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• W2170848162 endingPage "83" @default.
• W2170848162 startingPage "72" @default.
• W2170848162 abstract "Summary: Transmembrane adapter proteins (TRAPs) are critical components of signaling pathways in lymphocytes, linking antigen receptor engagement to downstream cellular processes. While these proteins lack intrinsic enzymatic activity, their phosphorylation following receptor ligation allows them to function as scaffolds for the assembly of multi‐molecular signaling complexes. Many TRAPs have recently been discovered, and numerous studies demonstrate their roles in the positive and negative regulation of lymphocyte maturation, activation, and differentiation. One such example is the linker for activation of T cells (LAT) family of adapter proteins. While LAT has been shown to play an indispensable role in T‐cell and mast cell function, the other family members, linker for activation of B cells (LAB) and linker for activation of X cells (LAX), are necessary to fine‐tune immune responses. In addition to its well‐established role in the positive regulation of lymphocyte activation, LAT exerts an inhibitory effect on T‐cell receptor‐mediated signaling. Furthermore, LAT, along with LAB and LAX, plays a crucial role in establishing and maintaining tolerance. Here, we review recent data concerning the regulation of lymphocyte development and activation by the LAT family of proteins." @default.
• W2170848162 created "2016-06-24" @default.
• W2170848162 creator A5039044513 @default.
• W2170848162 creator A5082194512 @default.
• W2170848162 date "2009-10-23" @default.
• W2170848162 modified "2023-10-14" @default.
• W2170848162 title "Regulation of lymphocyte development and activation by the LAT family of adapter proteins" @default.
• W2170848162 cites W1481671615 @default.
• W2170848162 cites W1503017065 @default.
• W2170848162 cites W1509906249 @default.
• W2170848162 cites W1519310145 @default.
• W2170848162 cites W1521040393 @default.
• W2170848162 cites W1527257674 @default.
• W2170848162 cites W1534253341 @default.
• W2170848162 cites W1557825564 @default.
• W2170848162 cites W1575040416 @default.
• W2170848162 cites W1603362495 @default.
• W2170848162 cites W1634654311 @default.
• W2170848162 cites W1636850312 @default.
• W2170848162 cites W1693076983 @default.
• W2170848162 cites W1699431440 @default.
• W2170848162 cites W1804861156 @default.
• W2170848162 cites W1824062321 @default.
• W2170848162 cites W188697156 @default.
• W2170848162 cites W1925024750 @default.
• W2170848162 cites W1935162250 @default.
• W2170848162 cites W1965053438 @default.
• W2170848162 cites W1965208564 @default.
• W2170848162 cites W1965712069 @default.
• W2170848162 cites W1977156769 @default.
• W2170848162 cites W1980907115 @default.
• W2170848162 cites W1981087559 @default.
• W2170848162 cites W1981205839 @default.
• W2170848162 cites W1988164325 @default.
• W2170848162 cites W1992438206 @default.
• W2170848162 cites W1996822762 @default.
• W2170848162 cites W1998679748 @default.
• W2170848162 cites W1999447682 @default.
• W2170848162 cites W2007124301 @default.
• W2170848162 cites W2011235374 @default.
• W2170848162 cites W2014177218 @default.
• W2170848162 cites W2025823475 @default.
• W2170848162 cites W2030630541 @default.
• W2170848162 cites W2031514258 @default.
• W2170848162 cites W2035018883 @default.
• W2170848162 cites W2042209841 @default.
• W2170848162 cites W2043040868 @default.
• W2170848162 cites W2043208930 @default.
• W2170848162 cites W2047132622 @default.
• W2170848162 cites W2047265140 @default.
• W2170848162 cites W2050433730 @default.
• W2170848162 cites W2054011315 @default.
• W2170848162 cites W2054458458 @default.
• W2170848162 cites W2055864348 @default.
• W2170848162 cites W2055965228 @default.
• W2170848162 cites W2061351491 @default.
• W2170848162 cites W2063060777 @default.
• W2170848162 cites W2065886456 @default.
• W2170848162 cites W2067752213 @default.
• W2170848162 cites W2068204192 @default.
• W2170848162 cites W2073526321 @default.
• W2170848162 cites W2077518158 @default.
• W2170848162 cites W2081613818 @default.
• W2170848162 cites W2083380661 @default.
• W2170848162 cites W2092867329 @default.
• W2170848162 cites W2093076684 @default.
• W2170848162 cites W2096613461 @default.
• W2170848162 cites W2097811455 @default.
• W2170848162 cites W2099738473 @default.
• W2170848162 cites W2100009822 @default.
• W2170848162 cites W2100646106 @default.
• W2170848162 cites W2102174567 @default.
• W2170848162 cites W2104431870 @default.
• W2170848162 cites W2104795242 @default.
• W2170848162 cites W2106198450 @default.
• W2170848162 cites W2106251488 @default.
• W2170848162 cites W2109479443 @default.
• W2170848162 cites W2113536356 @default.
• W2170848162 cites W2117011078 @default.
• W2170848162 cites W2118738797 @default.
• W2170848162 cites W2129108588 @default.
• W2170848162 cites W2131281845 @default.
• W2170848162 cites W2131423590 @default.
• W2170848162 cites W2133084626 @default.
• W2170848162 cites W2147055245 @default.
• W2170848162 cites W2148269724 @default.
• W2170848162 cites W2149650496 @default.
• W2170848162 cites W2152027730 @default.
• W2170848162 cites W2152093499 @default.
• W2170848162 cites W2157689835 @default.
• W2170848162 cites W2160675888 @default.
• W2170848162 cites W2163617437 @default.
• W2170848162 cites W2163955606 @default.
• W2170848162 cites W2165718358 @default.
• W2170848162 cites W2167548535 @default.
• W2170848162 cites W2168457547 @default.
• W2170848162 cites W2169884545 @default.
• W2170848162 cites W2171480972 @default.

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