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- W2170990970 abstract "We applaud the recent survey by Riedl et al [1] Riedl M. Gower R.G. Chrvala C.A. Current medical management of hereditary angioedema: results from a large survey of US physicians. Ann Allergy Asthma Immunol. 2011; 106: 316-322 Abstract Full Text Full Text PDF PubMed Scopus (37) Google Scholar demonstrating that many allergists are unfamiliar with the new therapeutic agents recently approved for hereditary angioedema (HAE). Today is probably the most fortuitous time to be an HAE patient. Five new therapies either have been approved or are in development for HAE, an orphan disease for which we have had few treatments to offer our patients. Current medical management of hereditary angioedema: results from a large survey of US physiciansAnnals of Allergy, Asthma & ImmunologyVol. 106Issue 4PreviewHereditary angioedema (HAE) is a potentially life-threatening condition that affects approximately 1 in 50,000 persons. There are no known surveys of US physicians' knowledge and experience regarding the epidemiology, diagnosis, and management of HAE. Full-Text PDF Author's responseAnnals of Allergy, Asthma & ImmunologyVol. 109Issue 2PreviewWe appreciate the Kalfus et al1 commentary as a valuable contribution to the discussion of issues related to the management of patients with hereditary angioedema (HAE). We agree completely with most of the points made by these authors. For example, we agree that the availability of new HAE therapies has led to questions regarding which option to choose; that patient-specific, individualized care decisions are appropriate for each HAE patient; and that the new therapies have the potential to improve the morbidity of HAE that can only be described as “life altering.” We also agree that as an orphan disease, the HAE treatments that have navigated through the FDA approval process in today's world are justifiably very expensive, and that the cost dilemma of the new HAE therapies is difficult to resolve. Full-Text PDF" @default.
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- W2170990970 date "2012-08-01" @default.
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- W2170990970 title "Hereditary angioedema: implications of treating a rare disease" @default.
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- W2170990970 doi "https://doi.org/10.1016/j.anai.2012.06.011" @default.
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