Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170741749> ?p ?o ?g. }
- W2170741749 endingPage "922" @default.
- W2170741749 startingPage "914" @default.
- W2170741749 abstract "BACKGROUND: Renal insufficiency adversely affects outcomes after cardiac and vascular surgery. The effect of preoperative renal insufficiency on outcomes after major hepatectomy is unknown. STUDY DESIGN: All patients who underwent major hepatectomy (≥3 segments) at 3 institutions from 2000 to 2012 were identified. Resections were performed using low central venous pressure anesthesia. Renal function was analyzed by preoperative serum creatinine (sCr) level. Primary outcomes were major complications (Clavien grade III to V), respiratory failure, renal failure requiring hemodialysis, and 90-day mortality. RESULTS: One thousand one hundred and seventy patients had preoperative sCr levels available. Renal function was analyzed using sCr dichotomized at 1.8 mg/dL, 1 SD higher than the mean value (0.97 ± 0.79 mg/dL) for the cohort. Twenty-two patients had sCr ≥1.8 mg/dL. Major complications occurred in 279 patients (23.8%), respiratory failure in 62 (5.3%), and renal failure in 31 (2.6%). Ninety-day mortality rate was 5.4%. On multivariate analysis, patients with sCr ≥1.8 mg/dL remained at significantly increased risk for major complications (hazard ratio = 3.94; 95% CI, 1.48–10.49; p = 0.006), respiratory failure (hazard ratio = 4.43; 95% CI, 1.33–14.80; p = 0.014), and renal failure (hazard ratio = 4.75; 95% CI, 1.19–18.97; p = 0.028). Serum Cr ≥1.8 mg/dL was not independently associated with 90-day mortality on multivariate analysis (p = 0.27). CONCLUSIONS: Preoperative serum creatinine ≥1.8 mg/dL identifies patients at significantly increased risk of postoperative major complications, respiratory failure, and renal failure requiring dialysis. Patients are well selected for major hepatectomy, and few patients with substantial renal insufficiency are deemed operative candidates." @default.
- W2170741749 created "2016-06-24" @default.
- W2170741749 creator A5002780450 @default.
- W2170741749 creator A5014218695 @default.
- W2170741749 creator A5025524746 @default.
- W2170741749 creator A5026053250 @default.
- W2170741749 creator A5027872333 @default.
- W2170741749 creator A5029089899 @default.
- W2170741749 creator A5036799246 @default.
- W2170741749 creator A5047326383 @default.
- W2170741749 creator A5058631034 @default.
- W2170741749 creator A5059255330 @default.
- W2170741749 creator A5065341052 @default.
- W2170741749 creator A5069026924 @default.
- W2170741749 creator A5071286571 @default.
- W2170741749 creator A5071405425 @default.
- W2170741749 creator A5088002732 @default.
- W2170741749 date "2014-11-01" @default.
- W2170741749 modified "2023-09-27" @default.
- W2170741749 title "The Effect of Preoperative Renal Insufficiency on Postoperative Outcomes after Major Hepatectomy: A Multi-Institutional Analysis of 1,170 Patients" @default.
- W2170741749 cites W1965764986 @default.
- W2170741749 cites W1977526588 @default.
- W2170741749 cites W1980141197 @default.
- W2170741749 cites W1981570260 @default.
- W2170741749 cites W1988803469 @default.
- W2170741749 cites W1989812456 @default.
- W2170741749 cites W1991806234 @default.
- W2170741749 cites W2032249211 @default.
- W2170741749 cites W2032822267 @default.
- W2170741749 cites W2034912770 @default.
- W2170741749 cites W2043621964 @default.
- W2170741749 cites W2048373275 @default.
- W2170741749 cites W2054344068 @default.
- W2170741749 cites W2056589151 @default.
- W2170741749 cites W2071129725 @default.
- W2170741749 cites W2073742622 @default.
- W2170741749 cites W2080763375 @default.
- W2170741749 cites W2094413253 @default.
- W2170741749 cites W2096998881 @default.
- W2170741749 cites W2112598337 @default.
- W2170741749 cites W2114951263 @default.
- W2170741749 cites W2115070483 @default.
- W2170741749 cites W2118574202 @default.
- W2170741749 cites W2121635635 @default.
- W2170741749 cites W2125829260 @default.
- W2170741749 cites W2137758715 @default.
- W2170741749 cites W2145947438 @default.
- W2170741749 cites W2146787474 @default.
- W2170741749 cites W2165462019 @default.
- W2170741749 cites W2166170256 @default.
- W2170741749 cites W2169975130 @default.
- W2170741749 cites W2333847126 @default.
- W2170741749 cites W2487377689 @default.
- W2170741749 cites W2473057109 @default.
- W2170741749 doi "https://doi.org/10.1016/j.jamcollsurg.2014.05.015" @default.
- W2170741749 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25260685" @default.
- W2170741749 hasPublicationYear "2014" @default.
- W2170741749 type Work @default.
- W2170741749 sameAs 2170741749 @default.
- W2170741749 citedByCount "18" @default.
- W2170741749 countsByYear W21707417492015 @default.
- W2170741749 countsByYear W21707417492016 @default.
- W2170741749 countsByYear W21707417492017 @default.
- W2170741749 countsByYear W21707417492018 @default.
- W2170741749 countsByYear W21707417492019 @default.
- W2170741749 countsByYear W21707417492020 @default.
- W2170741749 countsByYear W21707417492021 @default.
- W2170741749 crossrefType "journal-article" @default.
- W2170741749 hasAuthorship W2170741749A5002780450 @default.
- W2170741749 hasAuthorship W2170741749A5014218695 @default.
- W2170741749 hasAuthorship W2170741749A5025524746 @default.
- W2170741749 hasAuthorship W2170741749A5026053250 @default.
- W2170741749 hasAuthorship W2170741749A5027872333 @default.
- W2170741749 hasAuthorship W2170741749A5029089899 @default.
- W2170741749 hasAuthorship W2170741749A5036799246 @default.
- W2170741749 hasAuthorship W2170741749A5047326383 @default.
- W2170741749 hasAuthorship W2170741749A5058631034 @default.
- W2170741749 hasAuthorship W2170741749A5059255330 @default.
- W2170741749 hasAuthorship W2170741749A5065341052 @default.
- W2170741749 hasAuthorship W2170741749A5069026924 @default.
- W2170741749 hasAuthorship W2170741749A5071286571 @default.
- W2170741749 hasAuthorship W2170741749A5071405425 @default.
- W2170741749 hasAuthorship W2170741749A5088002732 @default.
- W2170741749 hasConcept C126322002 @default.
- W2170741749 hasConcept C126894567 @default.
- W2170741749 hasConcept C141071460 @default.
- W2170741749 hasConcept C159110652 @default.
- W2170741749 hasConcept C159641895 @default.
- W2170741749 hasConcept C207103383 @default.
- W2170741749 hasConcept C2776909242 @default.
- W2170741749 hasConcept C2778063415 @default.
- W2170741749 hasConcept C2780306776 @default.
- W2170741749 hasConcept C44249647 @default.
- W2170741749 hasConcept C71924100 @default.
- W2170741749 hasConcept C90924648 @default.
- W2170741749 hasConceptScore W2170741749C126322002 @default.
- W2170741749 hasConceptScore W2170741749C126894567 @default.
- W2170741749 hasConceptScore W2170741749C141071460 @default.