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- W2170999132 abstract "This article aims to provide a theoretical framework to elucidate the neurophysiological underpinnings of deviance detection as reflected by mismatch negativity. A six-step model of the information processing necessary for deviance detection is proposed. In this model, predictive coding of learned regularities is realized by means of long-term potentiation with a crucial role for NMDA receptors. Mismatch negativity occurs at the last stage of the model, reflecting the increase in free energy associated with the switching on of silent synapses and the formation of new neural circuits required for adaptation to the environmental deviance. The model is discussed with regard to the pathological states most studied in relation to mismatch negativity: alcohol intoxication, alcohol withdrawal, and schizophrenia." @default.
- W2170999132 created "2016-06-24" @default.
- W2170999132 creator A5017243814 @default.
- W2170999132 date "2007-12-01" @default.
- W2170999132 modified "2023-10-15" @default.
- W2170999132 title "Can mismatch negativity be linked to synaptic processes? A glutamatergic approach to deviance detection" @default.
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- W2170999132 doi "https://doi.org/10.1016/j.bandc.2007.04.002" @default.
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