FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170789747> ?p ?o ?g. }

• W2170789747 endingPage "2412" @default.
• W2170789747 startingPage "2401" @default.
• W2170789747 abstract "Gram-positive bacteria with a high G+C content are currently recognized as a distinct phylum, Actinobacteria, on the basis of their branching in 16S rRNA trees. Except for an insert in the 23S rRNA, there are no unique biochemical or molecular characteristics known at present that can distinguish this group from all other bacteria. In this work, three conserved indels (i.e. inserts or deletions) are described in three widely distributed proteins that are distinctive characteristics of the Actinobacteria and are not found in any other groups of bacteria. The identified signatures are a 2 aa deletion in cytochrome-c oxidase subunit 1 (Cox1), a 4 aa insert in CTP synthetase and a 5 aa insert in glutamyl-tRNA synthetase (GluRS). Additionally, the actinobacterial specificity of the large insert in the 23S rRNA was also tested. Using primers designed for conserved regions flanking these signatures, fragments of most of these genes were amplified from 23 actinobacterial species, covering many different families and orders, for which no sequence information was previously available. All the 61 sequenced fragments, except two in GluRS, were found to contain the indicated signatures. The presence of these signatures in various species from 20 families within this phylum provides evidence that they are likely distinctive characteristics of the entire phylum, which were introduced in a common ancestor of this group. The absence of all four of these signatures in Symbiobacterium thermophilum suggests that this species, which is distantly related to other actinobacteria in 16S rRNA and CTP synthetase trees, may not be a part of the phylum Actinobacteria. The identified signatures provide novel molecular means for defining and circumscribing the phylum Actinobacteria. Functional studies on them should prove helpful in understanding novel biochemical and physiological characteristics of this group of bacteria." @default.
• W2170789747 created "2016-06-24" @default.
• W2170789747 creator A5060901569 @default.
• W2170789747 creator A5085988586 @default.
• W2170789747 date "2005-11-01" @default.
• W2170789747 modified "2023-10-09" @default.
• W2170789747 title "Conserved indels in protein sequences that are characteristic of the phylum Actinobacteria" @default.
• W2170789747 cites W110771216 @default.
• W2170789747 cites W1539580523 @default.
• W2170789747 cites W1911635991 @default.
• W2170789747 cites W1944107535 @default.
• W2170789747 cites W1971707621 @default.
• W2170789747 cites W1980789643 @default.
• W2170789747 cites W1995014770 @default.
• W2170789747 cites W2003646873 @default.
• W2170789747 cites W2007128729 @default.
• W2170789747 cites W2011261850 @default.
• W2170789747 cites W2012591142 @default.
• W2170789747 cites W2012960603 @default.
• W2170789747 cites W2018756788 @default.
• W2170789747 cites W2020679313 @default.
• W2170789747 cites W2021861325 @default.
• W2170789747 cites W2038955895 @default.
• W2170789747 cites W2052791500 @default.
• W2170789747 cites W2065461553 @default.
• W2170789747 cites W2067314615 @default.
• W2170789747 cites W2078631102 @default.
• W2170789747 cites W2081999492 @default.
• W2170789747 cites W2101719988 @default.
• W2170789747 cites W2104399271 @default.
• W2170789747 cites W2109864391 @default.
• W2170789747 cites W2116574739 @default.
• W2170789747 cites W2130541508 @default.
• W2170789747 cites W2131596454 @default.
• W2170789747 cites W2132195303 @default.
• W2170789747 cites W2135231521 @default.
• W2170789747 cites W2137677665 @default.
• W2170789747 cites W2147565107 @default.
• W2170789747 cites W2148884395 @default.
• W2170789747 cites W2151863305 @default.
• W2170789747 cites W2156330667 @default.
• W2170789747 cites W2156444956 @default.
• W2170789747 cites W2157180542 @default.
• W2170789747 cites W2159678036 @default.
• W2170789747 cites W2160011199 @default.
• W2170789747 cites W2160409135 @default.
• W2170789747 cites W2161681336 @default.
• W2170789747 cites W2161876275 @default.
• W2170789747 cites W2162109874 @default.
• W2170789747 cites W2162923726 @default.
• W2170789747 cites W2172245835 @default.
• W2170789747 cites W4241328656 @default.
• W2170789747 cites W4246548745 @default.
• W2170789747 cites W4247928320 @default.
• W2170789747 cites W4249747683 @default.
• W2170789747 cites W4256386106 @default.
• W2170789747 doi "https://doi.org/10.1099/ijs.0.63785-0" @default.
• W2170789747 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16280504" @default.
• W2170789747 hasPublicationYear "2005" @default.
• W2170789747 type Work @default.
• W2170789747 sameAs 2170789747 @default.
• W2170789747 citedByCount "106" @default.
• W2170789747 countsByYear W21707897472012 @default.
• W2170789747 countsByYear W21707897472013 @default.
• W2170789747 countsByYear W21707897472014 @default.
• W2170789747 countsByYear W21707897472015 @default.
• W2170789747 countsByYear W21707897472016 @default.
• W2170789747 countsByYear W21707897472017 @default.
• W2170789747 countsByYear W21707897472018 @default.
• W2170789747 countsByYear W21707897472019 @default.
• W2170789747 countsByYear W21707897472020 @default.
• W2170789747 countsByYear W21707897472021 @default.
• W2170789747 countsByYear W21707897472022 @default.
• W2170789747 countsByYear W21707897472023 @default.
• W2170789747 crossrefType "journal-article" @default.
• W2170789747 hasAuthorship W2170789747A5060901569 @default.
• W2170789747 hasAuthorship W2170789747A5085988586 @default.
• W2170789747 hasBestOaLocation W21707897471 @default.
• W2170789747 hasConcept C104317684 @default.
• W2170789747 hasConcept C119054055 @default.
• W2170789747 hasConcept C135763542 @default.
• W2170789747 hasConcept C153209595 @default.
• W2170789747 hasConcept C2778169975 @default.
• W2170789747 hasConcept C40749294 @default.
• W2170789747 hasConcept C42062724 @default.
• W2170789747 hasConcept C523546767 @default.
• W2170789747 hasConcept C54355233 @default.
• W2170789747 hasConcept C67705224 @default.
• W2170789747 hasConcept C67905577 @default.
• W2170789747 hasConcept C86803240 @default.
• W2170789747 hasConcept C88478588 @default.
• W2170789747 hasConcept C91066513 @default.
• W2170789747 hasConceptScore W2170789747C104317684 @default.
• W2170789747 hasConceptScore W2170789747C119054055 @default.
• W2170789747 hasConceptScore W2170789747C135763542 @default.
• W2170789747 hasConceptScore W2170789747C153209595 @default.
• W2170789747 hasConceptScore W2170789747C2778169975 @default.
• W2170789747 hasConceptScore W2170789747C40749294 @default.

• next