FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170804940> ?p ?o ?g. }

• W2170804940 endingPage "11" @default.
• W2170804940 startingPage "1" @default.
• W2170804940 abstract "Ferric ion binding proteins (Fbps) transport<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mrow><mml:msup><mml:mrow><mml:mtext>Fe</mml:mtext></mml:mrow><mml:mrow><mml:mtext>III</mml:mtext></mml:mrow></mml:msup></mml:mrow></mml:math>across the periplasm and are vital for the virulence of many Gram negative bacteria. Iron(III) is tightly bound in a hinged binding cleft with octahedral coordination geometry involving binding to protein side chains (including tyrosinate residues) together with a synergistic anion such as phosphate. Niobium compounds are of interest for their potential biological activity, which has been little explored. We have studied the binding of cyclopentadienyl and nitrilotriacetato<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mrow><mml:msup><mml:mrow><mml:mtext>Nb</mml:mtext></mml:mrow><mml:mtext>V</mml:mtext></mml:msup></mml:mrow></mml:math>complexes to the Fbp from Neisseria gonorrhoeae by UV-vis spectroscopy, chromatography, ICP-OES, mass spectrometry, and Nb K-edge X-ray absorption spectroscopy. These data suggest that<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mrow><mml:msup><mml:mrow><mml:mtext>Nb</mml:mtext></mml:mrow><mml:mtext>V</mml:mtext></mml:msup></mml:mrow></mml:math>binds strongly to Fbp and that a dinuclear<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mrow><mml:msup><mml:mrow><mml:mtext>Nb</mml:mtext></mml:mrow><mml:mtext>V</mml:mtext></mml:msup></mml:mrow></mml:math>centre can be readily accommodated in the interdomain binding cleft. The possibility of designing niobium-based antibiotics which block iron uptake by pathogenic bacteria is discussed." @default.
• W2170804940 created "2016-06-24" @default.
• W2170804940 creator A5049966017 @default.
• W2170804940 creator A5071465820 @default.
• W2170804940 creator A5071855899 @default.
• W2170804940 creator A5074147836 @default.
• W2170804940 date "2010-01-01" @default.
• W2170804940 modified "2023-09-25" @default.
• W2170804940 title "Niobium Uptake and Release by Bacterial Ferric Ion Binding Protein" @default.
• W2170804940 cites W1556983269 @default.
• W2170804940 cites W1967716470 @default.
• W2170804940 cites W1970654416 @default.
• W2170804940 cites W1974075450 @default.
• W2170804940 cites W1980185626 @default.
• W2170804940 cites W1984171890 @default.
• W2170804940 cites W1991588605 @default.
• W2170804940 cites W1995366948 @default.
• W2170804940 cites W2001828454 @default.
• W2170804940 cites W2006636818 @default.
• W2170804940 cites W2015694743 @default.
• W2170804940 cites W2016050070 @default.
• W2170804940 cites W2021497905 @default.
• W2170804940 cites W2028928977 @default.
• W2170804940 cites W2030109318 @default.
• W2170804940 cites W2033210527 @default.
• W2170804940 cites W2033684040 @default.
• W2170804940 cites W2039149939 @default.
• W2170804940 cites W2045562184 @default.
• W2170804940 cites W2067062848 @default.
• W2170804940 cites W2070254932 @default.
• W2170804940 cites W2081539877 @default.
• W2170804940 cites W2083526260 @default.
• W2170804940 cites W2084540599 @default.
• W2170804940 cites W2092994445 @default.
• W2170804940 cites W2120680516 @default.
• W2170804940 cites W2133710714 @default.
• W2170804940 cites W2161424310 @default.
• W2170804940 cites W2165972373 @default.
• W2170804940 cites W2170310819 @default.
• W2170804940 cites W2437946319 @default.
• W2170804940 cites W293747239 @default.
• W2170804940 cites W4246581327 @default.
• W2170804940 cites W4321429130 @default.
• W2170804940 cites W71105841 @default.
• W2170804940 doi "https://doi.org/10.1155/2010/307578" @default.
• W2170804940 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2860717" @default.
• W2170804940 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20445753" @default.
• W2170804940 hasPublicationYear "2010" @default.
• W2170804940 type Work @default.
• W2170804940 sameAs 2170804940 @default.
• W2170804940 citedByCount "7" @default.
• W2170804940 countsByYear W21708049402012 @default.
• W2170804940 countsByYear W21708049402013 @default.
• W2170804940 countsByYear W21708049402018 @default.
• W2170804940 countsByYear W21708049402020 @default.
• W2170804940 crossrefType "journal-article" @default.
• W2170804940 hasAuthorship W2170804940A5049966017 @default.
• W2170804940 hasAuthorship W2170804940A5071465820 @default.
• W2170804940 hasAuthorship W2170804940A5071855899 @default.
• W2170804940 hasAuthorship W2170804940A5074147836 @default.
• W2170804940 hasBestOaLocation W21708049401 @default.
• W2170804940 hasConcept C11413529 @default.
• W2170804940 hasConcept C185592680 @default.
• W2170804940 hasConcept C41008148 @default.
• W2170804940 hasConceptScore W2170804940C11413529 @default.
• W2170804940 hasConceptScore W2170804940C185592680 @default.
• W2170804940 hasConceptScore W2170804940C41008148 @default.
• W2170804940 hasFunder F4320307874 @default.
• W2170804940 hasLocation W21708049401 @default.
• W2170804940 hasLocation W21708049402 @default.
• W2170804940 hasLocation W21708049403 @default.
• W2170804940 hasLocation W21708049404 @default.
• W2170804940 hasLocation W21708049405 @default.
• W2170804940 hasLocation W21708049406 @default.
• W2170804940 hasOpenAccess W2170804940 @default.
• W2170804940 hasPrimaryLocation W21708049401 @default.
• W2170804940 hasRelatedWork W1531601525 @default.
• W2170804940 hasRelatedWork W1990781990 @default.
• W2170804940 hasRelatedWork W2319480705 @default.
• W2170804940 hasRelatedWork W2384464875 @default.
• W2170804940 hasRelatedWork W2606230654 @default.
• W2170804940 hasRelatedWork W2607424097 @default.
• W2170804940 hasRelatedWork W2748952813 @default.
• W2170804940 hasRelatedWork W2899084033 @default.
• W2170804940 hasRelatedWork W2948807893 @default.
• W2170804940 hasRelatedWork W2778153218 @default.
• W2170804940 hasVolume "2010" @default.
• W2170804940 isParatext "false" @default.
• W2170804940 isRetracted "false" @default.
• W2170804940 magId "2170804940" @default.
• W2170804940 workType "article" @default.