Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170765507> ?p ?o ?g. }
- W2170765507 endingPage "1524" @default.
- W2170765507 startingPage "1515" @default.
- W2170765507 abstract "This retrospective study concerns non-bacterial infections in Asian patients receiving alemtuzumab. The clinical data of 182 patients treated with alemtuzumab alone or alemtuzumab-containing chemotherapy between the years 2003 and 2009 was collected from six Asian countries. Alemtuzumab was used in the setting of frontline (n =48) or salvage (n =90) treatment, and as a part of the conditioning regimen for allogeneic stem cell transplant (n =44). Reactivation of cytomegalovirus (66/182) and varicella zoster virus (25/182), and fungal infection (31/182) including invasive pulmonary aspergillosis, were the most common infectious complications in this retrospective analysis. Thus, we recommend routine prophylaxis with valganciclovir and itraconazole, especially when alemtuzumab is used in the conditioning regimen for allogeneic stem cell transplant. Pneumocystis jirovecii pneumonia (PJP) was found in four patients (3%, 4/122) receiving alemtuzumab as conditioning for stem cell transplant or salvage treatment. Three cases of hepatitis B virus reactivation were found in antigen-negative patients, and 16 cases of tuberculosis were observed. Infection is the major complication of alemtuzumab therapy, and these infectious complications are potentially severe and life-threatening. Based on our retrospective analysis, we have constructed a guideline for antimicrobial prophylaxis in Asian patients receiving alemtuzumab therapy." @default.
- W2170765507 created "2016-06-24" @default.
- W2170765507 creator A5004166441 @default.
- W2170765507 creator A5009117622 @default.
- W2170765507 creator A5017743220 @default.
- W2170765507 creator A5017953971 @default.
- W2170765507 creator A5018753809 @default.
- W2170765507 creator A5023506119 @default.
- W2170765507 creator A5036888293 @default.
- W2170765507 creator A5038667383 @default.
- W2170765507 creator A5049891346 @default.
- W2170765507 creator A5062206395 @default.
- W2170765507 creator A5066039159 @default.
- W2170765507 creator A5071885891 @default.
- W2170765507 creator A5074815016 @default.
- W2170765507 creator A5084232585 @default.
- W2170765507 creator A5088824120 @default.
- W2170765507 date "2012-03-01" @default.
- W2170765507 modified "2023-09-24" @default.
- W2170765507 title "Non-bacterial infections in Asian patients treated with alemtuzumab: a retrospective study of the Asian Lymphoma Study Group" @default.
- W2170765507 cites W1976494283 @default.
- W2170765507 cites W1983898630 @default.
- W2170765507 cites W1993086920 @default.
- W2170765507 cites W2003446560 @default.
- W2170765507 cites W2012630504 @default.
- W2170765507 cites W2013558736 @default.
- W2170765507 cites W2013802895 @default.
- W2170765507 cites W2015421929 @default.
- W2170765507 cites W2017979975 @default.
- W2170765507 cites W2027947781 @default.
- W2170765507 cites W2029854218 @default.
- W2170765507 cites W2036156157 @default.
- W2170765507 cites W2043090634 @default.
- W2170765507 cites W2043265202 @default.
- W2170765507 cites W2047279243 @default.
- W2170765507 cites W2047903442 @default.
- W2170765507 cites W2057897174 @default.
- W2170765507 cites W2060499380 @default.
- W2170765507 cites W2061021809 @default.
- W2170765507 cites W2069931850 @default.
- W2170765507 cites W2078447318 @default.
- W2170765507 cites W2078903043 @default.
- W2170765507 cites W2084366804 @default.
- W2170765507 cites W2086716868 @default.
- W2170765507 cites W2087926230 @default.
- W2170765507 cites W2088839692 @default.
- W2170765507 cites W2091485274 @default.
- W2170765507 cites W2092541726 @default.
- W2170765507 cites W2099145932 @default.
- W2170765507 cites W2114733074 @default.
- W2170765507 cites W2130877465 @default.
- W2170765507 cites W2134884957 @default.
- W2170765507 cites W2138955583 @default.
- W2170765507 cites W2140181964 @default.
- W2170765507 cites W2143749371 @default.
- W2170765507 cites W2153859516 @default.
- W2170765507 cites W4248306224 @default.
- W2170765507 doi "https://doi.org/10.3109/10428194.2012.659735" @default.
- W2170765507 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22273250" @default.
- W2170765507 hasPublicationYear "2012" @default.
- W2170765507 type Work @default.
- W2170765507 sameAs 2170765507 @default.
- W2170765507 citedByCount "29" @default.
- W2170765507 countsByYear W21707655072012 @default.
- W2170765507 countsByYear W21707655072013 @default.
- W2170765507 countsByYear W21707655072014 @default.
- W2170765507 countsByYear W21707655072015 @default.
- W2170765507 countsByYear W21707655072016 @default.
- W2170765507 countsByYear W21707655072017 @default.
- W2170765507 countsByYear W21707655072018 @default.
- W2170765507 countsByYear W21707655072019 @default.
- W2170765507 countsByYear W21707655072020 @default.
- W2170765507 countsByYear W21707655072021 @default.
- W2170765507 countsByYear W21707655072022 @default.
- W2170765507 countsByYear W21707655072023 @default.
- W2170765507 crossrefType "journal-article" @default.
- W2170765507 hasAuthorship W2170765507A5004166441 @default.
- W2170765507 hasAuthorship W2170765507A5009117622 @default.
- W2170765507 hasAuthorship W2170765507A5017743220 @default.
- W2170765507 hasAuthorship W2170765507A5017953971 @default.
- W2170765507 hasAuthorship W2170765507A5018753809 @default.
- W2170765507 hasAuthorship W2170765507A5023506119 @default.
- W2170765507 hasAuthorship W2170765507A5036888293 @default.
- W2170765507 hasAuthorship W2170765507A5038667383 @default.
- W2170765507 hasAuthorship W2170765507A5049891346 @default.
- W2170765507 hasAuthorship W2170765507A5062206395 @default.
- W2170765507 hasAuthorship W2170765507A5066039159 @default.
- W2170765507 hasAuthorship W2170765507A5071885891 @default.
- W2170765507 hasAuthorship W2170765507A5074815016 @default.
- W2170765507 hasAuthorship W2170765507A5084232585 @default.
- W2170765507 hasAuthorship W2170765507A5088824120 @default.
- W2170765507 hasConcept C126322002 @default.
- W2170765507 hasConcept C141071460 @default.
- W2170765507 hasConcept C167135981 @default.
- W2170765507 hasConcept C203014093 @default.
- W2170765507 hasConcept C2776391196 @default.
- W2170765507 hasConcept C2779015954 @default.
- W2170765507 hasConcept C2781413609 @default.