @default.
• W2170682771 hasAuthorship W2170682771A5073399728 @default.
• W2170682771 hasConcept C104317684 @default.
• W2170682771 hasConcept C16685009 @default.
• W2170682771 hasConcept C2776029846 @default.
• W2170682771 hasConcept C2777338322 @default.
• W2170682771 hasConcept C2777420699 @default.
• W2170682771 hasConcept C2777589648 @default.
• W2170682771 hasConcept C2777688143 @default.
• W2170682771 hasConcept C2778093475 @default.
• W2170682771 hasConcept C2779234561 @default.
• W2170682771 hasConcept C2780246931 @default.
• W2170682771 hasConcept C2780424099 @default.
• W2170682771 hasConcept C29456083 @default.
• W2170682771 hasConcept C30481170 @default.
• W2170682771 hasConcept C53226629 @default.
• W2170682771 hasConcept C54355233 @default.
• W2170682771 hasConcept C71924100 @default.
• W2170682771 hasConcept C86803240 @default.
• W2170682771 hasConceptScore W2170682771C104317684 @default.
• W2170682771 hasConceptScore W2170682771C16685009 @default.
• W2170682771 hasConceptScore W2170682771C2776029846 @default.
• W2170682771 hasConceptScore W2170682771C2777338322 @default.
• W2170682771 hasConceptScore W2170682771C2777420699 @default.
• W2170682771 hasConceptScore W2170682771C2777589648 @default.
• W2170682771 hasConceptScore W2170682771C2777688143 @default.
• W2170682771 hasConceptScore W2170682771C2778093475 @default.
• W2170682771 hasConceptScore W2170682771C2779234561 @default.
• W2170682771 hasConceptScore W2170682771C2780246931 @default.
• W2170682771 hasConceptScore W2170682771C2780424099 @default.
• W2170682771 hasConceptScore W2170682771C29456083 @default.
• W2170682771 hasConceptScore W2170682771C30481170 @default.
• W2170682771 hasConceptScore W2170682771C53226629 @default.
• W2170682771 hasConceptScore W2170682771C54355233 @default.
• W2170682771 hasConceptScore W2170682771C71924100 @default.
• W2170682771 hasConceptScore W2170682771C86803240 @default.
• W2170682771 hasIssue "2" @default.
• W2170682771 hasLocation W21706827711 @default.
• W2170682771 hasOpenAccess W2170682771 @default.
• W2170682771 hasPrimaryLocation W21706827711 @default.

• next