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• W2170889586 abstract "The M protein and streptococcus pyrogenic exotoxin (SPE A) are important virulence factors in group A streptococci (GAS) infections. The emm types of GAS strains isolated from patients with sepsis were determined by sequencing the 5' N-terminus of the emm gene, encoding the M protein, and clonality analysis using pulsed-field gel electrophoresis. The presence of speA and production of SPE A were also examined. There were no predominant GAS clones. The emm genotypes were variable, and the most common genotype was emm13 (17.9%). The production prevalence of SPE A was 21.4%. The low mortality rate (7.1%) of GAS sepsis might be attributable to the low incidence of virulent strains such as emm1 (10.7%) and emm3 (7.1%), as well as to low production rate of SPE A." @default.
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• W2170889586 date "2006-01-01" @default.
• W2170889586 modified "2023-09-25" @default.
• W2170889586 title "Genetic Diversity and Exotoxin A Production of Group A Streptococci Causing Sepsis" @default.
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• W2170889586 doi "https://doi.org/10.3346/jkms.2006.21.2.193" @default.
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