Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170708300> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2170708300 endingPage "550" @default.
- W2170708300 startingPage "545" @default.
- W2170708300 abstract "The United States Public Health Service Substance Abuse and Mental Health Services Administration is alerting medical professionals that a substantial percentage of cocaine imported into the United States is adulterated with levamisole, a veterinary pharmaceutical that can cause blood cell disorders such as severe neutropenia and agranulocytosis. Levamisole HCl is the active ingredient in a number of veterinary drugs approved to treat worm infestations in animals. Levamisole HCl was also the active ingredient in a human drug for oral administration approved on June 18, 1990, as adjuvant treatment in combination with fluorouracil after surgical resection in patients with Duke's stage C colon cancer. This drug was withdrawn from the U.S. market around 2000, and it has not been marketed in the U.S. since then. The objective of this study was to develop a method to determine the amount of levamisole in urine samples. The procedure will be provided to state health laboratories as needed to be used in the evaluation of patients that have developed neutropenia or agranulocytosis in the setting of recent cocaine use. A gas chromatography-mass spectrometry method was validated and tested at two different laboratories, and the method limit of detection for levamisole is 1 ng/mL in urine when using a 5-mL sample. Confirmation of the stereoisomer of levamisole was done by high-performance liquid chromatography using a chiral column." @default.
- W2170708300 created "2016-06-24" @default.
- W2170708300 creator A5030658221 @default.
- W2170708300 creator A5032178874 @default.
- W2170708300 creator A5033031679 @default.
- W2170708300 creator A5056909195 @default.
- W2170708300 creator A5066559923 @default.
- W2170708300 creator A5072522740 @default.
- W2170708300 creator A5076360659 @default.
- W2170708300 creator A5079900296 @default.
- W2170708300 creator A5085137338 @default.
- W2170708300 date "2011-10-01" @default.
- W2170708300 modified "2023-10-07" @default.
- W2170708300 title "Determination of Levamisole in Urine by Gas Chromatography-Mass Spectrometry" @default.
- W2170708300 cites W1538332718 @default.
- W2170708300 cites W1965457377 @default.
- W2170708300 cites W1989123522 @default.
- W2170708300 cites W1994578196 @default.
- W2170708300 cites W2009356872 @default.
- W2170708300 cites W2016347068 @default.
- W2170708300 cites W2025224980 @default.
- W2170708300 cites W2037513745 @default.
- W2170708300 cites W2048112488 @default.
- W2170708300 cites W2146837339 @default.
- W2170708300 cites W2187991326 @default.
- W2170708300 doi "https://doi.org/10.1093/anatox/35.8.545" @default.
- W2170708300 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22004673" @default.
- W2170708300 hasPublicationYear "2011" @default.
- W2170708300 type Work @default.
- W2170708300 sameAs 2170708300 @default.
- W2170708300 citedByCount "15" @default.
- W2170708300 countsByYear W21707083002012 @default.
- W2170708300 countsByYear W21707083002013 @default.
- W2170708300 countsByYear W21707083002014 @default.
- W2170708300 countsByYear W21707083002016 @default.
- W2170708300 countsByYear W21707083002017 @default.
- W2170708300 countsByYear W21707083002018 @default.
- W2170708300 countsByYear W21707083002019 @default.
- W2170708300 countsByYear W21707083002021 @default.
- W2170708300 countsByYear W21707083002023 @default.
- W2170708300 crossrefType "journal-article" @default.
- W2170708300 hasAuthorship W2170708300A5030658221 @default.
- W2170708300 hasAuthorship W2170708300A5032178874 @default.
- W2170708300 hasAuthorship W2170708300A5033031679 @default.
- W2170708300 hasAuthorship W2170708300A5056909195 @default.
- W2170708300 hasAuthorship W2170708300A5066559923 @default.
- W2170708300 hasAuthorship W2170708300A5072522740 @default.
- W2170708300 hasAuthorship W2170708300A5076360659 @default.
- W2170708300 hasAuthorship W2170708300A5079900296 @default.
- W2170708300 hasAuthorship W2170708300A5085137338 @default.
- W2170708300 hasConcept C126322002 @default.
- W2170708300 hasConcept C160735492 @default.
- W2170708300 hasConcept C162324750 @default.
- W2170708300 hasConcept C185592680 @default.
- W2170708300 hasConcept C2780026642 @default.
- W2170708300 hasConcept C2781325985 @default.
- W2170708300 hasConcept C3019806175 @default.
- W2170708300 hasConcept C43617362 @default.
- W2170708300 hasConcept C50522688 @default.
- W2170708300 hasConcept C71924100 @default.
- W2170708300 hasConceptScore W2170708300C126322002 @default.
- W2170708300 hasConceptScore W2170708300C160735492 @default.
- W2170708300 hasConceptScore W2170708300C162324750 @default.
- W2170708300 hasConceptScore W2170708300C185592680 @default.
- W2170708300 hasConceptScore W2170708300C2780026642 @default.
- W2170708300 hasConceptScore W2170708300C2781325985 @default.
- W2170708300 hasConceptScore W2170708300C3019806175 @default.
- W2170708300 hasConceptScore W2170708300C43617362 @default.
- W2170708300 hasConceptScore W2170708300C50522688 @default.
- W2170708300 hasConceptScore W2170708300C71924100 @default.
- W2170708300 hasIssue "8" @default.
- W2170708300 hasLocation W21707083001 @default.
- W2170708300 hasLocation W21707083002 @default.
- W2170708300 hasOpenAccess W2170708300 @default.
- W2170708300 hasPrimaryLocation W21707083001 @default.
- W2170708300 hasRelatedWork W1506200166 @default.
- W2170708300 hasRelatedWork W1995515455 @default.
- W2170708300 hasRelatedWork W2080531066 @default.
- W2170708300 hasRelatedWork W2234071437 @default.
- W2170708300 hasRelatedWork W2480902373 @default.
- W2170708300 hasRelatedWork W2748952813 @default.
- W2170708300 hasRelatedWork W2899084033 @default.
- W2170708300 hasRelatedWork W3031052312 @default.
- W2170708300 hasRelatedWork W3032375762 @default.
- W2170708300 hasRelatedWork W3108674512 @default.
- W2170708300 hasVolume "35" @default.
- W2170708300 isParatext "false" @default.
- W2170708300 isRetracted "false" @default.
- W2170708300 magId "2170708300" @default.
- W2170708300 workType "article" @default.