FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170854597> ?p ?o ?g. }

• W2170854597 endingPage "209" @default.
• W2170854597 startingPage "205" @default.
• W2170854597 abstract "The gene expression profile in rat brain was examined using microarrays in rats fed lithium chloride for 7 days (subacute) or 42 days (chronic). Brain lithium concentrations were 0.39 mM and 0.79 mM (therapeutically relevant), at 7 and 42 days, respectively. Of the 4132 genes represented in the microarrays, 25 genes were downregulated by at least twofold and none was upregulated after 7 days of treatment. Expression of 50 genes was downregulated by at least two-fold at 42 days, without any being upregulated. Lithium treatment for 7 days did not affect at a measurable extent expression of 37 of the 50 genes that were downregulated at 42 days. Genes whose expression was changed at 42 days coded for a number of receptors, protein kinases, transcription and translation factors, markers of energy metabolism, and signal transduction. Thus, chronic lithium at a therapeutically relevant concentration reduced expression of a large number of genes involved in multiple signaling and other pathways, without increasing expression at a comparable extent." @default.
• W2170854597 created "2016-06-24" @default.
• W2170854597 creator A5011234589 @default.
• W2170854597 creator A5019747475 @default.
• W2170854597 creator A5042479690 @default.
• W2170854597 creator A5055057772 @default.
• W2170854597 creator A5069116902 @default.
• W2170854597 creator A5079123323 @default.
• W2170854597 creator A5090383953 @default.
• W2170854597 date "2002-01-01" @default.
• W2170854597 modified "2023-10-03" @default.
• W2170854597 title "Analysis of gene expression with cDNA microarrays in rat brain after 7 and 42 days of oral lithium administration" @default.
• W2170854597 cites W1927894522 @default.
• W2170854597 cites W195212044 @default.
• W2170854597 cites W1968436352 @default.
• W2170854597 cites W1974505399 @default.
• W2170854597 cites W1984935769 @default.
• W2170854597 cites W1996185163 @default.
• W2170854597 cites W2003421939 @default.
• W2170854597 cites W2008137448 @default.
• W2170854597 cites W2022257217 @default.
• W2170854597 cites W2027126110 @default.
• W2170854597 cites W2027704731 @default.
• W2170854597 cites W2032993006 @default.
• W2170854597 cites W2034699832 @default.
• W2170854597 cites W2036111134 @default.
• W2170854597 cites W2038954486 @default.
• W2170854597 cites W2044239520 @default.
• W2170854597 cites W2057779233 @default.
• W2170854597 cites W2062266687 @default.
• W2170854597 cites W2069659006 @default.
• W2170854597 cites W2072153774 @default.
• W2170854597 cites W2073264699 @default.
• W2170854597 cites W2083942007 @default.
• W2170854597 cites W2088878613 @default.
• W2170854597 cites W2089769517 @default.
• W2170854597 cites W2092026193 @default.
• W2170854597 cites W2094613397 @default.
• W2170854597 cites W2106918877 @default.
• W2170854597 cites W2127230663 @default.
• W2170854597 cites W2151140831 @default.
• W2170854597 cites W2152392558 @default.
• W2170854597 cites W2166260758 @default.
• W2170854597 cites W2169898794 @default.
• W2170854597 cites W4250845827 @default.
• W2170854597 doi "https://doi.org/10.1016/s0361-9230(01)00744-4" @default.
• W2170854597 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11849827" @default.
• W2170854597 hasPublicationYear "2002" @default.
• W2170854597 type Work @default.
• W2170854597 sameAs 2170854597 @default.
• W2170854597 citedByCount "75" @default.
• W2170854597 countsByYear W21708545972012 @default.
• W2170854597 countsByYear W21708545972013 @default.
• W2170854597 countsByYear W21708545972014 @default.
• W2170854597 countsByYear W21708545972015 @default.
• W2170854597 countsByYear W21708545972016 @default.
• W2170854597 countsByYear W21708545972017 @default.
• W2170854597 countsByYear W21708545972018 @default.
• W2170854597 countsByYear W21708545972019 @default.
• W2170854597 countsByYear W21708545972021 @default.
• W2170854597 countsByYear W21708545972023 @default.
• W2170854597 crossrefType "journal-article" @default.
• W2170854597 hasAuthorship W2170854597A5011234589 @default.
• W2170854597 hasAuthorship W2170854597A5019747475 @default.
• W2170854597 hasAuthorship W2170854597A5042479690 @default.
• W2170854597 hasAuthorship W2170854597A5055057772 @default.
• W2170854597 hasAuthorship W2170854597A5069116902 @default.
• W2170854597 hasAuthorship W2170854597A5079123323 @default.
• W2170854597 hasAuthorship W2170854597A5090383953 @default.
• W2170854597 hasConcept C104317684 @default.
• W2170854597 hasConcept C127561419 @default.
• W2170854597 hasConcept C150194340 @default.
• W2170854597 hasConcept C153911025 @default.
• W2170854597 hasConcept C165864922 @default.
• W2170854597 hasConcept C170493617 @default.
• W2170854597 hasConcept C178790620 @default.
• W2170854597 hasConcept C18431079 @default.
• W2170854597 hasConcept C185592680 @default.
• W2170854597 hasConcept C186836561 @default.
• W2170854597 hasConcept C187882448 @default.
• W2170854597 hasConcept C2779018089 @default.
• W2170854597 hasConcept C2780990938 @default.
• W2170854597 hasConcept C54355233 @default.
• W2170854597 hasConcept C62478195 @default.
• W2170854597 hasConcept C77360908 @default.
• W2170854597 hasConcept C8415881 @default.
• W2170854597 hasConcept C86803240 @default.
• W2170854597 hasConcept C95371953 @default.
• W2170854597 hasConcept C95444343 @default.
• W2170854597 hasConceptScore W2170854597C104317684 @default.
• W2170854597 hasConceptScore W2170854597C127561419 @default.
• W2170854597 hasConceptScore W2170854597C150194340 @default.
• W2170854597 hasConceptScore W2170854597C153911025 @default.
• W2170854597 hasConceptScore W2170854597C165864922 @default.
• W2170854597 hasConceptScore W2170854597C170493617 @default.
• W2170854597 hasConceptScore W2170854597C178790620 @default.
• W2170854597 hasConceptScore W2170854597C18431079 @default.
• W2170854597 hasConceptScore W2170854597C185592680 @default.

• next