FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2170888107> ?p ?o ?g. }

• W2170888107 endingPage "5051" @default.
• W2170888107 startingPage "5050" @default.
• W2170888107 abstract "With great interest, we read the recent article entitled with “Ivabradine significantly improves cardiac function in patients with ischemic heart disease: A meta-analysis of randomized controlled trials” [1]. The authors included 7 randomized controlled trials with a total of 1542 patients for meta-analysis and concluded that Ivabradine significantly improved cardiac function in patients with ischemic heart disease. In our opinion, this is an interesting manuscript analyzing the effects of Ivabradine on left ventricular function in patientswith ischemic heart disease. To enrich the study conducted by Peng et al., we have several comments as follows: Firstly, the authors performed an extensive search from6databases by using the following keywords/Medical Subject Headings: “Ivabradine plus myocardial infarction or angina or ischemic cardiomyopathy or heart failure or coronary artery disease or ischemic heart disease”. The search was restricted to “randomized controlled trial”. The literature search generated 482 publications of randomized controlled trials on Ivabradine for ischemicheartdisease.However, thedetailed searchalgorithmwasnot provided in the meta-analysis. A quick search using the online database “PubMed” with the search algorithm “(Ivabradine) AND randomized controlled trial” only generated 107 publications until July 4, 2013. And actually a considerable portion of the 107 results were not randomized controlled trials. According to the Cochrane Handbook [2], a thorough, objective and reproducible search strategy is critical to minimize the bias. Secondly, according to the authors, the criteria of an eligible study were: 1) randomized controlled trial; 2) patients with ischemic heart disease; 3) Ivabradine was used in one of the intervention group; and 4) outcome evaluation included LVEF as left ventricular function. The definition of ischemic heart disease in US National Library of Medicine was “A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart”. For the seven eligible studies in this meta-analysis, the primary criteria for including patientswere: “stable angina” [3]; “idiopathic dilated cardiomyopathy with chronic heart failure” [4]; “left ventricular dysfunction” [5]; “ischemic chronic heart failure” [6]; “stable coronary artery disease and left-ventricular systolic dysfunction” [7]; “early phases of reperfused anterior myocardial infarction with impaired left ventricular function” [8]; and “chronic heart failure” [9]. Due to the discrepancy between studies on the including criteria, it is highly possible that some patients included in the meta-analysis might not meet the diagnosis standard of ischemic heart disease. Thirdly, the characteristics of seven eligible studies were not summarized accurately in the main text, although the first table in the original article provided lots of information. In the study by Manz et al., [5] only a single intravenous dose of Ivabradine (0.25 mg/kg) was given to the patients and the left ventricular function was evaluated at 0 and 2 hours after injection. Ivabradine was administered" @default.
• W2170888107 created "2016-06-24" @default.
• W2170888107 creator A5006175809 @default.
• W2170888107 creator A5049692788 @default.
• W2170888107 date "2013-10-01" @default.
• W2170888107 modified "2023-10-14" @default.
• W2170888107 title "Effects of Ivabradine on left ventricular function in patients with ischemic heart disease" @default.
• W2170888107 cites W1966200033 @default.
• W2170888107 cites W1981206847 @default.
• W2170888107 cites W1999660133 @default.
• W2170888107 cites W2006112185 @default.
• W2170888107 cites W2019468355 @default.
• W2170888107 cites W2062837386 @default.
• W2170888107 cites W2089440917 @default.
• W2170888107 cites W2115071060 @default.
• W2170888107 cites W2170675714 @default.
• W2170888107 cites W2906992465 @default.
• W2170888107 doi "https://doi.org/10.1016/j.ijcard.2013.07.213" @default.
• W2170888107 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23968718" @default.
• W2170888107 hasPublicationYear "2013" @default.
• W2170888107 type Work @default.
• W2170888107 sameAs 2170888107 @default.
• W2170888107 citedByCount "2" @default.
• W2170888107 countsByYear W21708881072015 @default.
• W2170888107 countsByYear W21708881072016 @default.
• W2170888107 crossrefType "journal-article" @default.
• W2170888107 hasAuthorship W2170888107A5006175809 @default.
• W2170888107 hasAuthorship W2170888107A5049692788 @default.
• W2170888107 hasConcept C126322002 @default.
• W2170888107 hasConcept C164705383 @default.
• W2170888107 hasConcept C2777953023 @default.
• W2170888107 hasConcept C2779167562 @default.
• W2170888107 hasConcept C2993376042 @default.
• W2170888107 hasConcept C71924100 @default.
• W2170888107 hasConcept C84393581 @default.
• W2170888107 hasConceptScore W2170888107C126322002 @default.
• W2170888107 hasConceptScore W2170888107C164705383 @default.
• W2170888107 hasConceptScore W2170888107C2777953023 @default.
• W2170888107 hasConceptScore W2170888107C2779167562 @default.
• W2170888107 hasConceptScore W2170888107C2993376042 @default.
• W2170888107 hasConceptScore W2170888107C71924100 @default.
• W2170888107 hasConceptScore W2170888107C84393581 @default.
• W2170888107 hasIssue "5" @default.
• W2170888107 hasLocation W21708881071 @default.
• W2170888107 hasLocation W21708881072 @default.
• W2170888107 hasOpenAccess W2170888107 @default.
• W2170888107 hasPrimaryLocation W21708881071 @default.
• W2170888107 hasRelatedWork W2047586453 @default.
• W2170888107 hasRelatedWork W2051343012 @default.
• W2170888107 hasRelatedWork W2062837386 @default.
• W2170888107 hasRelatedWork W2079604044 @default.
• W2170888107 hasRelatedWork W2153024526 @default.
• W2170888107 hasRelatedWork W2223146702 @default.
• W2170888107 hasRelatedWork W2270377498 @default.
• W2170888107 hasRelatedWork W2472855948 @default.
• W2170888107 hasRelatedWork W2518714549 @default.
• W2170888107 hasRelatedWork W3113728533 @default.
• W2170888107 hasVolume "168" @default.
• W2170888107 isParatext "false" @default.
• W2170888107 isRetracted "false" @default.
• W2170888107 magId "2170888107" @default.
• W2170888107 workType "article" @default.